Tomer Milo

130 posts

Tomer Milo

Tomer Milo

@MiloTomer

Postdoc @ the Wong lab | MIT & Ragon Institute | Quantitative Systems Immunology

เข้าร่วม Mart 2018
263 กำลังติดตาม107 ผู้ติดตาม
Tomer Milo รีทวีตแล้ว
Weizmann Institute
Weizmann Institute@WeizmannScience·
אנחנו נמצאים בנקודת זמן קריטית לשיקום מכון ויצמן למדע, וזקוקים לתמיכה שלך. בעזרתך נוכל לבנות מחדש מעבדות, לבסס מחדש מחקרים פורצי דרך ולהוביל את המדע לגבהים חדשים. התרומה שלך היום תניע את התגליות של מחר. עכשיו זה הזמן. לתמיכה >>
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Tomer Milo รีทวีตแล้ว
Weizmann Institute
Weizmann Institute@WeizmannScience·
A prosperous future is intertwined with science and innovation. And right now, our science needs rebuilding. Help us restore the heart of discovery. Support the Weizmann Institute of Science. DONATE NOW >>
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Tomer Milo
Tomer Milo@MiloTomer·
@HarikeshWong Thanks Hari for your mentorship. You had a significant contribution to that achievement.
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Tomer Milo รีทวีตแล้ว
Harikesh Wong
Harikesh Wong@HarikeshWong·
Out today in @ScienceMagazine! We show that rising self-antigen levels during infection give self-reactive T cells an opportunity for enhanced TCR signalling. Regulatory T cells of matched specificity counteract this, thereby preventing autoimmunity. buff.ly/3EXaXQa
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Tomer Milo
Tomer Milo@MiloTomer·
We think the ability of endocrine glands to adjust their mass might explain why several promising drugs that target cortisol, the stress hormone, fail in clinical trials for mood disorders. We propose a new target - CRH. Hormonal feedback circuits can be tricky. @UriAlonWeizmann
bioRxiv SysBio@biorxiv_sysbio

Hormone circuit analysis explains why most HPA drugs fail for mood disorders and predicts the few that work biorxiv.org/cgi/content/sh… #biorxiv_sysbio

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Tomer Milo รีทวีตแล้ว
Andreas Tiffeau-Mayer
Andreas Tiffeau-Mayer@andimscience·
Lightning-fast adaptive immune receptor similarity search by symmetric deletion lookup arxiv.org/abs/2403.09010 In work led by @heartnetkung we show how an algorithmic paradigm from spell checking can accelerate TCR clustering by orders of magnitude
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Tomer Milo รีทวีตแล้ว
Omer Karin
Omer Karin@omer_karin·
Our theory paper on plasma cells is out. Protection following vaccination or infection depends to a large extent on the survival of plasma cells, but what determines their lifespan in the body? cell.com/immunity/fullt…
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Tomer Milo รีทวีตแล้ว
Uri Alon
Uri Alon@UriAlonWeizmann·
We are now using the model to identify HPA drug targets to lower cortisol, see upcoming work by @MiloTomer
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Tomer Milo
Tomer Milo@MiloTomer·
Here we suggest that mood fluctuations in bipolar disorder is driven by cortisol slow (months-scale) dynamics. It was a long journey of sharpening our premise and I am glad it is finally out :)
Uri Alon@UriAlonWeizmann

A new mechanism for bipolar disorder. We measured hair cortisol over 12 months, and used large scale data on moods and our math model of the stress HPA axis, to propose how mood swings are generated. #SystemsMedicine #ComputationalPsychiatry sciencedirect.com/science/articl…

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Uri Alon
Uri Alon@UriAlonWeizmann·
E. coli engineered to become stem cells that differentiate! We prevent take-over by mutant stem cells that only self renew - by linking differentiation to an essential function. A new way to engineer stable microbial communities. sciencedirect.com/science/articl…
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Tomer Milo รีทวีตแล้ว
Miri Adler
Miri Adler@MiriAdler·
Started my new position as a senior lecturer (Assistant Professor) at the Alexander Silberman Institute of Life Sciences and the Faculty of Medicine at @HebrewU. We develop computational frameworks to study fundamental principles of tissues in both health and disease contexts.
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Tomer Milo รีทวีตแล้ว
Uri Alon
Uri Alon@UriAlonWeizmann·
Why do we get certain diseases whereas others do not exist? This new book builds a foundation for systems medicine. Starting from basic laws, it derives why hormone, immune and aging circuits are built the way the are, culminating in a periodic table of diseases.
Uri Alon tweet media
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Tomer Milo รีทวีตแล้ว
Shaul Amsterdamski 🤞
Shaul Amsterdamski 🤞@amsterdamski2·
This makes me sick to my stomach. Absolutely horrific
Rep. Elise Stefanik@RepStefanik

🚨🚨🚨Presidents of @Harvard @MIT and @Penn REFUSE to say whether “calling for the genocide of Jews” is bullying and harassment according to their codes of conduct. Even going so far to say it needs to turn to “action” first. As in committing genocide. THIS IS UNACCEPTABLE AND ANTISEMITIC. They must all resign immediately today.

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ค้นพบ

@CellCellPress @ragoninstitute @MITBiology @HarikeshWong @ScienceMagazine @MiyaraShoval @MolSystBiol @NirShiraz