Pharmacotherapy

Contemporary simultaneous heart–kidney transplantation recipients (SHKT) experience similar 1-year outcomes across induction strategies. Basiliximab may be sufficient for standard-risk SHKT recipients. buff.ly/32hQK1w

Combination therapy was well tolerated and significantly reduced urinary albumin-to-creatinine ratio compared with monotherapy buff.ly/oxQBFWK

Drawing a metaphor from drug development, various opportunities to collect empirical evidence through post-marketing surveillance are available and represent rabbit holes that may lead to unexpected benefits of contemporary drug therapy. buff.ly/wUxWCPd

Despite heterogeneity in study design and outcome measures, consistent reductions in binge eating behaviors were observed, reflected by improvements in Binge Eating Scale scores, reductions in binge frequency, and remission rates. buff.ly/8yB1bhe

Overall adherence to direct-acting antiviral agents therapy was high in HCV; however, several clinical and non-clinical factors were associated with non-adherence. buff.ly/vk8KHj6

The future of drug therapy is here. This @PharmacoJournal themed issue on AI applications explores how machine learning & big data are reshaping pharmacotherapy, improving how we optimize care for patients. @ACCP #AIinHealthcare ow.ly/LmWH50YyEgI

Congratulations to ACCP member Laura Cotiguala and co-authors on the recent publication of their article in Pharmacotherapy! Access the abstract and/or article here: ow.ly/NNRZ50Y4gcp #MakingAnImpact #ACCP

Congratulations to ACCP member Lauren R. Cirrincione and co-authors on the recent publication of their article in Pharmacotherapy! Access the abstract and/or article here: ow.ly/lLeo50YicGO #MakingAnImpact #ACCP #OpenAccess @PharmacoJournal

The mortality and economic burden of drug-induced acute kidney injury are substantial, emphasizing the need for prevention and optimal treatment. Listen to how novel biomarkers may be a missing piece of the assessment for early detection & management. buff.ly/hGCSaO8

Antibiotics in pregnancy: what's safe, what's new, and what every clinician needs to know. 💊 The 2025 updated review in @PharmacoJournal has the answers you need to improve care. ow.ly/uA7550YBbSn @ACCP #AntibioticsInPregnancy #PregnancySafety #PregnancyCare

The latest #ClinicalPharmacy and #DrugTherapy research is waiting for you. View the latest research from @JACCPJournal and @PharmacoJournal . Bookmark it. Share it. Come back often. @ACCP #HealthcareInnovation ow.ly/9yE650YBc6T

This study demonstrated the potential CV benefit of GLP-1 RA therapies among a population of female breast cancer survivors with T2D. buff.ly/AMYIMlY

Although there are few studies assessing hormone therapy and cancer risk in transgender individuals, available studies show no increased risk of cervical, ovarian, testicular, and prostate cancer associated with gender-affirming hormone therapy. buff.ly/HY8W4gh

Innovative. Peer-reviewed. Patient-focused. 🔬 Pharmacotherapy is the go-to journal for cutting-edge research on human pharmacology and drug therapy — an official journal of the @ACCP. Explore the latest research from @PharmacoJournal . ow.ly/vjq350YyELS

This study in @PharmacoJournal introduces DILIConsult — an agentic AI pipeline built on GPT-4, designed to help clinicians evaluate drug-induced liver injury by parsing complex clinical histories and reference data. 📖 Read and share the article. ow.ly/n02B50YAXH5

In real-world peri−/premenopausal patients with HR+/HER2− MBC, ribociclib and palbociclib combined with endocrine therapy demonstrate comparable efficacy and tolerability. These findings support flexible treatment choice based on individual patients. buff.ly/4L2SyNW

Highly effective modulator therapy (HEMT) availability for the majority of PwCF has led to changes in pharmacotherapy regimens and clinical outcomes but has also been associated with adverse effects and drug interactions. buff.ly/3F16u8t

86% of the included studies demonstrated an impact by phenobarbital (PB) on outcomes, which were often related to therapeutic drug monitoring. Data suggest that PB does lead to clinically significant DDIs in multiple classes of medications. buff.ly/wqffkbt

Drug-induced liver injury (DILI) Consult demonstrates the potential of LLMs to assist clinicians in evaluating DILI. OPEN ACCESS: buff.ly/PvLw03h

The authors present predictive models that incorporate a comprehensive profile of disease and drug-related heterogeneity to stratify pediatric patients with LN by their likelihood of responding to MMF. buff.ly/WEY2Dcz