Pires Group: 🧪|🦠|🧫

We present "The mycomembrane differentially and heterogeneously restricts antibiotic permeation" a fantastic collaboration led by @siegristpalmore biorxiv.org/content/10.110…

Congratulations to our advisor Dr. Marcos Pires on being named a Dean's Research Fellow by the Graduate School of Arts and Sciences at UVA! as.virginia.edu/inaugural-clas… @ChemistryUVA #UVA #Pireslab #Science

Congratulations to 4th year graduate student Rachita Dash on receiving the Littleton Glover Endowed Graduate fellowship for the 2024-2025 academic year. @ChemistryUVA @___Rachita___ #UVA #UVAchemistry #UVA

Some of our graduate students learning about the latest advances in peptide science & presenting their work at the #37thEPS European #Peptide Symposium & 14th international peptide symposium in Florence, 🇮🇹. #peptide #EPS2024 #research #UVAchemistry #UVA

Our summer undergraduate researchers enjoying #ACSFall2024. #ACSDenver #UVAChemistry #UVA

Out in @AmerChemSociety chemical biology " A Chemical Approach to Assess the Impact of Post-translational Modification on MHC Peptide Binding and Effector Cell Engagement" pubs.acs.org/doi/epdf/10.10… Congratulations to all the authors.

Out in @PNASNews a collaboration led by David Weiss & Craig Ellermeier "Identification of a family of peptidoglycan transpeptidases reveals that Clostridioides difficile requires noncanonical cross-links for viability" pnas.org/doi/10.1073/pn… Congratulations to all the authors!

Out in @ChemMedChem a collaboration led by @TheveninLab "Selective Recruitment of Antibodies to Cancer Cells and Immune Cell-mediated Killing via In Situ Click Chemistry" Congratulations to all the authors. …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cm…

This study in #ACSInfectiousDiseases presents a method to assess the accumulation of antibiotics real-time in live bacteria using bioluminescence. @PiresChemBioLab go.acs.org/9dI

🎉Congratulations to third year graduate student Rachita Dash on winning the third year poster competition 🏆 @ChemistryUVA @___Rachita___

With our wonderful collaborators led by the Kana group in South Africa 🇿🇦 in @eLife " A modified BCG with depletion of enzymes associated with peptidoglycan amidation induces enhanced protection against tuberculosis in mice" elifesciences.org/articles/89157

Out in @BioconjChem A study focused on the intestinal microbiota entitled “Noninvasive Analysis of Peptidoglycan from Living Animals” a story led by @ScienceavecKarl. We thank our wonderful collaborators @RutkowskiLab and @jutraslab pubs.acs.org/doi/10.1021/ac…

Out in @FrontImmunol we present "Targeted acidosis mediated delivery of antigenic MHC-binding peptides" a story in a wonderful collaboration with @TheveninLab led by @Joeykelly510 frontiersin.org/journals/immun…

Check out our latest paper out in @ACS_Infectious led by @___Rachita___ We present a method to assess the accumulation of antibiotics, in real-time, in bacteria using bioluminescence! pubs.acs.org/doi/10.1021/ac…

Check out this recent preprint identifying a novel L,d transpeptidase in C. difficile. This collaboration was led by our fantastic collaborators form the university of Iowa pubmed.ncbi.nlm.nih.gov/38559057/

Check out our latest paper with our wonderful collaborators led by @AlisonCrissUVA group "Neisseria gonorrhoeae scavenges host sialic acid for Siglec-mediated, complement-independent suppression of neutrophil activation" Congratulations to the authors! journals.asm.org/doi/10.1128/mb…

🎉Congratulations to Rachita Dash and Liora Wittle for securing the 2024 stepped-up and newly-arrived UVA Chemistry departmental service awards! 🏆 @___Rachita___ @ChemistryUVA

🎓Congrats to our graduate students Joey Kelly and Karl Ocius for clinching the 2024 Hunt and Hecht UVA Chemistry departmental research awards! 🏆@joeykelly510 @ScienceavecKarl @ChemistryUVA

🎉Exciting news from our lab! Karl has been awarded the Merck Underrepresented Chemists of Color award🏆. This recognition is well-deserved and highlights Karl's dedication and talent. Congratulations, @ScienceavecKarl! 🌟@ChemistryUVA @Merck

Our latest manuscript "Measurement of Accumulation of Antibiotics to Staphylococcus aureus in Phagosomes of Live Macrophages" is live in @angew_chem dlvr.it/SzlfY0 Congratulations to all the authors! #UVAchemistry #Antibiotics #Permeability