Seth Lederman

With ~70 million Americans living, working, or vacationing in tick-endemic zones, Lyme disease is a public health crisis. There’s no FDA-approved vaccine or preventive therapy in the U.S, which Tonix hopes to address with our Phase 2 ready program. nytimes.com/2026/03/16/nyr…

Mpox is an emerging infectious disease that is now surfacing globally, including NY and the U.S. (with risk remaining low). Tonix is developing an attenuated investigational vaccine with the potential capability to protect against smallpox and mpox. abc7ny.com/post/first-kno…

I recently wrote in @ForbesCouncils about why better coordination, better science, and access to nonaddictive treatments could change the trajectory for millions of patients living with chronic pain. 📖 Read the full article #sponsored: forbes.com/councils/forbe… #ChronicPain

Watch our CEO @SethLederman, M.D., discuss our transformation into a commercial stage company with @ZacksResearch: ir.tonixpharma.com/news-events/ir… #Tonix #TNXP #Fibromyalgia #LymeDisease

Fibromyalgia is medicine’s “F-word," shorthand for this long-marginalized diagnosis. Yet 10M+ Americans live with it, and federal agencies are finally prioritizing infection-associated chronic conditions. We must translate better policy, education, and coverage into real care. My latest: @sethmlederman/note/p-189769068?r=bgve4&utm_source=notes-share-action&utm_medium=web" target="_blank" rel="nofollow noopener">substack.com/@sethmlederman…

Appreciated the opportunity to speak at #AmericanHealthcare about what it really takes to bring new medicines to patients. Drug development is long, complex, and expensive, but thoughtful regulatory reform, smarter trial design, and advances in data science can accelerate progress without compromising safety. Patients living with conditions like fibromyalgia deserve both rigor and urgency. youtube.com/watch?v=Jy5u2M…

Frida Kahlo’s paintings are more than symbols of resilience; they’re clinical portraits of untreated chronic pain. A century later, patients with fibromyalgia still wait years for diagnosis. Her story is a warning about what happens when medicine misreads pain. open.substack.com/pub/sethmleder…

Maine is facing record Lyme disease cases, and new prevention strategies are urgently needed. @newscentermaine featured Tonix’s work on a long-acting antibody approach to Lyme prevention, with expert insights from CEO @SethLederman. Thank you to @vivienleigh6 for covering this important topic! Read more: newscentermaine.com/article/news/h… #LymeDisease #PublicHealth #Biotech

Although it's often used as a punchline, Fibromyalgia is very real. I saw its debilitating symptoms firsthand in countless patients. Here is my latest article on how science can close the gap on chronic pain: sethmlederman.substack.com/p/no-hollywood…

Michael Jackson’s story is a reminder that chronic pain and sleep disorders have long been misunderstood and undertreated. In this article, I examine how fragmented care and risky prescribing patterns continue to fail patients Read article: bit.ly/4qWynYR Read my substack: bit.ly/4rAbhr3

#MichaelJackson's death wasn’t just a tragedy, it was a failure of how medicine treats chronic pain and sleep disorders. In RealClear Health, our CEO, @SethLederman examines fibromyalgia, fragmented care, and why symptom-chasing with risky drugs still persists today. We know better now. Care must change. More essays and reflections are available on Seth’s Substack: bit.ly/4rAbhr3 #ChronicPain #Fibromyalgia #SleepHealth #PainScience #NonOpioidCare #Tonix Read article: bit.ly/4qWynYR

Revisiting an early piece of mine that remains painfully relevant. “Suffering We Can Stop: The cruel choice between pain and addiction” explores how we can finally move beyond opioids and make nonaddictive treatments the standard of care. Read more: 🔗 bit.ly/48k3iYL #ChronicPain #Fibromyalgia #OpioidCrisis #PainManagement #BiotechInnovation

I’ve devoted my career as a physician, scientist, and biotech CEO to bringing better options to people living with chronic pain, fibromyalgia, PTSD, and other long-standing conditions. My first Substack post, “Suffering We Can Stop: The cruel choice between pain and addiction,” explores how we can move beyond opioids and deliver safer, more effective treatments for the millions living with chronic pain. I created this Substack to spark honest conversations about science, policy, and innovation and what must change if we’re serious about improving lives. I hope you’ll subscribe, join the conversation, and help shape a new dialogue around pain, progress, and compassion. sethmlederman.substack.com/p/suffering-we… #ChronicPain #Fibromyalgia #Science #HealthPolicy

"Suicide is a national epidemic. We need to treat it like one." Op Ed in Washington Post by Dr. Jonathan Javitt wapo.st/2KW5yMk

Why the word ‘vaccine’ is probably all wrong sciencemag.org/news/2017/10/w…