The Sellers Lab

14 posts

The Sellers Lab

The Sellers Lab

@TheSellersLab

The Sellers Lab leverages the link between genetic alterations & cancer dependencies to *Elucidate new therapeutic hypotheses *Develop novel therapeutics

Cambridge, MA เข้าร่วม Ağustos 2021
26 กำลังติดตาม534 ผู้ติดตาม
The Sellers Lab
The Sellers Lab@TheSellersLab·
We're thrilled about the publication of a new paper by @liangc_science in @NatureGenet! Take a look below for a link to the article.
Liang Chang@liangc_science

Excited to share that my main PhD paper @TheSellersLab is published on @NatureGenet ! We found that conditional pathway activation is a new class of cancer synthetic lethality, opening new opportunities for future cancer therapeutics. A Twittorial 🧵👇 nature.com/articles/s4158…

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The Sellers Lab
The Sellers Lab@TheSellersLab·
New publication from the Sellers lab! We benchmarked 10 CRISPR libraries for dual-gene knockout screens, and a spCas9 system with different tracrRNAs consistently show superior performance. Promising strategy for future paralog & gene interaction screens! go.nature.com/3L1jZJn
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The Sellers Lab
The Sellers Lab@TheSellersLab·
Congratulations to all who worked on the paper!
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The Sellers Lab รีทวีตแล้ว
Liang Chang
Liang Chang@liangc_science·
From MRTX849/Adagrasib (G12C inhibitor) to MRTX1133 (G12D inhibitor released today), so impressive to see that the switch II-pocket-targeting skeleton held up, and the elegant tweakings around targeting G12D. Exciting time for drugging KRAS!
Liang Chang tweet media
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The Sellers Lab
The Sellers Lab@TheSellersLab·
Happy Friday and Hello October. What are you looking forward to this month? (JM)
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The Sellers Lab
The Sellers Lab@TheSellersLab·
@WilliamKimMD Bill will be on shortly, but I will definitely tell him hello for you! -JeM
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The Sellers Lab
The Sellers Lab@TheSellersLab·
Good Morning and Happy Wednesday! Thank you for following, we're looking forward to chatting with you!
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The Sellers Lab
The Sellers Lab@TheSellersLab·
Since we're "newbies" to Twitter, we'd appreciate some ideas on who we should follow via @'s or #(hashtags). Who are some of your go-to's?
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The Sellers Lab
The Sellers Lab@TheSellersLab·
Good Morning! We are the Sellers Lab housed in Cambridge at the @broadinstitute! We look forward to chatting and interacting with everyone!
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ค้นพบ

@liangc_science @NatureGenet @Takahiro_Ito3 @mchljyng @KathleenMulvan4 @WilliamKimMD @broadinstitute @elonmusk