Valentina

Si te sabes está canción necesitas: Omeprazol, vitaminas, Ibuprofeno, colágeno y omega 3

Hoy no voy a insistir.

five studies I would put at the top of the ACC.26 March 28–30, 2026, in New Orleans 1.CHAMPION-AF — primary results comparing left atrial appendage closure vs oral anticoagulation in patients with atrial fibrillation. 2.STEMI-Door to Unload — results of primary left ventricular unloading in anterior STEMI without cardiogenic shock 3.Spironolactone in the Treatment of Heart Failure 4.TAVI Without Routine PCI — a randomized trial testing transcatheter aortic valve implantation without routine percutaneous coronary intervention. 5.Discontinuation of β-blocker Therapy in Stabilized Patients After Acute Myocardial Infarction #ACC26 #Cardiology #MedTwitter #CardioTwitter #HeartHealth #Healthcare @JACCJournals @ACCinTouch @DrMarthaGulati @hvanspall @BiykemB @ankeetbhatt @ShelleyZieroth @Hragy @cardioceptor accscientificsession.acc.org

Nadie te advierte que la vida adulta es básicamente preparar pechuga de pollo de diferentes maneras.

Il richiamo del vaccino contro la pertosse SI DEVE FARE OGNI 10 ANNI. (dalla @Gazzetta_it )

#Amiloidosi cardiaca #ATTR: il trattamento evolve. Tafamidis, acoramidis, e vutrisiran, insieme a SGLT2i e MRAs per migliorare prognosi e qualità di vita #cardiologianegliospedali 👉 cardiologianegliospedali.it/novita-nel-tra…

All the explanations I’ve heard today for the negative CLOSURE-AF result—some so strained they’re almost impressive. 1) The devices were “outdated” and therefore responsible for excess complications (the usual argument that things only go wrong elsewhere). 2) DAPT was used after LAAO, which is now said to be obsolete because of bleeding concerns compared with DOAC-based strategies (a claim that is often repeated, less often demonstrated). 3) Stroke rates were similar, so the signal is attributed mainly to bleeding and procedural issues—as if that were a minor point. 4) The composite endpoint is criticized for mixing different mechanisms, although if anything it should have favored non-inferiority. 5) The early phase of enrollment is invoked to argue that complications are not representative of current practice (again, complications seem to belong to others). 6) And then there are the usual remarks about loss to follow-up, crossovers, and lack of blinding. What seems to be missed in this accumulation of arguments is straightforward: the burden of proof lies with LAAO, not with the control arm. The issue is the strength of the evidence supporting LAAO, not medical therapy, which remains the reference standard.

Esempio lampante di come non siano solo i giovani a non saper usare i social e a non avere educazione digitale. Esiste il concetto di diritto alla disconnessione per cui si scrive a collaboratori, professionisti e colleghi a orari decenti.

Come possono i centri di secondo livello accedere alla #cardiogenetica, privilegio di pochi? L’innovativa esperienza di Piacenza raccontata da Di Spigno et al. giornaledicardiologia.it/archivio/4650/…

@RGthedoctorisin Ho letto i commenti e non ho niente da dire. Mi meraviglio ancora di più. Una battaglia persa. Però ringrazio u miei pazienti che mandano email ❤️

"Buongiorno dottoressa, mi dispiace che ho dovuto spostare il nostro appuntamento" "Non si preoccupi signora, magari la prossima volta però non lo faccia via whatsapp alle 3.30 del mattino" "Erano le 3.30?" "Sì signora" "Vabbè ho pensato che leggeva quando si alzava" >>

2026 ACC/AHA Dyslipidemia Guideline — Key Points 1️⃣ LDL targets are officially back The 2018 guideline emphasized percentage reduction. The 2026 guideline reintroduces explicit LDL goals. Typical targets: Clinical settingLDL goal High ASCVD risk primary prevention<70 mg/dL Secondary prevention<55 mg/dL Severe hypercholesterolemia<100 or <70 mg/dL depending risk Percent reduction remains important: •Moderate statin → 30–49% reduction •High-intensity statin → ≥50% reduction This hybrid strategy combines relative reduction + absolute targets.  2️⃣ Universal Lp(a) measurement For the first time: ➡ Measure Lp(a) at least once in all adults Thresholds: •≥50 mg/dL (125 nmol/L) → risk-enhancing •≥100 mg/dL (250 nmol/L) → ~2× ASCVD risk Management: •Intensify LDL lowering when elevated.  3️⃣ ApoB enters clinical decision making ApoB testing is recommended when: •triglycerides elevated •diabetes •very low LDL levels •suspected residual risk It helps identify atherogenic particle burden when LDL appears controlled.  4️⃣ New risk calculator: PREVENT equations The guideline replaces Pooled Cohort Equations. New system: PREVENT-ASCVD Risk categories: Risk10-year risk Low<3% Borderline3–5% Intermediate5–10% High≥10% Used for ages 30–79.  5️⃣ CAC scoring becomes central CAC is strongly integrated in treatment decisions. Key recommendations: •CAC = 0 → therapy can be deferred in selected patients •CAC ≥100 → statin recommended •CAC ≥300–1000 → aggressive LDL targets Also important: ➡ Incidental CAC on non-cardiac CT should influence treatment decisions.  (This has big implications for CT imaging specialists.) 6️⃣ Earlier treatment philosophy Major conceptual shift: Reduce lifetime exposure to atherogenic lipoproteins. Treatment may start earlier if: •LDL ≥160 mg/dL •family history •subclinical atherosclerosis Even in relatively low 10-year risk patients.  7️⃣ Expanded drug arsenal Guideline integrates new agents: DrugClass PCSK9 inhibitorsmonoclonal antibodies InclisiransiRNA Bempedoic acidACL inhibitor EvinacumabANGPTL3 inhibitor OlezarsenapoC3 inhibitor These are used to reach LDL goals when statins insufficient.  8️⃣ Dyslipidemia definition expanded The guideline is renamed “Dyslipidemia” rather than “Cholesterol” to reflect broader biology: Includes: •LDL •triglycerides •remnant particles •Lp(a) ASCVD risk is considered apoB-lipoprotein driven, not LDL alone.  9️⃣ New emphasis on subclinical atherosclerosis Patients with: •CAC ≥100 •incidental coronary calcification •imaging evidence of plaque should receive lipid-lowering therapy even without clinical ASCVD.  🔟 Hypertriglyceridemia management updated Important additions: •apoC3 inhibitor olezarsen for familial chylomicronemia •statins remain first-line for ASCVD prevention •triglyceride therapy mainly for pancreatitis prevention.  💡 Big conceptual shifts The 2026 guideline essentially reflects three paradigm changes: 1️⃣ Lifetime exposure model Risk depends on years of exposure to apoB lipoproteins. 2️⃣ Imaging-guided prevention Subclinical disease → treatment. 3️⃣ Particle-based risk LDL alone is insufficient → ApoB and Lp(a).

Recién salidas del horno, las Guías AHA 2026, de Dislipidemia. Algunos cambios importantes: 🟢Se eliminan las calculadoras de cohortes, y ahora se prefiere PREVENT. Se reduce también el umbral para iniciar estatinas (algo agresivo a mi parecer): riesgo a 10 años de ≥3% 🟢 Adiós a Friedewald: para la estimación del LDL-C, las ecuaciones de Martin/Hopkins o Sampson/NIH son ahora la recomendación preferida. 🟢 El retorno de Metas absolutas. Muy alto riesgo: LDL <55 mg/dL. Prevención primaria (Riesgo alto ≥10%): LDL <70 mg/dL. Riesgo intermedio 5-<10%: LDL <100 mg/dL 🟢 Se indica medir Lp(a) al menos una vez en la vida en todos. +50 mg/dL aumentan el riesgo cardiovascular relativo en aproximadamente un 40% 🟢Se instaura el modelo CPR (Calculate, Personalize, Reclassify). Si después hay incertidumbre, Score de Calcio (Reclassify) es el desempate. CAC = 0: sin estatinas. Voy a revisarlas a fondo para actualizar las apps (memodi.memodiapp.com/apps). Pueden bajar el PDF en el canal (t.me/memodiappartic…).

@Devabole Libri musicali che ai bimbi piacciono e aiutano lo sviluppo intellettivo

Cosa consigliate di regalare per la nascita di una neonata?

¿Si aumentan los pacientes en la Sanidad Pública no se debería aumentar también el personal sanitario? Pregunto.

Lettura consigliata

🌐 Farmaci orali per il diabete di tipo 2 e rischio di fibrillazione atriale: vantaggio degli inibitori SGLT2 📱cardiolinksalute.it/articolo/18377… #CardioLink #Salute • Area Salute per #pazienti 👨‍👩‍👧‍👦 Comprendere la salute, con parole semplici ❤️

Vaccinate i vostri figli contro HPV: il vaccino è sicurissimo ed estremamente efficace nel proteggerli dal cancro.

@FrancyontheMoon @BlastometroTW Che belle risposte chiare e pacate che hanno scritto. Un minimo di giustizia

Voci di paese vs addetti ai lavori. Ovviamente la voce di paese - basata su fantomatiche confessioni di fantomatico personale - vale di più. @BlastometroTW cosa dite, un piccolo blast me lo riconoscete?

Para quien no sabía: 1.Los médicos duermen. 2. Los médicos se alimentan. 3. Los médicos tienen familia. 4. Los médicos precisan de dinero (también pagan cuentas). 5. Los médicos no examinan pacientes por teléfono. 6. Los médicos no son videntes ni magos. 7. Los médicos dejan de ser médicos en reuniones de familia y en fiestas. 8. Los médicos también tienen vacaciones. 9. Los médicos también se enferman. Los médicos son seres humanos como usted.

Cómo sobrevivir en Colombia (manual básico no oficial) 1. Jamas tomes taxi en la calle. ❌🚕 2. No tengas tus ahorros en el banco más famoso. “muy grande” no siempre significa “muy confiable”. 🏦💳💸 3. Aunque el semáforo esté en verde, frena. Aquí la norma es: “confía, pero verifica”. Especialmente con motociclistas. 🚦🛵⚠️ 4. Si estás en la calle, no contestes el celular. Las llamadas pueden esperar. El susto no. 📵 5. No lleves cosas lujosas. El bajo perfil es el nuevo lujo. Cuál seria tu consejo para sobrevivir en Colombia :