Creatine is one of the most studied supplements, and still misunderstood.
👉 Doesn’t harm kidney function in healthy individuals
👉 Raises creatinine ≠ kidney damage
Beyond muscle: brain, metabolism, aging.
Mild side effects at most.
Full breakdown:
drkarafitzgerald.com/2026/03/20/cre…
Rethinking Alzheimer’s risk 🧠 APOE4 ≠ the whole story. New research suggests APOE3 may not be “neutral,” and genetics may play a larger role than modeled. The future? Genetics + lifestyle.
DOI: 10.1038/s44400-025-00045-9
Infrared sauna therapy is often discussed as a relaxation or detox practice. But emerging research suggests that heat exposure may influence several biological pathways relevant to longevity.
drkarafitzgerald.com/2026/03/12/inf… for the full blog.
Your tongue is as unique as a fingerprint — scientifically proven! 👅
A study published in the Journal of Forensic Dental Sciences (PMID: 28123263) highlights that no two individuals have the same tongue print, not even identical twins!
When extrinsic mortality is removed, genetics may explain ~50% of lifespan variation. A new twin study in Science suggests intrinsic aging is far more heritable than previously thought. Genes aren’t destiny—but longevity medicine may soon include polygenic risk for aging.
Spring forward. Biology pushes back. ⏰🧬 Even a 1-hour shift in circadian timing can disrupt sleep, inflammation signaling, glucose regulation, and cardiovascular risk.
#CircadianRhythm#Longevity
Sleep protects your brain. 🧠💤
During deep sleep, the brain’s glymphatic system clears metabolic waste, including beta-amyloid linked to Alzheimer’s.
Prioritize sleep to protect cognitive function and brain health.
Epinutrients in leafy greens, herbs, berries, olive oil, and tea help regulate inflammation, mitochondrial function, DNA methylation, and cellular repair.
Food isn’t just fuel. It’s biological instruction.
#Epigenetics#Longevity#FoodAsMedicine
Chronic stress is linked to shorter telomeres, increased inflammation, and faster epigenetic aging. One study found high-stress women had telomeres equivalent to ~10 extra years of aging.
Regulation isn’t optional. It’s longevity medicine. 🧬
We’re living longer, but nearly 20% of life is spent sick, with serious illness often starting around 63. The Younger You approach uses epigenetics + diet & lifestyle to compress morbidity:
✔️ More healthy years
✔️ Fewer years managing disease
Simple. Sustainable. Human.
Seafood can be powerful medicine or an unnecessary toxic exposure.
The key? Choosing fish rich in omega-3s without excess mercury or contaminants.
I created a free, practical guide to help you make safer seafood choices for you & your family.
👉 drkarafitzgerald.com/safe-seafood-c…
Researchers studying “super-agers” found fewer Alzheimer’s risk genes and more protective variants. Sounds like luck, until epigenetics enters the chat.
Genes set risk. Biology decides expression.
🧬 Genetic risk ≠ destiny.
DOI: 10.1002/alz.71024
“You need to become the director of the orchestra of your own health.” That idea sits at the heart of my recent conversation with Sergey Young. We talk about taking agency in your health, coordinating the basics so your biology works with you, not against you.
Walk this way to a better brain 🧠🚶♀️
A study found that walking 40 min, 3x/week increased hippocampal size by ~2% and improved memory in healthy older adults—effectively reversing 1–2 years of age-related brain loss.
Study suggests melanocyte stem cells respond to DNA damage by entering senescence and losing pigment, a trade-off that may reduce melanoma risk. Some aging features may reflect tumor-suppressive biology, not simple decline. DOI: 10.1038/s41556-025-01769-9
This should concern every parent, clinician, and educator.
In a large JAMA study (6,500+ kids), increased social media use ages 9–13 was linked to small but measurable declines in memory, language, and cognition just 2 years later.
doi:10.1001/jama.2025.16613
When sleep is short, physiology shifts fast. One counterintuitive buffer: 10 minutes of HIIT. It can boost cerebral blood flow, glucose control, and temporarily restore cognitive performance. A bridge, not a substitute for sleep.
#SleepHealth#HIIT#FunctionalMedicine
One of the clearest mechanistic links yet between EBV and lupus. New Science Translational Medicine data show EBV can reprogram autoreactive B cells, amplifying immune dysfunction, not just triggering flares. Important for how we think about autoimmunity.
PMID: 41223250