Dr Mark Connor

New study shows that (−)-Cannabichromene activates CB2 receptors 🧠, while (+)-CBC does not. Both enantiomers activate TRPA1 receptors, but (−)-CBC is the more effective isomer for targeting cannabinoid receptors. 📄 Read more: buff.ly/3YabnZo 🌿 #Cannabinoids #CBC

@forensictoxguy How about a prime example ?

@lavietidhar For what ? Making random strangers on the other side of the world happy … enough ?

So many novels, and for what? I should retire.

The colours are so complimentary

@blak_kar, Actually, not too far from where I think you are (Minjerribah)

@christophestove @IATDMCT @GentCongres How do you remember what all the acronyms stand for ? And where Ghent is ? Is not simply an idea of home ?

Superglad & excited to announce that #IATDMCT2028 will be held in ... ... ... #GHENT! Line-up of the upcoming @IATDMCT meetings: #IATDMCT2025: Singapore, Sep 21-24; #IATDMCT2026: Rennes, Sep 2026; #IATDMCT2027: Montreux, Oct 3-6 2027; #IATDMCT2028: Ghent, Sep 17-20 2028.

@Pharmechanic @zenbrainest @brightmindsbio But well done getting to Phase 2, hope it works out for the patients !

@zenbrainest @brightmindsbio Cool! Thanks Bryan. Is there in vitro pharmacology published on this? Is the idea that it will be better for chronic dosing because the reduced arrestin recruitment will minimize desensitization? (I’m looking for an example of this for a presentation.)

The very first G protein biased, subtype-selective serotonergic agonist now in Phase II! @brightmindsbio

@Pharmechanic @zenbrainest @brightmindsbio hesitate to enter conversation ... but what about cellular/circuit adaptations to chronic G protein activation ... or is that a feature, not a bug ? ... returns to 199X and thinks about opioids ...

Pretty great for an MRes … can’t wait to see what is next !

Exciting to see this project move into the construction phase. It’s a complex beast, but will build critical capacity for NSW and Australia in this rapidly emerging technology

@BritPharmSoc So much for the Common people … assume you will be sorted for E’s & wizz ?

Alternative britpop puns: 🎟️ Tickets will be gone in a #Blur ! 👥 Per-#Suede your friends to come! 🤔 #DoYouRememberTheFirstTime you came to a BPS event? 😬 Erm, something by #TheCure?

Some might say that you could save up to 50% on your #Pharmacology2024 tickets when you book by 29 October 2024. 👀 Don't look back in anger - secure yours today: ow.ly/lKbH50T7eoN 😛 #Oasis #OasisReunion #Oasis2025 #Pharmacology

Glad to finally share that (-)- CBC is the active CB2 isomer but both CBC isomers are active at TRPA1

@TheCannabisGuyy @MariJSantiago @YouthSpark

New paper from Mike Udoh & our colleagues at Baymedica, identifying the CB2-active isomer of CBC ... watch this space for more chiral surprises ... Activation of CB2 Receptors by (−)-Cannabichromene but Not (+)-Cannabichromene | C&CR, liebertpub.com/doi/10.1089/ca…

@lewischewis I have not got past the summary … it seems intense, and obtuse ???

@markfrommacq fine, thank you Mark! Hope you are enjoying the blog!

new blog: querying espaloma charge from another conda/mamba env using a local flask server. Avoid messing up your conda env! ljmartin.github.io/blog/23_flask_…

@Nnedi What with that and the Kookas, is it time for a visit to see them in their natural environment ... wouldn't even have to leave Sydney suburbia to see both (or not see the frogmouths, they are pretty hard to spot)

I’ve been too tired to really post about #WorldCon and what it’s been like to be a Guest of Honor. It’s been *wonderful* and hectic. A lot to process. When I get home, I’ll post more. Meantime, here are 2 frogmouths I saw at the Scottish Owl Centre pretending to me wood: