jm
222 posts


@mutemedia11 @Matt_Pinner Think the last four letters spell ball
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@lady_valor_07 Always pay as much tax as possible so your government can provide best possible service to you and other citizens
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@thechosenberg Kratom didn't do shit for me or other friends who have taken it. Placebo effect.
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@mutemedia11 @mutemedia11 Creep? Nah — cop was adulting: real talk, pinky promise, lesson dropped. Kid stayed respectful, got grace. That's good policing, not creepy. Back the blue 🇺🇸🚔
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The mouse study used monthly oral psilocybin: 5 mg/kg initial dose, then 15 mg/kg. For ~84 kg (185 lbs), that's roughly 420 mg then 1260 mg monthly. But this is experimental animal data—no human dosing established for anti-aging. Psilocybin is regulated; consult a doctor for personalized, legal advice.
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Psilocybin made human cells live 50% longer.
A new study has uncovered surprising anti-aging potential in psilocin—the active metabolite produced when the body breaks down psilocybin, the psychoactive compound found in magic mushrooms.
In laboratory experiments, researchers exposed two human cell lines (skin fibroblasts and fetal lung fibroblasts) to a 100 μM concentration of psilocin. The results were striking: lung cells took 57% longer to reach replicative senescence (the point at which cells permanently stop dividing and accumulate damage), while skin fibroblasts extended their replicative lifespan by 51%.
These findings suggest psilocin may slow fundamental cellular aging processes, possibly by lowering oxidative stress, enhancing DNA-repair pathways, supporting mitochondrial health, or dampening chronic inflammation—mechanisms that overlap with those targeted by leading experimental longevity drugs.
The benefits extended beyond cell culture. In aged female mice (19 months old at the start, equivalent to approximately 60–65 human years), a single monthly dose of psilocybin dramatically improved outcomes. After 10 months of treatment, 80% of the psilocybin-treated animals remained alive, compared with only 50% of untreated controls. Treated mice also displayed markedly fewer visible signs of aging, including reduced fur loss and graying.
This research marks the first direct demonstration that psilocybin/psilocin can influence biological aging itself, rather than solely producing psychological effects. The authors emphasize that the study used relatively conservative dosing and are now advocating for follow-up work with higher or more frequent administration, detailed assessments of immune, metabolic, and cognitive function, and investigations into whether the extended lifespan corresponds to genuine improvements in healthspan and quality of life.
["Psilocybin treatment extends cellular lifespan and improves survival of aged mice." npj Aging, 2025]

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Just fired my best employee today
She was with us for 7 years
Perfect performance reviews, clients loved her
"Our compliance officer found something on your laptop" I told her
She went pale
"A VPN. You have been accessing American websites"
She started shaking
"It was just Netflix. The European catalog doesn't have the shows I want"
I couldn't believe what I was hearing
"So you bypassed European content regulations because you wanted more options?"
"Please. I'll delete it, it was only once and after work hours" she begged me
"The data already crossed American servers. There's no undoing that"
I handed her the termination papers and called for security to escort her out
I promoted the compliance officer the same day
That's the kind of initiative we need
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@JOKAQARMY1 This is not real. This is AI. You can tell due to the blurry parts that pop up — they removed Sora AI watermarks.
@grok was wrong when answering another comment.
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