Carlos Reding

Well well well the paper is finally out. A proof-of-concept study where I explore the effect on drug efficacy against a targeted baterium of other microbial species growing alongside. MICs in the presence of these neighbours is predictable (qualitly) 🤓 nature.com/articles/s4370…

@javiernegre10 Por todo lo que ha hecho mal, cuando ha importado ha puesto los cojones sobre la mesa. Aunque sea por motivo electoral, lo ha hecho y lo sigue haciendo. La alternativa es muy triste, ser un paria. Si sólo un partido de derechas hubiera apoyado Sánchez contra la guerra e Israel...

4 años más de Sánchez pueden significar tirar por la borda 700 años de reconquista. Pueden ser el punto de no retorno. El ser España o no ser. El que España sea española o los españoles seamos minoría en España. Eso nos jugamos.

@RafaMorgan64 * I get not _all_ Americans voted like that, and it's unlikely the next nutter would receive such support... but just enough to get them over the line is bad enough. No country is free from these circumstances, luckily most don't believe they own the world, but there's always one

@RafaMorgan64 I don't think that will happen. Trump was elected twice, in non-consecutive elections. There is no guarantee a different deranged person will be elected. American are of course entitled to do so, but the rest of us don't have to suffer them. So at the very least I'd be cautious.

Americans are increasingly aware that the European Union isn't against them; it's against Trump. As soon as Trump is out of power, the European Union will open its doors as it always has. I don't know what the rest of the world will do; too many countries are already angry with the USA. Trump's legacy will be a huge cesspool of accusations and recriminations. Eighty years wasted.🇪🇺

@Samaytwt Buy a laptop you can upgrade instead.

unpopular opinion: never buy a 16GB RAM laptop in 2026. you’ll regret it within a week

@PrinceEwa5 @BRICSinfo Because it didn't

@BRICSinfo I can remember the UK refused to grant access to the US to use their military base. So why is the UK preparing for war?

JUST IN: 🇬🇧 UK is working on a major plan to prepare the country for war.

@slifante Con que manden mensajes a números marroquíes diciendo que Cristiano Ronaldo va a entrenar en el campo del UD Melilla, ya dan por culo.

Vosotros creéis que va a financiar a algún grupo terrorista para atentar en España? Es el estilo israelí. Lo digo en serio.

@Nosoyheimdall El balón de oxígeno se lo han dado los patriotas de cartón. Sánchez lo ha clavado aquí, y lo sigue clavando. Cuando la oposición tiene una actitud que insulta, servil hasta el punto de no defender a nuestros militares... pues toca lo que toca. Paradojas de la vida.

Con la falsa dicotomía en el discurso por bandera, Netanyahu acaba de dar el mayor balón de oxígeno a Sánchez y a la psoe, les ha dado justo lo que querían. Y ahora a seguir con el circo.

@mericcolo @krishdotdev Or the calculator, or any electron app, or... We'll maybe Tahoe is just a PoS

@krishdotdev Just avoid using apps from Microsoft and it’ll be fine

Memory leaks on macbook neo is now often.

@FanlessTech Then why does my house get dusty if I haven't got any fan?

With no fans to draw in dust, fanless PCs stay spotless on the inside

@aakashgupta The winner here is Apple ofc: users have to preemptively pay for a SSD of more capacity since it cannot be upgraded down the road from a other provider.

@aakashgupta Oh boy you got it all wrong. Redundancy in mac apps is rampant, precisely because everything is self contained. Promoting sloppy software - conveniently you cannot upgrade your SSD in a mac. Linux gets it right: a library that's needed by different programs is installed once.

Let me explain exactly why Apple still uses drag-to-install in 2026, because the joke here accidentally proves Apple right. A macOS .app is a single self-contained folder disguised as a file. Every dependency, every framework, every resource lives inside it. Drag it to Applications, it works. Drag it to Trash, it's gone. No registry entries. No leftover DLLs. No uninstaller that misses half the files. Windows installers scatter fragments across Program Files, AppData, the registry, system32, and a dozen temp directories. Uninstalling a Windows app is an archaeological dig. Five years later you're still finding config files from software you forgot you owned. Linux is worse. Dependency hell is so common they named it. Entire package managers exist to solve the problem of "I installed something and now nothing else works." Flatpak and Snap were invented specifically to copy what macOS bundles already did natively. The macOS bundle architecture came from NeXTSTEP in 1989. Steve Jobs brought it to OS X in 2001. The core design hasn't changed because the core design was correct. An app is a folder. Installation is a copy. Removal is a delete. Three operations that map perfectly to how humans already think about files. The drag-to-install window with the arrow isn't lazy UX. It's the entire thesis of the system made visible. You are literally just moving a folder. There is no "installation" step because there's nothing to install. The app is already complete. Every other OS eventually tried to get here. Windows got MSIX. Linux got Flatpak. Mobile figured it out from day one because phones shipped after Apple proved the model. The pattern everyone else converged toward is the pattern this tweet is calling outdated. The funniest part: the app being dragged in that screenshot is Claude. An AI that can write code, analyze documents, and reason about complex systems. And the most advanced step in getting it onto your machine is holding down a mouse button and moving your wrist two inches to the right. That's not a design failure. That's a 37-year-old architecture so good that the most sophisticated software on earth still ships inside it.

@valigo Microsoft also received a lot of heat with Vista for asking for password for virtually anything - change a setting, install a program... macOS is like that on steroids, and no complaints either. Users fully institutionalised.

Wait, so you can't install xcode without having an apple account? And people are bitching about Windows requiring Microsoft account, but not about this? Are Apple users just all cucks? What is going on? Or am I being stupid? On a side note, what's the meta of installing software on macs now? Do people still use homebrew? I remember it sucked 8 years ago.

@heyshrutimishra Add warming up oceans to the results. The heat has to go somewhere.

China deployed a 1,300-ton data center on the ocean floor off the coast of Hainan. No cooling towers or air conditioning. Just cold seawater doing the job for free. The result? Cooling costs drop from ~50% of total energy to under 10%.

@AGONbyAOC I'll believe when I see it

We’re clearing out our EU/US warehouses and found a batch of extra monitors. And we want to give them to YOU. Comment if you want one ⤵️

FFmpeg is moving to Rust 🦀 Our use of C and Assembly in FFmpeg has been an unacceptable violation of safety. FFmpeg will be running 10x slower - but we're doing it for your safety. All your videos will appear green - safety first, working software later.

@abhishek Any "windows" laptop with Linux in it.

This MacBook, bought 10 years ago, has been working like new even today. 👀 Tell me which Windows laptop can last this long, and I will wait. 🫠

@aakashgupta Honestly that's not on Altman. The companies are so eager to think they're going to make big bucks they don't even bother reading what they're signing. Almost like 2008, except the scammer is not a company but a person. Elisabeth Holmes and Theranos were thrown the book for less.

The timeline on this is genuinely insane. October 2025: Sam Altman flies to Seoul and signs simultaneous deals with Samsung and SK Hynix for 900,000 DRAM wafers per month. That's 40% of global supply. Neither company knew the other was signing a near-identical commitment at the same time. Those deals were letters of intent. Non-binding. No RAM actually changed hands. But the market treated them as gospel. Contract DRAM prices jumped 171%. A 64GB DDR5 kit went from $190 to $700 in three months. December 2025: Micron kills Crucial, its 29-year-old consumer memory brand, to reallocate every wafer to AI and enterprise customers. The company explicitly said it was exiting consumer memory to "improve supply and support for our larger, strategic customers in faster-growing segments." Translation: the AI demand signal was so loud that selling RAM to PC builders stopped making financial sense. March 2026: Google publishes TurboQuant, a compression algorithm that reduces AI memory requirements by 6x with zero accuracy loss. Cloudflare's CEO called it "Google's DeepSeek." The entire thesis that AI would consume infinite memory forever just got a six-month expiration date on it. Same month: OpenAI and Oracle cancel the Abilene Stargate expansion. The $500 billion data center vision that justified the RAM deals couldn't survive its own financing terms. Bloomberg attributed the collapse partly to OpenAI's "often-changing demand forecasting." MU is now down ~33% from its post-earnings high. Revenue up 196% year over year, EPS up 682%, and the stock is in freefall because the company restructured its entire business around a demand signal that came from non-binding letters and is now being compressed out of existence by a research paper. Micron bet the consumer division on Sam Altman's signature. The signature was worth exactly what the paper said: nothing binding.

@DiegoRoyet41761 Yo diría que Manolo tiene por lo menos 40

Cuantos años le ponen a mi princesa?

Me voy a casar con una Ucraniana para mejorar la raza, ¿algún consejo que puedan darme mi gente?"...😎

@DiegoRoyet41761 Mordisquitos

Un buen nombre para este perro ?

@isfjcutebear Kenji Kawai

Without googling name a famous Japanese person