spacealt
9K posts









No wonder you're confused about what to eat. The two biggest dietary guideline organizations in the US just released opposing recommendations (American Heart Association vs. USDA). Here's where the two guidelines agree, disagree, and what the science says. 🧵


61% of astronauts on ISS missions reactivate dormant viruses while in outer space (e.g. EBV, VZV, CMV) -- and the full immune cascade driving this still isn't fully understood What's exciting is the Artemis II crew is now flying with personalized organ chips built from their own bone marrow cells, which could finally help us understand how and why these viruses get reactivated at the cellular level I post a lot about immune function and mitochondrial health -- and I believe the viral reactivation in this case is directly related to something going wrong with the body's energy systems, specifically to the mitochondria Microgravity triggers oxidative stress, damages mitochondrial function, and suppresses immune cells. The NK cells and T-cells that normally keep viruses in check essentially shut down What makes this interesting beyond space is that a similar pattern shows up in ME/CFS, Lyme, and long COVID patients Same thing here, mitochondrial dysfunction, immune suppression, and dormant viruses wake back up because the body's ability to keep them suppressed breaks down Maybe with this chip we'll be able to pinpoint the exact moment the body's defenses goes haywire, or maybe we'll find a better biomarker which can point a specific mechanism causing the immune dysfunction Two NASA-funded health studies I'm tracking (highlighted in yellow) - Blaber Lab (mitochondrial dysfunction in spaceflight) - Dr. Iyer (mitochondrial oxidative stress) Both seem like they're building toward the same question from different angles




Reducing health to just lab work was such a travesty and crime










