ule_lab

59 posts

ule_lab

ule_lab

@ule_lab

Welcome to the RNA networks lab! @TheCrick and @UKDRI at King's in London and @kemijski in Ljubljana 🇪🇺

เข้าร่วม Ağustos 2020
307 กำลังติดตาม899 ผู้ติดตาม
ule_lab รีทวีตแล้ว
gagneurlab
gagneurlab@gagneurlab·
Honoured to have written this review with Jernej Ule’s lab on the splicing code, spanning modeling, mechanisms and its implication for therapeutics designs. Wonderful teamwork.
Nature Reviews Genetics@NatureRevGenet

From computational models of the splicing code to regulatory mechanisms and therapeutic implications go.nature.com/4gPju63 #Review by @tiny_captain, @OscarWilkins16, @nils_f_wagner, Julien @gagneurlab & Jernej @ule_lab @HelmholtzMunich @TU_Muenchen @TheCrick @KingsCollegeLon

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Miha Modic
Miha Modic@paraspeckle·
How can cellular signalling swiftly & selectively remodel the transcriptome to drive biological transition? How this switch is orchestrated has been a mystery... 🧵 nature.com/articles/s4159…
Miha Modic tweet media
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Miha Modic
Miha Modic@paraspeckle·
An opinion piece on how phosphorylation of intrinsically disordered domains selectively alters global protein–RNA binding profiles. sciencedirect.com/science/articl…
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UK Dementia Research Institute
💡Opportunity for a Lab Technician to join Prof Jernej Ule's lab (@ule_lab)! Join Dr Owen G. James (@owengwydz) and a team of researchers working on the roles of ribonucleoprotein complexes (RNP) and their defects in neurodegeneration👉buff.ly/48r4nei
UK Dementia Research Institute tweet media
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ule_lab@ule_lab·
@liamfaller Congrats Liam and team, really impressive how you could unravel ribosome heterogeneity from Ribo-seq data so well! This will be increasingly useful as more data emerges.
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Oscar Wilkins
Oscar Wilkins@OscarWilkins16·
Great opportunity to join our team (@FrattaLab) working on an innovative new gene therapy for ALS/FTD. A mix of novel computational (incl. new machine-learning approaches), molecular & cellular biology, all with a real therapeutic aim. Get involved! Link: tinyurl.com/bddjtjvc
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Charlotte Capitanchik 🌙
Charlotte Capitanchik 🌙@tiny_captain·
Wahoo!! Read on for some v. cool insights into how YTH proteins function... in yeast the lone YTH protein is loaded at chromatin & travels to cytoplasm where it helps to couple decay of targets to active translation 👯‍♀️
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Faraz K Mardakheh
Faraz K Mardakheh@FKHM·
Check out our latest preprint entitled “An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene”, out now on @biorxiv: biorxiv.org/content/10.110… (1/9)
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ule_lab@ule_lab·
This is the first manuscript fully done by the Ljubljana satellite of the RNA networks lab! Originated by Aram @amalietti , an incredible software developer who wrote the code, and then taken over by Klara, a PhD student. Real honour working with such talents!
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ule_lab@ule_lab·
@KlaraKuret @biorxivpreprint This is the first manuscript fully done by the Ljubljana satellite of the RNA networks lab! Originated by Aram @amalietti, an incredible software developer who wrote the code, and then taken over by Klara, a PhD student. Real honour working with such talents!
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ule_lab@ule_lab·
@SinaRafiee_bio Congrats Sina! Very valuable findings and new methods SPACE and SPACEmap to isolate chromatin components and identify the chromatin-contact regions with high sensitivity.
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Sina Rafiee
Sina Rafiee@SinaRafiee_bio·
Chromatin-contact atlas reveals disorder-mediated protein interactions and moonlighting chromatin-associated RBPs academic.oup.com/nar/advance-ar…
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Paulo Gameiro
Paulo Gameiro@PauloGameiro8·
@ule_lab jbc.org/article/S0021-… Latest, a 13C-based assay to quantify the turnover of base modifications in newly transcribed RNA, by mass spectrometry. We uncover the origin of RNA modifications in digested RNA, and assess their sensitivity to metabolic stresses.
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