
Superveg
1.1K posts




Okay so in case you’re wondering how many cases we’ll see in $abvx Pt2 see table below. Expect about 1-4 total cancer cases in the 50mg arm and 0-2 total cancer cases in the 25mg arm. That will be normal. In line with the IBD baseline* below. So don’t panic when you see that. The pbo derived pts in the 50mg arm will also be a key sub group to follow. A 0 to 1 non NMSC disclosure in this subgroup empirically refutes the drug causation hypothesis Also in Pt1 the guys made a very good point pbo arm structurally undercounts background cancers (due to completion %) Any analysis that uses the pbo arm raw event count as the comparator without exposure time correction will systematically overstate any apparent signal in the active treatment arms. Still can’t believe we’re having this debate. But happy to make sure everyone is informed. *Derived from propensity matched real world dataset (162 events in 5,089 IBD pts over 4 years = 0.796 per 100 PY)

سعودي سعوووددي مسوي لعبه وهذا تصميم البطلة 😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭🙏🙏🙏🙏🙏🙏🧎♀️🧎♀️🧎♀️🧎♀️🧎♀️🧎♀️🧎♀️فاينللي مافيه ناقه مافيه صحراء مافيه بيت شعر 😭😭😭😭😭




We are banning social media access for under 16s. These days kids must find their feet in a world where technology intrudes into every area of their life. I just can’t let that go on anymore. So we’re giving children their childhoods back.



No.431、人物ペン入れ完了。


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No.431、人物ペン入れ完了。



النوادي المدرسية أكثر شيء كنت نتمنى أنه موجود عندنا

















