Carter Lab

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Carter Lab

Carter Lab

@Carter_Lab

Sumali Ağustos 2015
522 Sinusundan3.8K Mga Tagasunod
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Carter Lab
Carter Lab@Carter_Lab·
Check out this stunning animation by @janetiwasa (in collaboration with @SamReckPeterson), showcasing our model of how various components come together to form active dynein complexes capable of transporting cellular cargo.
Carter Lab@Carter_Lab

Our work on how the lysosomal adaptor JIP3, and regulator LIS1 activate the dynein motor protein is now out in @ScienceMagazine ! science.org/doi/10.1126/sc… Many thanks to our reviewers and editor for their valuable input.

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Carter Lab
Carter Lab@Carter_Lab·
Excited to share our latest work with the bullock lab! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before. biorxiv.org/content/10.110…
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Vanessa Teixeira
Vanessa Teixeira@teix_vanessa·
My PhD work is finally out in @JCellBiol! 🎉 Reach out if you want to know more 😉
Journal of Cell Biology@JCellBiol

Teixeira et al @i3S_UPorto identify the onconeural antigen CDR2 as ER-localized adaptor for the microtubule-based motor cytoplasmic dynein-1 & show that CDR2 contributes to ER organization thru. its interaction w/ the integral ER membrane protein kinectin hubs.la/Q03wGLyX0

Póvoa de Varzim, Portugal 🇵🇹 English
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Carter Lab
Carter Lab@Carter_Lab·
A one day meeting on Friday 6th December covering all aspects (and scales) of Structural Biology.  Lots of talk slots to be selected from abstracts.  Deadline for abstracts is this Friday (15th Nov). bit.ly/4fDEqfZ
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Sam Lacey
Sam Lacey@samlacey745·
Our paper looking at the structure of retrograde IFT trains is out now! Have a look at the link, or see some of the headlines in this video: cell.com/cell/fulltext/…
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Carter Lab
Carter Lab@Carter_Lab·
My first PhD student, Emma Hanford (nee Gleave), made some cysteine-lite dynein constructs in 2013. 11 years later, thanks to MinFlux, Joseph Slivka and @Yildiz_Lab they have been used in a nice biorxiv paper. doi.org/10.1101/2024.0…
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Carter Lab
Carter Lab@Carter_Lab·
Today in Journal Club - Cross-link assisted spatial proteomics to map sub-organelle proteomes and membrane protein topologies nature.com/articles/s4146…
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Diorge Souza
Diorge Souza@diorge_souza·
We're thrilled to share our new preprint: "Evolutionarily Conserved Principles of ESCRT-III-Mediated Membrane Remodeling Revealed by a Two-Subunit Asgard Archaeal System." biorxiv.org/content/10.110…
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Ina Harasimov
Ina Harasimov@i_harasimov·
Excited to share our latest study! We discovered that maintaining mammalian oocytes involves extraordinary protein longevity. These proteins support key functions like proteostasis, the cytoskeleton, and mitochondria. Our findings offer new insights into reproductive aging.
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Schuh Lab@SchuhLab

Women are born with all their oocytes, which need to stay viable for decades to ensure fertility. How are they maintained for that long? Our latest research in @NatureCellBio reveals that oocyte maintenance involves exceptional protein longevity. nature.com/articles/s4155… (1/9)

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Carter Lab
Carter Lab@Carter_Lab·
In yesterday's #journalclub, we had a look at the interesting mechanism by which the UNC-104 motor (Kinesin-3 KIF1A homologue in C. elegans) is stabilised on Rab-3-containing synaptic vesicles - by Bhan and colleagues biorxiv.org/content/10.110…
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Carter Lab
Carter Lab@Carter_Lab·
Today in #journalclub we delved into the structure of the Flotillin complex. Fascinating insights into how this cage complex could induce membrane curvature and provide a sealed diffusion barrier, connecting membrane systems. biorxiv.org/content/10.110…
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Tuklasin

@teix_vanessa @JCellBiol @NicolaJGI @Yildiz_Lab @ScienceMagazine @elonmusk @BarackObama @taylorswift13