The Naef Lab

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The Naef Lab

The Naef Lab

@NaefLab

Lab of computational and systems biology @EPFL_en. Interested in #circadian rhythm, #GeneRegulation, oscillators, single cells, transcription, theory, and more!

Lausanne, Switzerland Sumali Kasım 2013
103 Sinusundan771 Mga Tagasunod
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Cédric Gobet
Cédric Gobet@TebogCirdec·
🚨 Two new preprints on BioRxiv! 🚨 We’re excited to share two complementary studies built on a shared dataset, exploring how cells regulate translation elongation under amino acid starvation, from computational and biological angles. 🧠 + 🧬 = 🔬💥 Read on 👇
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The Naef Lab
The Naef Lab@NaefLab·
Individuals with low hepatic VLDLR mRNA levels exhibit lipid deposition in the coronary artery and an increased incidence of heart attack. This breakthrough could have major implications for cardiovascular disease research. Read more: nature.com/articles/s4146…
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The Naef Lab
The Naef Lab@NaefLab·
Thrilled to share that our latest research, led by @TomazMartini, has been published in Nature Communications! We discovered that VLDLR is highly expressed around hepatic central veins, particularly in female mice and premenopausal women compared to similarly aged males.
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EMBL Events
EMBL Events@EMBLEvents·
✨ We are proud to announce the winners of the best poster prizes at the recent EMBO | EMBL Symposium 'Biological oscillators' 🙌 A round of applause goes to: 🏅 Yasmine el Azhar, Hubrecht Institute, The Netherlands 🏅 Dinesh Jadhav, Department of Biology, Ashoka University, India 🏅 Julian Pietsch, Max Planck Institute for Terrestrial Microbiology, Germany 🏅 Elena Tonin, EPFL, Switzerland Take a moment to explore their outstanding contributions ➡️ s.embl.org/posterprizeEES… #EESBioOsc
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The Naef Lab
The Naef Lab@NaefLab·
🕰️ The 'Towards clinically actionable molecular biomarkers of the circadian clock' symposium in Venice has just kicked off. Looking forward to insightful discussions ahead! #CircadianResearch #WarwickInVenice
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The Naef Lab
The Naef Lab@NaefLab·
Together, our work provides new insights into the sexual dimorphism characterizing differences in VLDL kinetics and atherosclerotic cardiovascular disease. (5/5)
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The Naef Lab
The Naef Lab@NaefLab·
In humans, low hepatic #VLDLR expression correlates with a medical history of heart attack, and with atherosclerosis severity. (4/5)
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The Naef Lab
The Naef Lab@NaefLab·
Of interest to us: #syntheticbiology, #systemsbiology, #compbio, #cellular and #tissue engineering, #biomaterials, #functionalgenomics, #proteomics and #metabolomics. Encouraged topics: #cancerbiology, #infection, #immunology, #metabolism, #neuroscience, #neurorehabilitation.
The Naef Lab@NaefLab

Looking for a Tenure-track Professor position at @EPFL_en? Great opportunity, totally open topic in Life Science Engineering! epfl.ch/about/working/… Still one month to go: screening will start on Dec 15.

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The Naef Lab
The Naef Lab@NaefLab·
Congrats Nick & Tinh-Hai for very nice work! Happy it's out. Pretty impressive the Bayesian model that you implemented! I like the exact treatment of the continuous vs discrete ODE model (not so trivial...) Should be very useful for many case studies.
Nick Phillips@NPSysBio

Very happy that our article "Uncovering personalized glucose responses and circadian rhythms from multiple wearable biosensors with Bayesian dynamical modeling" is now online in Cell Reports Methods! (doi.org/10.1016/j.crme…) A brief overview... (1/5)

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The Naef Lab
The Naef Lab@NaefLab·
Excellent new paper by the @Fitzgerald__lab on sexual dimorphism in chronobiology, which is getting more and more interesting!
Society for Research on Biological Rhythms@SRBR_Outreach

What happens to your body under circadian stress, eg shift work, and does everyone suffer the same? @Fitzgerald__lab show that females are more resilient than males at behavioural and molecular levels, which may involve interactions with the microbiome: science.org/doi/10.1126/sc…

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Tuklasin

@GioeleLaManno @TomazMartini @molina_lab @epflSV @cziscience @EPFL_en @FEBS_Letters @elena_tonin