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Selectome
90 posts
Selectome
@Selectome
Selectome is a database of positive selection based on a rigorous branch-site specific likelihood test
Lausanne Sumali Temmuz 2012
15 Sinusundan102 Mga Tagasunod
Well that was fast, we're back up. 👍
Selectome@Selectome
Due to necessary maintenance on our servers, Selectome is down for a few hours. Thank you for your patience.
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Finally, after all these years, a paper describing all the data, #biocuration and tools in the Bgee database of gene expression!
Read, enjoy, and give us feedback (and cite). @fred_bstn et al 😀
biorxiv.org/content/10.110… #rnaseq #bioinformatics #database
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Interested in applying your bioinformatics skills to cancer research? Consider joining my lab @unil Lausanne as a post-doc. Details + contact in the attached document.
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Hello world! After some time of dormancy, we are back in business!
First, new interface and new url:
selectome.org
New selection data based on recent @ensembl gene trees and Godon software coming soon! @idavydov @seb_moretti @marc_rr @nicsalamin @DEE_UNIL
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Ensembl 99 and @ensemblgenomes 46 are scheduled for December 2019. We've got a bumper set of new #reptiles 🐍, #fish 🐠, #mammals 🦇🐋, #birds 🦅 , #plants 🌱 and #metazoa 🐌! Read the full list of intentions on our blog:
buff.ly/33Bwztf
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In their study, @fannypouyet et al. found that 95% of our genome seems to be affected by background selection and other genetic biases - here biaised gene conversion: goo.gl/48pnzG | thanks @DanGraur for pointing this out
SIB@ISBSIB
A study @eLife by @fannypouyet et al. at SIB's @loronet gp @unibern shows that 95% of our #genome is affected by some kind of selection, and that markers considered as neutral & used as 'standards' for #demographic studies can lead to biased estimates: goo.gl/48pnzG
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After reading doi.org/10.1101/174839 (with @marc_rr & @nicsalamin) @DavidEnard suggested that extensive positive selection on background branches could decrease power of the branch-site test and our new method, especially in Drosophila. 1/7
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In particular, two PhD positions with @marc_rr and @nicsalamin at UNIL/SIB on Big Data comparative genomics (sorry!) lab.dessimoz.org/phd-bigdata
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#biocuration ift.tt/1rC4crr dbDSM: a manually curated database for deleterious synonymous mutations.
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New realistic method for detecting positive selection (dN/dS). Want to learn more? Tweet me, poster 21. #biology16
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Selectome data inside: distinguishing dN/dS components of purifying selection, neutral evolution, positive selection twitter.com/marc_rr/status…
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Retweeting with production instead of development URL: selectome.unil.ch/cgi-bin/subfam… twitter.com/Selectome/stat…
Selectome@Selectome
CFCF, #Geneoftheweek of @ensembl (and @EncodeDCC favorite), evolved under positive selection: altselectome.unil.ch/cgi-bin/subfam… twitter.com/ensembl/status…
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