Vasudevan Lab

Delighted to host the first annual @VasuLabUCSF holiday party - grateful to work with these people every day.

Exciting new paper by @VasuLabUCSF et al! "IFN signaling is associated with radiotherapy response in malignant peripheral nerve sheath tumors" jci.org/articles/view/… @NeurosurgUCSF @UCSFHospitals

This study is directly relevant to the clinical care of patients with the most common malignant tumor of the peripheral nervous system, while providing fundamental biological insight👇 Harish N. Vasudevan @VasuLabUCSF & team @UCSF reveal transcriptional, functional genetic, and cellular mechanisms of interferon signaling that underlie radiotherapy response in people with #MPNST: doi.org/10.1172/JCI195…

NF1 is frequently mutated in #glioblastoma, yet therapies targeting this alteration often fall short. @VasuLabUCSF & team @UCSF now show NF1 mutant glioblastomas exhibit prognostic signatures with distinct sensitivity to MEK inhibition: insight.jci.org/articles/view/…

Excellent time giving grand rounds last week @UMRogelCancer with old friends @gouthamnarla and new ones @castro2355_mg @UCSFCancer @NeurosurgUCSF

Happy 4th of July - to celebrate, we asked if there is meaningful heterogeneity within somatic NF1 mutant glioblastomas? We think so biorxiv.org/content/10.110… As always, appreciate everyone that made this work possible @NeurosurgUCSF @UCSFCancer @ntapresearch @ChildrensTumor

A delightful time catching up with 10 of NTAP’s 18 Francis S. Collins Scholars & their mentors while in Brussels @ChildrensTumor. Thank you all for your dedication to moving the needle in NF1 research! #NFCON24 #endNF

Sunrise-ish run through brussels - enjoying every part of the annual @ChildrensTumor meeting #nfcon24 with friends from @NeurosurgUCSF @ntapresearch

Excited that our DoD New Investigator Award (cdmrp.health.mil/nfrp/awards/23…) is officially funded - thanks to everyone that helped make this happen @CDMRP @domespo @simanshu and time to get to work!

A pleasure to review the therapeutic landscape for NF-1 with my future colleague @bnamd87 rdcu.be/dG8Lq

Additionally, in a study led by @VasuLabUCSF & @LabRaleigh, researchers demonstrate how NF-1 mutant Schwann cell tumors undergo malignant transformation, identifying new potential strategies against treatment resistance: nature.com/articles/s4146… @UCSFCancer #neurofibromatosis

New featured image on our homepage! nature.com/ncomms/ 3 papers on schwannomas, tumors of the nervous system derived from Schwann cells @VasuLabUCSF @LabRaleigh @sjohnliu #CancerResearch @NatResCancer nature.com/articles/s4146… nature.com/articles/s4146… nature.com/articles/s4146…

Very proud of @LexiHaugh for her analysis of targeted DNA sequencing in cutaneous melanoma: biorxiv.org/content/10.110… @ad1600

Delighted to share that our work looking at functional interactions between neurofibromatosis tumor suppressors is officially accepted: rdcu.be/dvPyh

Looking forward to #SNO2023 presentation by #FrancisSCollinsScholar @VasuLabUCSF presenting innovative approaches to targeting NF1 loss in nervous system tumors @NeuroOnc @NTAPresearch @HopkinsMedicine #NF

Our manuscript investigating bulk and single cell genomics of melanoma brain metastases is now online! Many thanks to everyone that made this work possible jamanetwork.com/journals/jaman…

So pleased to see our work in @NatureComms, led by @SkakodubAnna, @hswalch, and @KathrynTringale, with @nikolausschultz, describing the genomics and clinical outcomes of a large set of patients with NSCLC brain metastasis. @MSKCancerCenter @MSK_RadOnc rdcu.be/djJ2f

Big congratulations to @LexiHaugh on her ASCO YIA! Excited to make some progress on (NF1 mutant) metastatic melanoma

The Vasudevan Lab makes its first twitter post: Excited to share our preprint looking at functional interactions between NF tumor suppressors assets.researchsquare.com/files/rs-19337…