Lorenzo Cingolani

Watching neurons fire at synaptic resolution Example of the activity we study 👇

🧠 Can we reprogram dysfunctional neural circuits? 📢 PhD position in synaptic magnetogenetics (@UniTrieste) Italy 🧪Patch-clamp, Ca2+ imaging, MEA EIC Pathfinder (SynMech) 📅Deadline: May 17 Apply here👇 fens.org/careers/job-ma… #PhDPosition #Neuroscience #Electrophysiology

Online now: Infant learning forms lasting memory schemas that influence adult behavior dlvr.it/TRz4PL

Master these cognitive biases before they master you.

The patterns of trigonometry.

Astroengrams: rethinking the cellular substrate for memory — a Perspective by Javier Sánchez Romero & Marta Navarrete nature.com/articles/s4158…

Online now: Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry dlvr.it/TQ6t8H

How animals detect the Earth’s magnetic field remains a mystery in sensory biology. In a new Science study, researchers used whole brain activity mapping, tissue clearing, and light sheet microscopy to identify neuronal populations activated by magnetic stimuli in the pigeon. Learn more: t.co/DV1MEXigKV

🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them. 🔗 janelia.org/news/researche…

A collaborative study with the group of Ildiko Dunay on "Reduced synaptic tagging by complement protein C3 is associated with elevated extracellular matrix in the middle-aged cerebellum of mice" is available online: frontiersin.org/articles/10.33…

We found that vCA1 neurons encode social memories across multiple representational dimensions, using distinct neural populations to represent individual identity and social properties such as sex.

A common computational and neural anomaly across mouse models of autism "Mice harboring mutations in Fmr1, Cntnap2 or Shank3B show a blunted update of priors during decision-making." nature.com/articles/s4159…

There are two possible outcomes: if the result confirms the hypothesis, then you've made a measurement. If the result is contrary to the hypothesis, then you've made a discovery. - Enrico Fermi

New findings reveal a #posttranscriptional mechanism that is critically involved in a process called homeostatic scaling, which adjusts the activity of chronically underactive or overactive #neurons that would otherwise impair brain function. @SciSignal scim.ag/3S5dJGn

Prefrontal ErbB4-positive interneurons for avoidance: Cell Reports Pleasant read. Classical experimental layout. RNA-Seq > cell Identity > up/down cell manipulation > circuit manipulation > behavioral assessment > rescue cell.com/cell-reports/f…

❗️❗️❗️News︱Nature neuroscience 👏👏👏Prof. Yingjie Zhu's team uncovered the neural circuit mechanism by which social factors regulate addiction susceptibility. 👇More nature.com/articles/s4159…

This looks great!

Online now: Presynaptic α2δs specify synaptic gain, not synaptogenesis, in the mammalian brain dlvr.it/TKlBwt

Social rank modulates methamphetamine-seeking in dominant and subordinate male rodents via distinct #dopamine pathways nature.com/articles/s4159…

The Handbook of Ephys is out!! doi.org/10.1142/14331 "How to Patch a Cell"- a quick-start guide for people who are fresh to whole-cell patching. "Multiple Whole-Cell Recordings"- goes into details of obtaining quality recordings of dual- to 4-cell patch. Enjoy!😃