@ErinGillaspie @VUMChealth @WomenInThoracic @womeninsurgery @WomenSurgeons Congratulations! Best of luck!
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Darren Bryan
529 posts
Darren Bryan
@DSBryan1
Thoracic surgeon at the University of Chicago @UChicagoCTSurg. @BrighamThoracic @uchicagosurgery @MacLeanEthics alum. Husband of/inspired by: @avafbryan
City of the Big Shoulders شامل ہوئے Mayıs 2012
478 فالونگ524 فالوورز
Signed out the Gillaspie service one last time…After 7 1/2 extraordinary years @VUMChealth I am off on my next adventure as the Chief of Thoracic Surgery at #CreightonUniversityMedicalCenter …so excited for this new chapter!! @WomenInThoracic @womeninsurgery @WomenSurgeons
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@JackWestMD @BrendonStilesMD Big fan the term “aspirationally resectable”
And, agree. Need to focus on meeting current standards for high quality lung cancer surgery. But as a field, we should still have certain people pushing the boundaries. Doing so shouldn’t distract from high quality surgery, everywhere
Chicago, IL 🇺🇸 English
@BrendonStilesMD I'm not saying that you or the Altorkis, Spicers, & Swishers of the world can't use your good judgment to say 3B MAY be resectable, but saying we should routinize broadening to "aspirationally resectable" for surgeons who do CCY same day as occasional lung surgery is a BAD idea.
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Almost all tumors are technically resectable - the question is “should we resect?”
Perhaps more so than converting tumors, we need to convert physicians with an “unresectable” first mentality to a “resectable” mentality. #lcsm #TexasLung23
TLC Conference@TLCconference
Are you joining us this month for The Texas Lung Cancer Conference? We don't want you to miss thought leader @BrendonStilesMD presentation on "Can We Convert Unresectable To Resectable?". Full agenda here: hubs.la/Q01FV-v70 #TexasLung23 @medical_cons
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Darren Bryan ری ٹویٹ کیا
Aren’t You the Valet? Tales of Black American Surgeons | NEJM Today, in the US, it is as if there are 2 different scripts being loudly declaimed trying to drown each other out. The escalating chant “BLM” is countered by … cancel culture & White supremacy. nejm.org/doi/full/10.10…
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5 year follow up from a 2018 phase-II pilot study of neoadj. nivolumab (nejm.org/doi/full/10.10…). Impressive outcomes!
aacr.org/about-the-aacr…
Patrick Forde@FordePatrick
And here is a graphic of the five year outcomes!
Chicago, IL 🇺🇸 English
Darren Bryan ری ٹویٹ کیا
Thank you for sharing your experience!
Hearing my patients’ stories over the years during surveillance has led me to believe (even though i cannot prove) that PFTs have value in risk-stratification, but they do not predict patient experience.
Jill Feldman@jillfeldman4
@FarhoodFarjah YES! My PFT's were fine post lobectomy but I was easily SOB when playing sports w/my 4 kids. AND there's only a finite amount of lung - I lived that horror/reality w/my aunt, whose 3rd stage I killed her because she didn’t have enough lung capacity to survive another surgery!
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@FarhoodFarjah @ElliotServaisMD @ekslim @JVelottaMD @DrYolondaColson @DoctorJSpicer @DouglasEWood1 @EADavidMD @ErinGillaspie @ewakeam @girlceppa @hari_keshava @Howington8John @IanCBostock1 @jdoningtonmd @jdphillipsMD @rjmehran @JulesLin99 @katberfieldMD Also curious about this. In fellowship our pathologists would regularly and it would help guide decision making. Particularly with STAS (though recognizing the difficulty to call it on a frozen specimen)
Chicago, IL 🇺🇸 English
@ElliotServaisMD @ekslim @JVelottaMD @DrYolondaColson @DSBryan1 @DoctorJSpicer @DouglasEWood1 @EADavidMD @ErinGillaspie @ewakeam @girlceppa @hari_keshava @Howington8John @IanCBostock1 @jdoningtonmd @jdphillipsMD @rjmehran @JulesLin99 @katberfieldMD are folks getting pathologists to look for as many path features as possible on wedge to help guide these decisions?
if not, then surgeons would not have a basis for selecting extent based on path parameters.
if so, what specific features are you asking for routinely intraop?
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. @DrYolondaColson @DSBryan1 @DoctorJSpicer @DouglasEWood1 @EADavidMD @edwardyhchang @ekslim @ElliotServaisMD @ErinGillaspie @ewakeam @girlceppa @hari_keshava @Howington8John @IanCBostock1 @jdoningtonmd @jdphillipsMD @rjmehran @JulesLin99 @JVelottaMD @katberfieldMD
Farhood Farjah@FarhoodFarjah
What would you recommend? -average risk patient fit for lobectomy -peripheral cT1N0M0 NSCLC -RUL -1.7cm -solid (no prior imaging) -SUV 4 -wedge would -> (-) margins -single segment would -> (-) margins -patient preference to optimize efficacy/safety/HRQOL
QAM
Darren Bryan ری ٹویٹ کیا
Delighted to announce MARS 2 data is now mature and we aim to report this year! Thank you to our patients, UK investigators, @BrsTrialsCentre, @NIHRresearch @CRUKresearch for 7 years of hard work!!
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Farhood Farjah@FarhoodFarjah
@SethBKrantz @DSBryan1 @ElliotServaisMD @DavidCookeMD @TomVargheseJr @DrShawnGroth @BrendonStilesMD @ShandaBlackmon @LindaMThoracic Agree with a disease-based rather than procedure-based approach to knowledge acquisition for the subspecialist surgeon practicing non-cardiac thoracic surgery.
Chicago, IL 🇺🇸 English
@ElliotServaisMD @DavidCookeMD @TomVargheseJr @DrShawnGroth @BrendonStilesMD @ShandaBlackmon @LindaMThoracic Fascinating time to be in this field!
5 all time:
Z0030
CROSS
NLST
PACIFIC
CM816
5 in the last 5 years (interested to see how others place these in the all-time list)
CM 816
CM 577
ADAURA
Impower010
NADIM
Chicago, IL 🇺🇸 English
Been a while since I surveyed this…
There have been many game-changing studies in the last few years.
What are the 5 most impactful studies all general thoracic trainees should know?
@DavidCookeMD @TomVargheseJr @DrShawnGroth @BrendonStilesMD @ShandaBlackmon @LindaMThoracic
Elliot Servais, MD, FACS@ElliotServaisMD
General thoracic surgeons: What are the 5 most impactful studies in the last 20 years that all residents/fellows/surgeons should know? Here's a start: -CALGB 39802 -INT 0139 -ACOSOG Z0030 -CROSS trial -NLST #tssmn @STS_CTsurgery @AATSHQ @TSRA_official #CTSurgery @TOutcomes
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Darren Bryan ری ٹویٹ کیا
AUDARA update with longer F/U but OS data still withheld ascopubs.org/doi/pdf/10.120…
Interesting👀 Brain mets incidence starts to rise AFTER 3 years osi is up in stage II/IIIA while in control group it plateaus at ~10%. So does osi really only delay recurrence?🧐
Do we need MRIs???
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Darren Bryan ری ٹویٹ کیا
Importantly, for clinical relevance, we show that we can predict recurrence after surgery in a cohort of Stage 1A-B lung cancer patients by using machine learning and as a result can inform on adjuvant treatment strategies. We don’t need 35 markers- we can do this with just 6! 🙌🏼
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Lack of viewpoint diversity in academia is a palpable problem. The moral+intellectual decline of the GOP+American conservatism are also palpable problems. These are mutually reinforcing challenges.
Keith Humphreys@KeithNHumphreys
I am surprised that departments of religion have a 70:1 ratio of Democrats to Republicans on their faculties.
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Darren Bryan ری ٹویٹ کیا
Dr John Alverdy’s last day in the OR after 30 years at @uchicagosurgery Thousands of patients have benefited from his expertise, and his legacy includes hundreds of trainees - THE BEST. #ThankYou @UChicagoMed #EndOfAnEra #TheLegend #NewChapter #HesNotGoingAnywhere
Chicago, IL 🇺🇸 English
Darren Bryan ری ٹویٹ کیا
@esinghimd @ADesaiMD @FDAOncology @DrSteveMartin @n8pennell @JackWestMD Here’s some help: just do neoadj and you’ll hardly ever have to think about this adj business. The real question is whether there’s value in adj IO for patients who received neoadj chemo-IO. That’s the real question for which we will soon have some useful data. #LCSM
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Darren Bryan ری ٹویٹ کیا
I am incredibly appreciative to be at an institution that values diversity and equity. I am proud of the work we do to combat structural racism and improve access to care. @UChicagosurgery promotes a positive and inclusive environment
Jeff Matthews MD@JBMatthews
Learn about our extraordinary Chief of Thoracic Surgery Dr Jessica Donington and who she is “behind the mask”. @jdoningtonmd @uchicagosurgery surgeryar.bsd.uchicago.edu/sections/thora…
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In a mildly related note, Starbucks espresso is gross right? Why is no one talking about this
South Carolina, USA 🇺🇸 English
Nothing makes me revert to college habits like a grant deadline. No sleep, absolute junk food, wearing pjs (scrubs) to work…
GIF
South Carolina, USA 🇺🇸 English
Darren Bryan ری ٹویٹ کیا
Issue Information ‐ TOC onlinelibrary.wiley.com/doi/10.1002/js…
This month's issue of JSO puts the spotlight on thoracic oncology and our own Dr. Mike Jacklitsch @BrighamSurgery @BrighamThoracic
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@DrRianCharles @jdphillipsMD @TOutcomes @STS_CTsurgery @DartSurgery @DartmouthCancer @DartmouthHealth Important topic! Couldn’t be there this year but looking forward to seeing the manuscript
Chicago, IL 🇺🇸 English
Excellent job by @jdphillipsMD describing the collaborative @TOutcomes study looking at the impact of living in a food desert and esophageal cancer tx experiences. Another way to improve patient outcomes! @STS_CTsurgery @DartSurgery @DartmouthCancer @DartmouthHealth #STS2023
San Diego, CA 🇺🇸 English