Rake

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Rake

@GoForRake

Virtual Bodyguard. Human enhancement + longevity enthusiast.

شامل ہوئے Mart 2018
560 فالونگ173 فالوورز
Benjamin Cowen
Benjamin Cowen@intocryptoverse·
@cryptivaaa What did 2013, 2017, 2021 and 2025 all have in common? BTC topped in Q4 of each of those years before a bear market. There is a narrative for everything, but narratives follow price.
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Benjamin Cowen
Benjamin Cowen@intocryptoverse·
If Bitcoin continues to follow 2014, then the next leg down could be sooner than most expect. Usually there is weakness by Bitcoin going into April of midterm years.
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Rake
Rake@GoForRake·
It's a fantastic model, been coding with it for the past few days. It's both smart and fast.
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Aakash Gupta
Aakash Gupta@aakashgupta·
The entire AI industry spent a week convinced DeepSeek had secretly launched V4. Reuters reported it. Developers debated it. OpenRouter usage charts broke. It was Xiaomi. A smartphone and electric vehicle company just shipped a 1-trillion-parameter model that topped the world's largest API aggregation platform, and nobody guessed the origin because the model was too good to be associated with a hardware company. The stealth launch as "Hunter Alpha" on March 11 was the most elegant product validation in recent AI history. No brand, no attribution, no expectations. Just raw performance. The model processed over 1 trillion tokens in 8 days. Developers organically chose it over every labeled frontier model on the platform. When Reuters tested the chatbot, it identified itself only as "a Chinese AI model primarily trained in Chinese" with a May 2025 knowledge cutoff, the exact same cutoff DeepSeek reports. The person behind this is Luo Fuli. Born in 1995. Eight papers at ACL as a graduate student at Peking University. Alibaba DAMO Academy. Then DeepSeek, where she co-developed V2 and contributed to R1. Lei Jun reportedly offered tens of millions of yuan to recruit her. She joined Xiaomi in November 2025. Four months later, she's shipping a model that benchmarks alongside Claude Sonnet 4.6 and GPT-5.2 at one-fifth the API cost. The detail that tells you everything about how this team operates: when Luo first experienced a complex agentic scaffold, she tried to convince the MiMo team to adopt it. They resisted. So she issued a mandate. Anyone on the team with fewer than 100 conversations with the system by tomorrow can quit. They all stayed. The imagination converted into research velocity. The architectural bets matter. Hybrid Attention for long-context efficiency. MTP inference for low latency. 1M context window. 42B activated parameters out of 1T total. These are infrastructure decisions optimized for agents that run autonomously for hours, not chatbots that answer one question at a time. Pricing: $1/$3 per million tokens up to 256K context. $2/$6 for 256K to 1M. Claude Sonnet 4.6 costs roughly 5x that. Xiaomi's shares rose 5.8% on the announcement. The real DeepSeek V4 still hasn't shipped. The model everyone mistook for it already has a trillion tokens of real-world usage data.
Fuli Luo@_LuoFuli

MiMo-V2-Pro & Omni & TTS is out. Our first full-stack model family built truly for the Agent era. I call this a quiet ambush — not because we planned it, but because the shift from Chat to Agent paradigm happened so fast, even we barely believed it. Somewhere in between was a process that was thrilling, painful, and fascinating all at once. The 1T base model started training months ago. The original goal was long-context reasoning efficiency. Hybrid Attention carries real innovation, without overreaching — and it turns out to be exactly the right foundation for the Agent era. 1M context window. MTP inference for ultra-low latency and cost. These architectural decisions weren't trendy. They were a structural advantage we built before we needed it. What changed everything was experiencing a complex agentic scaffold — what I'd call orchestrated Context — for the first time. I was shocked on day one. I tried to convince the team to use it. That didn't work. So I gave a hard mandate: anyone on MiMo Team with fewer than 100 conversations tomorrow can quit. It worked. Once the team's imagination was ignited by what agentic systems could do, that imagination converted directly into research velocity. People ask why we move so fast. I saw it firsthand building DeepSeek R1. My honest summary: — Backbone and Infra research has long cycles. You need strategic conviction a year before it pays off. — Posttrain agility is a different muscle: product intuition driving evaluation, iteration cycles compressed, paradigm shifts caught early. — And the constant: curiosity, sharp technical instinct, decisive execution, full commitment — and something that's easy to underestimate: a genuine love for the world you're building for. We will open-source — when the models are stable enough to deserve it. From Beijing, very late, not quite awake.

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Rake
Rake@GoForRake·
@ZssBecker Red light panels were one of those things that I figured would be a complete scam, but are actually fantastic. My skin tone improved dramatically, almost no adult acne anymore (hated that) and improved HRV.
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Alex Becker 🍊🏆🥇
Finally achieved the holy trinity of longevity. Home Gym. In home dry sauna. In home Hyperbaric chamber. Red light therapy. 5-6x a week. I'm living to 300 or going to die trying.
Alex Becker 🍊🏆🥇 tweet mediaAlex Becker 🍊🏆🥇 tweet mediaAlex Becker 🍊🏆🥇 tweet mediaAlex Becker 🍊🏆🥇 tweet media
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Rake
Rake@GoForRake·
Taking psyllium husk mixed with potato starch gives me the most unhinged dreams. I suspect it's from an increase in butyrate production. Next morning is like shitting a brick, though.
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Rake ری ٹویٹ کیا
Bryan Johnson
Bryan Johnson@bryan_johnson·
Two doses of magic mushrooms degraded my sperm count from the 99.6th percentile to the 77.7th. This may be a first-in-human observation. Context: we ran the most quantified magic mushroom (psilocybin) experiment ever conducted. We were asking if psilocybin is a longevity therapy. After seeing the data, we think it is (see reply post for the experiment summary). Also, like most things biology: the results are complicated. My data suggests that the magic mushrooms (psilocybin) negatively impacted my fertility markers. Before the first psilocybin dose my motile sperm count was at 99.6th percentile for men under 25 years of age, it dropped to 77.7% and partially recovered to 89.3% following the first dose, and second doses, compared to the same age cohort (numbers compare similarly to my age cohort as well). 3 days following my second dose (first dose 25 mg, second dose 28 mg) . Motility: dropped 51% . Total count: almost unchanged, dropped by 2% . Total motile count: dropped 52% . Normal morphology: dropped by 50% 20 days post 2nd dose, the pattern continued, with typical latent effects on total sperm counts Motility: recovered back to -2% of pre-psilocybin baseline: . Total count: dropped by 38%, latent effect. . Total motile count: remained inhibited at -39% of pre-psilocybin baseline, (despite motility normalizing, due to the total count drop) . Morphology normalized to -10% of baseline levels. Reduction in free testosterone might have contributed to the effect. While total serum testosterone increased by 30% 3 days following the 2nd dose (neither FSH or LH were meaningfully affected either), and continued to be at 11% above baseline, SHBG increased by 37%, SHBG binds testosterone and reduces its bioavailability and activity. My free testosterone (direct) showed 24% and 23% drops at 3 and 20 days post 2nd dose. In light of the neuroplastic, well-being, brain reset, and systemic metabolic and anti-inflammatory benefits, the trade-off is probably worth it. Especially considering that the magnitude of inhibition has no meaningful effect on actual fertility (total motile counts above 50 million are still on the safe side). This is a first-in-human observation, to our knowledge there is no published human clinical study demonstrating that psilocybin diminishes male fertility markers. General mechanistic evidence exists for recreational and psychoactive drugs possibly inhibiting fertility markers due to their effects on the hypothalamus-pituitary-adrenal axis and general hormonal reset.  Yet no direct evidence for psilocybin or other similar psychedelics inhibiting fertility markers exist. A potential mechanism for the immediate inhibition of motility could involve direct serotonergic signaling in sperm. Human sperm express multiple serotonin receptors, including 5-HT2A, and one recent study found that a 5-HT2A antagonist reduced sperm motility, suggesting that 5-HT2A may regulate motility. Psilocybin is known to bind 5-HT2A with high affinity.
Bryan Johnson tweet mediaBryan Johnson tweet media
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Rake
Rake@GoForRake·
@DrSamuelBHume Hmm, wonder if Epitalon would be valuable in this context.
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Samuel Hume
Samuel Hume@DrSamuelBHume·
The thymus shrinks as we get older, so is it actually doing anything useful? This study (nature.com/articles/s4158…) measured thymic health based on CT scans, and found: 1. Better thymic health is associated with longer survival
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Rake
Rake@GoForRake·
@hridoyreh GSC data has been extremely odd/delayed for me. Most recent data I have on my account is from March 14th.
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Hridoy Rehman
Hridoy Rehman@hridoyreh·
Guys, this is really very painful. This is data from one of my websites. When I checked the Search Console 7 days ago, there were still 1,500+ pages indexed. But when I checked today, I saw that many pages were no longer indexed. I don't know why this happened. However, I am investigating...
Hridoy Rehman tweet media
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Rake
Rake@GoForRake·
@sethprattsf @SterlingCooley Interestingly, it elevated my heart rate. I did it again before bed, and wouldn't do that again. Made it more difficult to fall asleep. I'll stick to hitting this spot in the morning.
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Sterling Cooley
Sterling Cooley@SterlingCooley·
This research is actually more important that I initially realized* We may be able to target abdominal regions (no more spleen location - which is difficult) if this research holds up and expands further, I don't see why it wouldn't scale up, this could be massive for US-1000 and US-2000 Pro owners, you guys are so darn lucky ! Recent research confirms that transcutaneous focused ultrasound applied to the epigastrium suppresses systemic inflammation by modulating subdiaphragmatic vagus nerve fibers. This non-invasive approach utilizes acoustic pressure to stimulate mechanosensitive vagal afferents. In controlled rodent models, a 10-minute application at 1 MHz resulted in a 180% increase in vagal firing. The physiological result is a significant downregulation of pro-inflammatory cytokines. Data shows a 48% reduction in TNF-α and a 42% drop in IL-1β within two hours of stimulation. The mechanism targets the cholinergic anti-inflammatory pathway. By increasing efferent tone, ultrasound signals the spleen to inhibit cytokine release via α7nAChR receptors on macrophages. Human feasibility trials demonstrate a 30% cytokine reduction. This bioelectronic intervention offers a precise, drug-free alternative for managing rheumatoid arthritis, IBD, and sepsis. pubmed.ncbi.nlm.nih.gov/41671184
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Rake ری ٹویٹ کیا
Curiosity
Curiosity@CuriosityonX·
BREAKING🚨: ALL FIVE types of nucleic acid bases, the building blocks of LIFE 'DNA and RNA', have been found in samples collected from asteroid Ryugu
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Rake
Rake@GoForRake·
@elonmusk Are we going to see a newer version of Grok Code at some point?
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Elon Musk
Elon Musk@elonmusk·
By this weekend, xAI will have three Grok Build models in training simultaneously
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Rake
Rake@GoForRake·
@MattDevost Very much reminds me of the focus on games in The Culture series.
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Matt Devost
Matt Devost@MattDevost·
Many years ago when folks were living their lives in Second Life and World of Warcraft, I predicted the emergence of gaming retirement style communities where you get a place to sleep and shower and you would be served meals while you spend the rest of your time living in games. youtube.com/watch?v=9v6LWn…
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Rake
Rake@GoForRake·
@Iammarcmalone You're the only other person I've ever seen mention nobiletin "in the wild". It's a fascinating compound.
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Marc Malone
Marc Malone@Iammarcmalone·
Most disease is not injury/trauma but systemic - and should be handled that way. There is rarely a single silver bullet for any disorder, because disorder like order, is holistic. But some key starting points from my experience: 1. Migraines disappeared with histamine control - antihistamines in acute phase, longer term with histamine, mast cell and inflammatory control via things like Quercetin & Bromelain. 2. Respiratory improvemed significantly with NAC (unlocking innate Glutathione) for inflammatory inhibition and oxidative phosphorylation support + Mullein Oil. 3. Sleep with circadian rhythm support with things like nobelitin for Bmal1/Clock genes transcription, and magnesium for displaced synaptic ions (usually displaced from inflammatory cascades). And Testosterone through giving less of a shit about things that don't matter in the end + cigars, heavy metal, and driving 5 miles over the speed limit.
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Rake
Rake@GoForRake·
@nealasher @GrindItOut They don't want to know, it's exhausting. Generally speaking, people just want to be left alone. If they can afford to go out for chicken tendies and movies once every couple months, they're happy to leave all that thinking to others.
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Neal Asher
Neal Asher@nealasher·
@GrindItOut Most of the world has no idea about anything, which is why they are such easy targets for the bullshit of politicians and the legacy media.
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Rake
Rake@GoForRake·
@EliBenSasson L2s should be completely invisible to users, complete interop that's seamless. No one should have to think about what network they're sending to. Extremely bad UX for anyone that's not a crypto nerd.
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Rake
Rake@GoForRake·
For the vast majority of humanity, the only thing that matters is price appreciation. We can moralize this all we want and it won't change a thing. If the price appreciates, people will care and the network will grow. If it doesn't, the crypto nerds like us will care and the world at large will not. It's a tough world out there, and if people are going to invest their hard earned money in an extremely speculative asset, they'll have expectations of hefty returns to match that risk.
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wishful_cynic
wishful_cynic@EvgenyGaevoy·
I've seen a lot more people dunking than celebrating and it makes sense, after all most of us in crypto "pivoted" to be absorbed by the existing world machine. I also don't think most of the commentators made it past the blog post to the actual manifesto/mandate, just a sign of times I guess, clicking one extra link and spending time to read through is tough. On a more serious note, EF currently is the only player with both the resources and network effects to not just keep cypherpunk dream alive but also to actually make it happen. Will this accrue to eth price wise short term? Certainly not. Will it accrue to it long term? Only if it wins (and wins under the conditions it set for itself, not because of being adopted by tradfi). Should we care about price at all? Personally think the goal here is more important I absolutely think that we should have somebody at least trying this on grand scale instead of pursuing financial applications (and I’m pretty aware how funny it must sound from CEO of prop trading firm that made it from financial applications of blockchains🙃). Rest of us can do what they do and choose to hold eth or not. If I’m honest, holding it is a very long shot, but there are way worse cults out there, so I’ll keep my eth for the culture and memes🫡
Ethereum Foundation@ethereumfndn

Today, the Foundation’s Board released the EF Mandate. This document, which was first intended for EF members, reaffirms the promise of Ethereum, and the role of EF within this ecosystem.

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Rake
Rake@GoForRake·
It's interesting that removing medications has a meaningful (positive) impact on mortality in some populations. As a society, we really are overmedicated—which I know is a hilarious thing to say as someone who experiments with every sketchy compound under the sun. Full study + my thoughts: conquermortality.com/p/dangers-of-p…
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Rake
Rake@GoForRake·
@johnrobb Almost like you know what you're talking about or something...
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John Robb
John Robb@johnrobb·
Brave New War (2007) Premise: Rapidly advancing, relatively inexpensive, and globally available technology will offer small groups (terrorists -> small states) extreme leverage in warfare. To maximize leverage these groups will focus on disrupting networked systems (max ROI). Decentralized use of this technology maximizes survivability. This development will unwind globalization by disrupting the networked systems that it relies upon.
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Rake
Rake@GoForRake·
@gainzy222 As long as it's not a plastic cup. But better to just chug water + rehydration packet beforehand.
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gainzy
gainzy@gainzy222·
bringing a cup of water to the sauna
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Rake
Rake@GoForRake·
Google LLM as an answer engine and paid business directory, and then Reddit, X, and the other social sites for UGC. Wipe out all the blogs and niche sites (already started with HCU), which haven't been very profitable for Google's customers (investors) in a while now anyway. I guess we'll see!
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