Andrew

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Andrew

Andrew

@HayesScience

Scientist and Researcher. Molecular and cellular biology with a smattering of microbiology, biochemistry and bioinformatics.

Melbourne, Australia شامل ہوئے Mart 2019
91 فالونگ84 فالوورز
Andrew
Andrew@HayesScience·
Great to be a part of this work! If you have a pangenome from your favourite bacteria with some closed genomes (made with Panaroo/ Roary) would recommend running it through Corekaburra github.com/milnus/Corekab… to see what structural variation you find
Mark_Davies_Lab@MDaviesLab

Excited to share our new lab work - driven by our fantastic PhD student (now Dr) @magnus_gj with @HayesScience @syctong: Cataloging of chromosomal inversions in #StrepA reference genomes. Sets an analytical framework for investigations in other pathogens. academic.oup.com/nar/article/do…

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Mark_Davies_Lab
Mark_Davies_Lab@MDaviesLab·
Pleased to share our latest collaborative research on the genomic epi of typhoid fever in Fiji published in @MicrobioSoc. Wonderful collaboration with public heath parters in Fiji/Aus. Evidence of 'selection' in the S. Typhi Vi capsule locus. microbiologyresearch.org/content/journa….
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Andrew
Andrew@HayesScience·
Great to see this piece of work out! Was great to collaborate with @tim_barnett1, @KalinduRodrigo and others on this study. Some interesting implications for the detection of AMR in laboratory conditions. Would recommend checking out Tim's thread here with the paper summary.
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Magnus Jespersen
Magnus Jespersen@magnus_gj·
Magphi is v2.0.0! (github.com/milnus/Magphi) What it new? 1. @HayesScience has implemented tblastn, allowing amino acid seeds as input! 2. fasta and Gff outputs will by default be oriented to have the same strand and start site, for easier passing to alignment tools.
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Andrew
Andrew@HayesScience·
Particularly useful when extracting #phage or operons from genomes where the flanking genes are known but might not be conserved enough for an in silico PCR approach. It also works with gff files to keep your annotations so you don't need to re-annotate your extractions.
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Andrew
Andrew@HayesScience·
Great to see this published! Excellent work by @magnus_gj in making something that has saved me hours of work already! Magphi can be found at github.com/milnus/Magphi and is easily installable on conda so definitely worth checking out if you are ever extracting genes from genomes!
Magnus Jespersen@magnus_gj

Very happy to finally see Magphi published! A tool to extract annotations and sequences between two seed sequences across multiple genomes. It was build out of @HayesScience's and my necessity to extract mobile elements, but we hope others find it useful! doi.org/10.21105/joss.…

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Andrew
Andrew@HayesScience·
@aimeehorsfall I saw a video recently which explained exactly this! In brief compression of sound (to save money) is optimised to speech but doesn't deal well with music. Better explained in the link. youtu.be/w2A8q3XIhu0
YouTube video
YouTube
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Aimee Horsfall
Aimee Horsfall@aimeehorsfall·
Why is it that “on-hold music” always sounds like an old transistor radio playing next to the phone… 📞🎶
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