Mehle Lab

@CVRHutchinson @CVRinfo @RichardJOrton @CVR_Genomics @_chris_brooke And now we're live! Open access for the final version. academic.oup.com/nar/advance-ar… Thanks again @CVRHutchinson @_chris_brooke and Alistair Russell labs.

@MollyOhainle Thanks. We talked about this how many years ago? Glad we could cite your work and show how TRPPC complements your PIKA approach.

@MehleLab Love the approach ;). Congrats!

We love genetic approaches to define virus:host interactions. Knockout screens are powerful, but...technical constraints limit what you can find. Could we devise a screen where viral fitness pinpoints the key regulators of replication? (spoiler - yes cell.com/cell-host-micr…) 1/10

Find more here 10/fin. twitter.com/cellhostmicrob…

This was the result of tenacious work and deep thinking by Cason King, and offers a legacy that reflects who he was as a scientist. I thank other lab members and our collaborators in the labs of Judy Smith and @LangloisLab, and @BWFPATH for supporting risky science. 9/10.

Bittersweet final lab meeting with Jordan Ranum (white shirt). Jordan is off to med school at UW Madison. He joined as an undergrad and stayed as a scientist. Watch out for his amazing project on defective viral genomes that is about to drop.

@_colm_ @UWMadisonMDTP 🤷‍♂️ Gotta leave something bigger for the PhD defense.

It's been a busy work for the lab. Thomas (holding 🍾) passed his @UWMadisonMDTP qualifying exam with aplomb. Very excited to see him tackle his project as a dissertator. Congrats Thomas.

Excited to announce the successful thesis defense by newly minted Dr. @graceschaack (seen riding her thesis gift, a T-Rex). Great public presentation and closed-door defense. Super proud to have her as a lab alumna, and returning to the clinic to complete her MD. Congrats!

Congratulations to CMB Alums, Mitch Ledwith and Dan Tremmel, the 2022 Raymond L. Erikson Exceptional Thesis Award recipients! 🎉

@alimkell @BakerLabLBRI Fascinating topic. Great to see this @BakerLabLBRI. Congrats, and perfect launching pad for your group.

@BakerLabLBRI Woohoo!! Straight from the bottle, good work Baker team!

Very proud to share the first publication from the group 🥺 Josh & Brent co-author our review that shows The Splice is Right (host alternative splicing during viral infection) authors.elsevier.com/a/1gWwn3si8Puy…

@virusninja @nyuniversity Thanks Ben. Fun day with an impressive group of microbiologist and thoughtful and engaged students. Learned a lot and really enjoyed the visit.

For anyone looking for a great speaker to discuss virus-host interactions during influenza A virus infection, few do it better than Andy Mehle who delivered a great seminar ⁦⁦@nyuniversity⁩ today. mehlelab.com/people/andy-me…

Studying how #influenza virus engages the cellular environment, @bakerlabLBRI @MehleLab &co find that host cells use #AlternativeSplicing to embed #antiviral proteins in #metabolic enzymes, protecting host defenses from viral countermeasures #PLOSBiology plos.io/3VnlJS1