Grace Schaack
50 posts
Grace Schaack retweetledi
It's been a busy work for the lab. Thomas (holding 🍾) passed his @UWMadisonMDTP qualifying exam with aplomb. Very excited to see him tackle his project as a dissertator. Congrats Thomas.
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Grace Schaack retweetledi
Finally a gift to rival the ceremonial swords given by some unis
Mehle Lab@MehleLab
Excited to announce the successful thesis defense by newly minted Dr. @graceschaack (seen riding her thesis gift, a T-Rex). Great public presentation and closed-door defense. Super proud to have her as a lab alumna, and returning to the clinic to complete her MD. Congrats!
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Grace Schaack retweetledi
Congratulations to CMB student, Rodrigo Ibarra, whose presentation won 1st place at the Fulbright Seminar in Boston!
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Grace Schaack retweetledi
Thrilled to share that our review on bacterial G-quadruplexes is now online! Thankful for my lab mate and friend @SarahMcMillan05 who wrote this review with me! tandfonline.com/doi/full/10.10…
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Grace Schaack retweetledi
Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks
@kaaamato @mehlelab @tcflab @UWMadisonMMI
#influenza #flu #virology
go.nature.com/3PqiuXw
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Grace Schaack retweetledi
New preprint📢 We created *really* diverse libraries of barcoded #influenza viruses & used them to track viruses in hosts. We found multiple narrow within-host bottlenecks → genetically distinct "islands" of infection in a single host. Check it out⬇️ biorxiv.org/content/10.110…
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Grace Schaack retweetledi
What factors shape evolution of influenza virus within an individual? Happy to share our collaborative work led by @kaaamato with Luis and Kat and @tcflab, @SSCLabQuips, and @KoelleLab that shows genetic bottlenecks restrain intrahost influenza virus evolution. 1/10
bioRxiv@biorxivpreprint
Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks biorxiv.org/cgi/content/sh… #bioRxiv
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Grace Schaack retweetledi
Hello world! The Baker Lab is opening in mid October, 2021 at @LovelaceBio in ABQ, NM. Excited to keep serving up research on influenza, host-switch, and alternative RNA splicing. Actively recruiting an experienced technician & postdoc: thebakerlab.com/opportunities
#LoveVirology
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Grace Schaack retweetledi
Excited for the lab to present our latest at #ASV2021. intra-host transmission dynamics by @kaaamato W13-7; and host factors by @BakerVirusMaker W34-6, @GraceSchaack W34-8, @casonthemason W34-9.
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Grace Schaack retweetledi
Questions about COVID-19 vaccines? Get answers at free COVID-19 Vaccine Education Town Halls sponsored by American Society for Virology and American Society for Microbiology. Please RT and share widely asv.org/education @ASMicrobiology
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Grace Schaack retweetledi
New work led by @BakerVirusMaker: What happens when host cells dual purpose critical genes with cryptic antiviral function? Viruses are forced to “choose” between two bad options – suffer the antagonism or attack the essential gene and limit resources to make progeny. 👇🧵1/7
bioRxiv Microbiology@biorxiv_micrbio
Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus biorxiv.org/cgi/content/sh… #biorxiv_micrbio
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Grace Schaack retweetledi
So excited it's finally in print!
We worked hard to characterize patterns of #SARSCoV2 transmission in Wisconsin this past spring.
Check out what we found here⬇️
@GageKMoreno @KasenRiemersma @tcflab @dho 1/
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Grace Schaack retweetledi
Fantastic news for a fantastic scientist, mentor and leader with vision @doudna_lab. An amazing pair.
The Nobel Prize@NobelPrize
BREAKING NEWS: The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”
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Grace Schaack retweetledi
We want to reach even more early-college and high school students to let them know about programs and careers in #research and #medicine. Let us know how we can connect! #diversityinSTEM #IndigenousInSTEM #BlackInSTEM #LatinosInSTEM #LGBTQInSTEM
#WomenInSTEM #DisabledinSTEM
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Grace Schaack retweetledi
Our paper is now live at PLOS Pathogens. Several new polymerase structures came out since we submitted, and we were happy include these and discuss the potential impact of phosphorylation, especially on template exit channel formation. journals.plos.org/plospathogens/…
Mehle Lab@MehleLab
@PUNusualSuspect makes our next step in understanding how phosphorylation directly controls the influenza virus polymerase. Spoiler alert - we find a phosphosite that specifically represses transcription while leaving replication intact. Great collaboration with Coon lab again.
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Grace Schaack retweetledi
Excited for our paper on influenza virus and IFIT2 now at @NatureMicrobiol : A mystery in 3 parts where things aren’t always what they seem. It has something for everyone, with CRISPR screens, CLIP-Seq, ribosome profiling, and ribosome pausing. 1/n
nature.com/articles/s4156…
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Grace Schaack retweetledi
We have been working hard to characterize #SARSCoV2 in #Wisconsin, USA. Our work is being peer reviewed now, but our preprint is available here: medrxiv.org/content/10.110…
Here is what we have learned about #SARSCoV2 in WI:
THREAD (1/8) @GageKMoreno
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Grace Schaack retweetledi
Just out: preprint of study on face covering use in WI grocery stores during #COVID-19 shows only 41.2% of people wearing masks, need for interventions to ⬆️use. By entire 1st-year @uwsmph @UWMSTP cohort w/mentoring from Dr. Nasia Safdar. Read & comment: ow.ly/dvYM50AcFS5
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