Stefan Rothenburg

(1/6) Our new paper is out (OA): Host species-specific activity of the poxvirus PKR inhibitors E3 and K3 mediate host range function | Journal of Virology journals.asm.org/doi/10.1128/jv… It took 15 years from our initial discovery that human and mouse PKR were sensitive, whereas ...

New publication from my lab further elucidated the molecular basis for the host and virus-specific inhibition of PKR. mdpi.com/3608128

Our new manuscript is out @jvirology where we review IFN-independent antiviral responses! Mammalian innate antiviral defenses: beyond interferon | Journal of Virology journals.asm.org/doi/10.1128/jv…

The right way to remember Jim Watson is to remember him honestly. He was a central figure in one the 20th century's most impactful scientific discoveries, in the creation of modern molecular biology, in the beginning of the genomics era, and (less notably) to shaping the structures of contemporary academic departments and institutions. His actions with respect to Rosalind Franklin are certainly not beyond reproach, but the reduction of him in many peoples' minds to someone who stole her discovery is unfair and does little service to the truth. He could be charming and insightful in person, but also quick to demean people around him for seemingly no other reason than that he could. He spoke out frequently against unscientific thinking, yet also frequently said things that were unambiguously - and it often seemed intentionally - sexist, racist and anti-Semitic. The talk I saw him give at Berkeley 20 ish years ago, while perhaps designed primarily to provoke, was a masterclass in how to undermine your own reputation as a person and a thinkier. His demise was sad, but also self-inflicted in a way that someone as smart as he thought he was should have known to avoid. I know many won't mourn him - and that is fine - but I will because I think he and his generation of scientists made science a more interesting - if not always a better - place.

Great paper investigating the functional and structural basis for specific translational regulation of host and viral mRNAs during poxvirus infection. The most rewarding aspects of my job are when former trainees excel. #citeas" target="_blank" rel="nofollow noopener">nature.com/articles/s4156…

Poxvirus structural biology for application to vaccine design sciencedirect.com/science/articl…

@adamcancryn @KindrachukJason x.com/rothenburglab/…

News: HHS has no plans to rehire 20 percent of the employees it fired earlier this week, despite RFK Jr.'s assertion yesterday that doing so was "always the plan." "No such plan is in the works," a person familiar w/ the department's planning tells me. politico.com/news/2025/04/0…

For all the doubters. Here you have it. Stay strong 🇺🇸. “ONLY THE WEAK WILL FAIL”! abcnews.go.com/Politics/live-…

🚨 Big news! Infection and Immunity is now open access! 🌍🔬 That means wider visibility & impact for your research. Worried about fees? 💸 Check out how IAI stacks up against other journals—you might be surprised. #OpenAccess #SciComm #Microbiology

Timely review from poxvirus gene regulation expert Zhilong Yang and colleagues. #poxviruses Temporal expression classes and functions of vaccinia virus and mpox (monkeypox) virus genes | mBio journals.asm.org/doi/10.1128/mb…

Important paper demonstrates host-species specific inhibition of IFIT1 by different #poxviruses. A poxvirus ankyrin protein LSDV012 inhibits IFIT1 in a host-species-specific manner by compromising its RNA binding ability: dx.plos.org/10.1371/journa…

Thrilled to share our latest manuscript evaluating exon skipping ASO strategies for CF! Years of hard work and fantastic collaboration, we are so happy to finally have this work published! @HastingsLab @CF_Foundation academic.oup.com/narmolmed/arti…

My webinar on mpox and new vaccine development is Nov 26th @GlobalVirusNews @aaas @AmerSocVirol #mpox #vaccines @ASMicrobiology hstalks.com/webinar/5832/

Just re-upping this piece. No particular reason...youtube.com/watch?v=1gUP_4…

📅 Join the Global Virus Network #webinar on November 26, 2024, with Dr. Tony Schountz, professor at Colorado State University! 🦇Topic: Jamaican Fruit #Bats as an Experimental Model for #Virology and Immunology ❗️ Register here: t.ly/0f6m- @GlobalVirusNews

Your hitchhiker's guide to microbiome studies: journals.asm.org/doi/epub/10.11…

Alaskapox virus is now called borealpox virus! Fatal borealpox in an immunosuppressed patient treated with antivirals and vaccinia immunoglobulin — Alaska, 2023 academic.oup.com/cid/article/do…

New preprint from Gammon Lab @UTSWMedCenter where bacterial effectors reveal a role for mammalian RNF214 proteins in antiviral immunity in bats and humans! Great collab with the Alto Lab! biorxiv.org/content/10.110…

Are you a clinical trainee interested in undertaking a PhD in virology? 🩺🦠🧬🔬🧫 A 3-year Clinical PhD Fellowship available @CVRinfo Aug 2025 Programme details, inc current fellows: gla.ac.uk/research/az/cv… Apply: bmj.com/careers/job/21… Closing date: 26 Nov 24 Pls share🙏

Thanks to my dear colleagues from Düsseldorf and Freiburg we were able to characterize a cluster of Mayaro #virus 🦠 infection in four members of a film crew during a stay in #Suriname 🇸🇷 . Please consider #Mayaro fever in the differential diagnosis of returning travelers from the Amazon basin with fever, rash and persistent arthralgia. #arbovirus @hans_kluge @Chikwe_I @WHO_Europe @pahowho eurosurveillance.org/content/10.280…

Our newest out: Shifting gears - after great #mitochondria mtg in Spain #CSMito2024 @CellSymposia - just like we found with metabolism & antiviral responses; cheers to @PLOSPathogens for investing in our work #utswmed journals.plos.org/plospathogens/…