Sierra Simpson

Really excited for our review from @brainaddiction’s lab on #SUDs and #microbiome w/ @riomclellan & @emmawellmeyer. From #alcohol and #opioids to #psychedelics and #cannabis - it’s so exciting to see the field grow! Lots of great work out there. tinyurl.com/Suds-and-bugs

Loving the panel demonstrating that #cimm2024 never fails to have diverse speakers! A surprise all-women panel discusses gender balance and the importance of culture in meetings to promote diversity.

Feeding my #microbiome at #cimm2024 lots of veggies!

Excited to be at #cimm2024! Looking forward to three days of excellent #microbiome talks ranging from clinical to agricultural - such a well-rounded meeting that leaves me full of ideas!

If you enjoy bile acids, then this will be a fun read and a resource for you. It shows that we can begin using untargeted metabolomics big data mining using a mass spec query language to discover new molecules in animals and humans. cell.com/cell/fulltext/…

@JSADJournal @TheErinCalipari @jfcryan @TedDinan @OfMiceAndMinds @brainaddiction @SensJonathon @SophieLeclercq8 I believe that we can certainly use the microbiome to predict SUD susceptibility and severity, and use microbes and their metabolites to modulate drug intake.

Could the gut give rise to alcohol addiction? Microorganisms in the gut might make a person more vulnerable to substance-use disorders @TheErinCalipari @jfcryan @TedDinan @OfMiceAndMinds @brainaddiction @SensJonathon @SophieLeclercq8 @SierraSimpson nature.com/articles/d4158…

@KiralyLab @NIDAnews Congratulations!!!!

More big news from the lab! We are pleased to announce that we have recently received funding from @NIDAnews for an R01 studying the role of the gut microbiome in cocaine seeking and transcriptional control in the brain. We are hiring at all levels, so please be in touch!

@brainaddiction So cute! Same smile 😃

15 years apart and some things never change, Liam’s dimples and the ability of the Padres to lose a game they were winning #gopadres #memories

Delighted to share some of my dissertation research from my time in @KiralyLab! We examine the effects of microbiome and metabolite manipulations on a rat IVSA model of cocaine-seeking after abstinence.

Thomas Schmidt is dropping the mic about how we should think about the #ecology of the #gut like colonizing a volcanic island. I’m obsessed.

@gibbological explained flux balance in the most elegant way that I’ve ever seen #microbiomemovement #microbemath

@wearkizik will there ever be a lilac Lima? 💜💜💜💜

Janelle Ayres and @grischachen find pairing specific diets with diarrheal disease-causing bacteria creates lasting immunity in mice—w/out symptoms of the illness. Their discovery may lead to a vaccine for diarrheal infections in humans @ScienceAdvances bit.ly/3p3UQZy

So amazing that it is reasonable to do 100 trillion MS/MS comparisons for a single project now.

ChatGPT is expected to replace 4.5 million U.S. jobs. Apple, Google, Meta and Amazon are no longer hiring and announcing mass layoffs. If you have a phone & Wi-Fi, this is your chance to start a digital business with AI. Here is one business model that you can start today:

ChatGPT is everywhere, and everyone is using it. But AutoGPT will be the next big thing in AI. Here's everything you need to know about AutoGPT:

ChatGPT is so last month 😴 🔥 Stanford/Google researchers just dropped some mindblowing new research on generative agents, and it's like they brought Westworld to life. 🤖 Here's what you should know⤵️⤵️⤵️ Using a simulation video game they created, researchers made 25 characters that could: Communicate with others and their environment 💬 Memorize and recall what they did and observed 🧠 Reflect on those observations 🤔 Form plans for each day 📅 Then, they gave them some memories: An identity (name, occupation, priorities) 📝 Information about/relationships with other characters 💑 Some intention about how to spend their day 💭 Then, they pressed play. ▶️ With just this information alone, the characters acted much like humans do: They shared information with each other 🗣️ Example: Isabella starts the day with a plan to host a Valentine's Day party. She spreads the word, and by the end of the simulation, 12 characters know about the party 🥳 Much like humans, 7 of them flaked - 3 of them had "other plans" and the other 4 just didn't show. 😒 They form new relationships and remember them 💞 Example: Sam and Latoya don't know each other at the start. They meet at a park, and Latoya says she's working on a photography project... 📸 When Sam and Latoya meet again later, Sam says: "Hi, Latoya. How is your project going?" 📷 They coordinate with each other 🤝 Example: Researchers gave Isabella (the v-day party host) and Maria two pieces of info: Isabella: You will throw a party 🎉 Maria: You have a crush on Klaus 💘 Without any further instruction, Isabella invites people to the party, decorates the venue, and asks Maria for help. Meanwhile, Maria jumps at the opportunity to get closer to Klaus by inviting him along as well. 😍 This is fascinating new research 📚 We've officially moved past 'AI models can write blog posts for me' and into "How much can AI models act like humans?" territory. 🤖➡️👫 We're moving fast 💨. Paper - arxiv.org/abs/2304.03442 Credit - @nonmayorpete

AutoGPTs are improving at a blazingly fast speed and could soon transform the face of business. Here's what you need to know:

These graphics summarize some of life's hardest lessons. 1/ Distractions fill the space we give them.

After a patient saw multiple physicians and neurologists over 6 months and was assigned a diagnosis of #LongCovid, a relative entered her symptoms into #ChatGPT with the correct output. Diagnosis was confirmed by antibody testing and therapy has been initiated.

Registration is open for our next virtual symposia on Visceral Pain: What’s the latest? 4/16/23 @ 6pm EST Moderators: Brian Gulbransen, PhD & Elyanne Ratcliffe, MD Speakers: Alan Lomax, PhD & Stuart Brierly, PhD us06web.zoom.us/webinar/regist…