Xiao Li ری ٹویٹ کیا
Spatiotemporal gene expression and cellular dynamics of the developing human heart
nature.com/articles/s4158…
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Xiao Li
135 posts
Xiao Li
@SirScienceAlot
Asst. Professor @Texas_Heart at Baylor College of Medicine | Cardiac biology, Immunity, Genomics | Love outdoor photography, all living things | Views’re my own
Houston, TX شامل ہوئے Şubat 2023
176 فالونگ128 فالوورز
Our new study with the Martin Lab uses spatial single-cell omics to dissect the cellular architecture of cardiac fibrosis in the atria. Grateful for a great collaboration and congratulations to Chang-Ru and the team! 🎉
Chang-Ru Tsai@ChangRuTsai1
Excited to share our latest work! Thank my mentor @jmartinlab and all the colleagues @linliucns, @RichGangLi , @Fansen2020 and collaborators @SirScienceAlot and Dr. Jun Wang and Dr. Hassan Samee. ahajournals.org/doi/full/10.11…
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Xiao Li ری ٹویٹ کیا
Congratulations to the team! Another piece of our pediatric HF studies
H.J. Tadros@hj_tadros
Excited to share our @Circ_Gen article profiling end stage hypertrophic cardiomyopathy 🫀in 👶🏻 with snRNA-seq 🧬 ahajournals.org/doi/10.1161/CI… Thank you to our team @jmartinlab , @SirScienceAlot , @DiwakarTuraga #CardioTwitter #Genetics @TCHheartcenter @BCM_CVRI
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Interesting concept👍
Xu Zhou (周旭)@XuZhouLab
Glad that our paper is officially out @CellCellPress. BRD4 condensate functions as a pH sensor to tune inflammatory response in macrophage. cell.com/cell/fulltext/… earlier post: x.com/XuZhouLab/stat… and could-have-been cover by my student&artist Cathleen Krabak @harvardmed
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Xiao Li ری ٹویٹ کیا
PSA: Stop calling macrophages in tissue M1 or M2. These are not states that exist in biology. The only use of M1 is a macrophage cultured ex vivo with LPS and IFNg; and for M2: IL-4/13/10. Macrophages in tissues are highly complex and diverse and do not resemble either of the aforementioned M1/M2 states. M1/M2 language causes confusion and sets the field back. Refer to your macrophages by the molecules they express and the cytokines they make.
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Xiao Li ری ٹویٹ کیا
Spatial-DMT is now published in @Nature ! For the first time, we can simultaneously map DNA methylation and RNA transcription in tissue context. Great collab with @zhouwanding lab. Big congrats to Chin @Chin72155594 , Hongxiang @HongxiangFu and team! nature.com/articles/s4158…
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Xiao Li ری ٹویٹ کیا
With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency | Science | AAAS science.org/content/articl…
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Game changer for functional genomics!
Jun Cheng@s6juncheng
Excited to share #AlphaGenome, a start of our AlphaGenome named journey to decipher the regulatory genome! The model matches or exceeds top-performing external models on 24 out of 26 variant evaluations, across a wide range of biological modalities.1/6
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A key post-transcriptional mechanism in pediatric cardiomyopathy. Congrats to the Jang Lab🎉🎉🎉
Jihyun Jang@JihyunJang_JJ
Our lab’s first discovery is out today! We identified cardiac m6A methyltransferases as a novel gene regulatory layer in heart development. More mechanisms await discovery! @Deqiang8 @AccorneroLab @heewlim @ViduGargMD @SirScienceAlot ahajournals.org/doi/10.1161/CI…
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Xiao Li ری ٹویٹ کیا
Research| Jimenez et al. show that CD40 agonists can induce myocardial inflammation by activating cardiac macrophages and CD8 T cells, sensitizing the heart to secondary injury and promoting adverse remodeling.
👉rdcu.be/ehHlK
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Xiao Li ری ٹویٹ کیا
Xiao Li ری ٹویٹ کیا
An Australian man in his forties has become the first person in the world to leave hospital with an artificial heart made of titanium
The device could be a temporary measure for those waiting for a donor organ
go.nature.com/41sHfKw
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Thrilled to share that I received @American_Heart
AHA Career Development Award. This is very important to me at this special time. I'd like to thank my incredible mentors @williampu66 @Jon_Seidman, collaborators @Sarah_Morton @PuLab, and AHA reviewers for their strong support!
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The Sweat lab will be opening at UTSW, the Moss heart Center, in September!
Research topics include AFIB and cellular identity programs.
I'm grateful for this opportunity, made possible by support from my family, amazing academic mentors, and the wonderful Moss Cntr. Faculty!
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I'm thrilled to share that our lab has officially received the NOA for our first R01 today!
We are eager to dive deeper into RNA biology during heart development. I’m so excited for the journey ahead and can’t wait to share the discoveries to come.
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Xiao Li ری ٹویٹ کیا
At a critical time for scientific research, the new American Heart Association Presidential Advisory emphasizes medical & economic benefits of @NIH funded research
newsroom.heart.org/news/a-strong-…
@AHAScience @HeartNews @StanfordCVI @American_Heart @StanfordMed @CircAHA @HeartBobH
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