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Do you call CRISPRs in bacterial genomes or MAGs using CRT (or a tool based on CRT)? Read my blog post on a common #CRISPR annotation error and a fix with #Rstats:
albertvill.com/posts/crt_repe…
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Albert Vill
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Albert Vill ری ٹویٹ کیا
Is it “winner-takes all” when the simplest living things compete? Check out my fresh publication on phage coexistence in Science and a thread below🧵 science.org/doi/10.1126/sc…
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Albert Vill ری ٹویٹ کیا
.@AntaniJo (@Yale) etal developed a microscopy-based technique to measure #phage attachment to bacterial cells. This method provides an alternative to the century-old Phage Adsorption Assay. Feel free to reach out with any questions: jyot.antani@yale.edu.
buff.ly/4fd1PnD
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Albert Vill ری ٹویٹ کیا
Finally, the preprint on my postdoc work from the past 3 years! With mentorship from @PaulTurnerLab and @EmonetLab, I developed a microscopic technique to measure attachment of viruses #phages to bacterial cells @YalePhage @QbioYale .
biorxiv.org/content/10.110…
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Albert Vill ری ٹویٹ کیا
I'll be speaking about viral sociality at TEDxNewEngland on Wednesday 25th September, alongside a great lineup of other speakers.
List of speakers & tickets here for anyone in the Boston area who might want to come: tedxnewengland.com/speakers
#TEDxNE #SocialViruses #LoveVirology
Old TEDxNE Account@TEDxNE
Asher Leeks is pushing the boundaries of biomedical science with his innovative research on sociality in viruses🦠. To hear more about @AsherLeeks' approach to the future of viral research, attend our inaugural MIND+LIFE conference on 9/25. Info in bio. bit.ly/3zhSMSF
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Albert Vill ری ٹویٹ کیا
I’m super excited to announce my new position at @Harvard_Law working for Hannah Shaffer and @emma_k_h!
I think my long-sleeved Crimson jersey will be too warm in San Diego, but Yale Blue will always have a spot in my rotation. Whenever I’m not repping Tritons, that is! 🔱🌊☀️
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Albert Vill ری ٹویٹ کیا
Hey #Evol2024! Interested in the evolutionary ecology of host-parasite interactions? Come check out the presentations by my amazing trainees, listed below!
I'll give a brief preview of each presentation below 🧵
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Albert Vill ری ٹویٹ کیا
I am absolutely delighted to be joining the University of British Columbia next year as an Assistant Professor @ZoologyUBC.
We will study social evolution in viruses.
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Albert Vill ری ٹویٹ کیا
Pangene now published in Bioinformatics: doi.org/10.1093/bioinf…. In addition to showcasing applications (see the 17q21.31 inversion below), we also reviewed the theoretical formulation of bidirected graphs and discussed the definition and the finding of "bubbles" in such graphs.
Heng Li@lh3lh3
Preprint on Exploring gene content with pangenome gene graphs: arxiv.org/abs/2402.16185. It describes pangene for building gene graphs and for calling gene-level variations which can be found at pangene.bioinweb.org. Pleasant collaboration with @maxgmarin and @MahaFarhat.
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Albert Vill ری ٹویٹ کیا
Kamala's mother immigrated from India to pursue a PhD & stayed to work as a cancer researcher
Kamala's father immigrated from Jamaica to pursue a PhD & stayed to work as a professor
Immigrant scientists contribute not only to science but to society at large -- for generations
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Albert Vill ری ٹویٹ کیا
Benchmarking is ongoing (wait for the preprint coming soon!), but comparing to Pharokka, on 179 genomes assembled with @viji112's Phables (github.com/Vini2/phables), Phold dramatically increases the annotation rate (5/n)
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Albert Vill ری ٹویٹ کیا
A dynamic subpopulation of CRISPR–Cas overexpressers allows Streptococcus pyogenes to rapidly respond to phage | Nature Microbiology nature.com/articles/s4156…
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Albert Vill ری ٹویٹ کیا
Albert Vill ری ٹویٹ کیا
1/ 🧵 Thrilled to share work of @EligoBio just published in @Nature ! We show proof of principle results of efficient base editing performed on E. coli directly in the mouse gut 🦠💡 #Microbiome #SyntheticBiology nature.com/articles/s4158…
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Albert Vill ری ٹویٹ کیا
📣Calling all #microbiome enthusiasts!
join our eco-genomic team @bengurionu to unravel microbial community secrets. We're a fun, collaborative group seeking a talented #postdoc & #PhD with #microbiology or #bioinformatics experience. Be part of the microbiome revolution!🔬🦠🧬
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Albert Vill ری ٹویٹ کیا
Our paper! 🪩
"Spatial mapping of mobile genetic elements and their bacterial hosts in complex microbiomes"
Full text link:
doi.org/10.1038/s41564…
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Albert Vill ری ٹویٹ کیا
Very excited to announce I’ll be joining @UofSCBiology as an assistant research professor through the Bridge to Faculty program! Looking forward to using this time to prep for the opening of the Lewis Lab in 2 years😊. #newpi
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Albert Vill ری ٹویٹ کیا
Spatial mapping of mobile genetic elements and their bacterial hosts in complex microbiomes | Nature Microbiology nature.com/articles/s4156…
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Albert Vill ری ٹویٹ کیا
Pseudomonas partners with Pf phage to build biofilms and promote antibiotic tolerance. Here, we explore how. Congrats to Kevin Chen, @cai_pam @PRSecor, @heilshornlab @ASpakowitz @ebburgenerMD and a terrific team science.org/doi/10.1126/sc…
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Albert Vill ری ٹویٹ کیا
I am super excited to share our latest manuscript on the origin and renewal of the gut lacteal musculature from villus myofibroblasts! 🎉
Link: sciencedirect.com/science/articl…
Check out @BSanketi's thread for details!
Bhargav Sanketi 🧬@BSanketi
Finger-like projections in our gut, the villi enable us to absorb nutrients from our diet. 🚨🚨 Our collaborative paper out today @Dev_Cell describes the origin and regeneration of the intestinal fat absorption apparatus. 🧵 @mantri_madhav @KurpiosLab @IwijnDeVlaminck @Cornell
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Albert Vill ری ٹویٹ کیا
💥Our new preprint!
Transposon ADDICTION in development!
Gag proteins of endogenous retroviruses are required for zebrafish development
Study led heroically by @sylviaandbu & @JN_Wells
This work has transformed my view of transposons, no less! 🧵1/n
biorxiv.org/content/10.110…
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