CronosMcC

“La soberbia no daña a tus colegas daña a tus pacientes”

Interested in the major trials in critical care? We have summarised and critiqued 250 of the most important randomised controlled trials stretching back over the past 25 years. criticalcarereviews.com/collections/fo…

A 62-year-old postmenopausal woman presents to the ED with sudden onset chest pain and SOB that began shortly after a severe emotional stress event. What's the most likely diagnosis?

Cefepime vs Piperacillin Tazobactam (Zosyn) These antibiotics have similar but not identical coverage Main difference? Zosyn covers anaerobes while cefepime does not Zosyn has some enterococcal coverage while cefepime does not Zosyn = cefepime + metronidazole + ampicillin

Hoy vamos a hablar del #Hi-PEITHO, o como un estudio positivo se deberia tomar como negativo. PEITHO en la mitologia griega era la persuacion, el encanto y la seduccion, pero este estudio no lo logra. @NEJM.

AKI guidelines hadn’t been updated since 2012. The KDIGO 2026 AKI/AKD Public Review Draft just dropped and it changes how we define, diagnose, and follow up after acute kidney injury. Here’s what every nephrologist, intensivist, and internist needs to know 🧵 ⚠️ Public review draft only · Not yet final guidelines

AHA slides are a good tool to learn the guidelines... #MedTwitter DAPT strategies in ACS for the first 12 months

Espironolactona no es igual que finerenona: Falla en demostrar beneficio en ICFEp #LaSECteLleva a #ACC26

🧵 ¿Es suficiente la anticoagulación en el TEP de riesgo intermedio? 🤔 Un ensayo reciente del NEJM cambia el paradigma. ⭐️HI-PEITHO⭐️ Abro hilo 👇

En choque séptico con endotoxemia y falla multiorganica, el cartucho de hemoadsorción de polimixina B, comparado a lo habitual; ↓10% y ↓15% el riesgo absoluto de mortalidad a 28 y 90 días, respectivamente @javo_neyra Ensayo clínico TIGRIS🐯 Lancet 2026 doi.org/10.1016/S2213-…

🚨 ¿ "Paneles de Trombofilia" a todos los pacientes con Tromboembolismo Venoso (TEV)? 🛑 Una excelente revisión en Annals of Phlebology nos recuerda por qué el enfoque debe ser rigurosamente selectivo. Aquí te resumo las perlas para tu práctica clínica diaria 🧵👇 @GT_Trombo @CordobaETV @gabi_puchepalao @UsuarezMD @carranzajhonny1 @ricardo_bedon @ResidentesSEMI @ETVgregorio @mmartinasenjo @PabloDemelo doi.org/10.37923/phle.…

Recuerda🤔q ahora #CoEsAnt #EUCAST en #Pseudomonas I* NO significa sensibilidad intermedia si no “SENSIBLE con aumento de exposición”⬆️💊. Si I*➡️S a dosis MÁXIMA (x ejplo #Cipro 750 mg/12 h o #ceftazidima 2 g/8h) 🆓🔗 sciencedirect.com/science/articl…«I»,»%20(sensibilidad%20intermedia)2.

IMPORTANCIA #AntimicrobialStewardship #PROA en paso #ViaORAL de #antibioterapia💉➡️💊 en bacteriemia NO estafilococica🩸❌🍇 En @OFIDJournal la presencia de AShip aumentó el paso a oral 59%➡️93% conmenos días de ATB (12🆚vs. 10) y mismo fallo clínico (7%) academic.oup.com/ofid/advance-a…

Questions and issues of non-ventilated hospital acquired pneumonia: an opinion document doi.org/10.1016/j.cmi.…

Nice case report about proning Benefits in reduction of Mechanical Power, Oxygenation Index, Ventilatory ration journalmechanicalventilation.com/the-mechanical… How to calculate them? societymechanicalventilation.org/calculators/

5 studies from #ISICEM26 every intensivist should know 👇 🧬 Immune dysregulation in pneumonia & sepsis 💨 High-flow vs standard oxygen 🫁 ARF in immunocompromised patients 🩸 Prehospital whole blood in trauma 🏥 ICU restraint strategies @ISICEM

Current status of immunomodulatory therapies in adult sepsis patients: where do we stand? doi.org/10.1080/147872…

Volume outcome in cardiogenic shock: bit.ly/4s9C3Y4 just published! ⁦@SVRaoMD⁩ ⁦@AGIKinterv⁩ ⁦@KardiologieHH⁩ ⁦@ACVCPresident⁩ ⁦@HFA_President⁩

Las jerarquías en medicina

In an international, randomized trial involving patients with acute venous thromboembolism, the risk of clinically relevant bleeding was significantly lower with apixaban than with rivaroxaban during the 3-month treatment period. Full COBRRA trial results: nejm.org/doi/full/10.10…

How to safely discontinue antifungal treatment in invasive pulmonary aspergillosis? – Clinical considerations in haematology doi.org/10.1016/j.cmi.…