Rodrigo Grassi-Oliveira

Reforçando o compromisso da PUCRS com a ciência e a pesquisa no Brasil, oito pesquisadores da Universidade integraram o levantamento da plataforma Ranking Research, que destaca os cientistas de maior prestígio no cenário internacional. portal.pucrs.br/noticias/ensin…

@e_brietzke Até ressurgi das masmorras do Twitter para citar a Odete Roitman original: “Dama de circo eu detesto desde criança. Vamos Celina. Com licença minha filha, se você precisar de alguma coisa, nós estamos aqui na ante-sala”. Democratização da ciência e seus efeitos paradoxais 🤌

Olha como a coisa é perigosa! Pesquisadores decentes (Univ de Toronto) fazem uma meta-análise de dieta cetogênica na Depressão e publicam em uma boa revista! Isso justamente para EVITAR que o Dr. Integrativo pince um paper isolado e faça inferências exageradas. O que o influenciador científico faz? Cai matando em cima da meta-análise e da revista.

@Grimezsz within faith, yes: God is reliable by definition, I just don’t have it 🫣

To be honest

@Grimezsz “I contain multitudes. Do I contradict myself? Very well then, I contradict myself; I am large, I contain multitudes.” Whitman within The Life of Chuck

I feel like the only thing I can confirm is actually happening is that I love things. I can't rly trust anything besides my internal experience and pain is fleeting, which makes me feel like the only thing that exists is love

🚨 Excited to share our latest preprint: "Lipidomic and Proteomic Insights from Extracellular Vesicles in Postmortem Dorsolateral Prefrontal Cortex Reveal Substance Use Disorder-Induced Brain Changes” #ExtracellularVesicles biorxiv.org/content/10.110…

A study of 25,252 Swedish twins indicates that adverse childhood experiences associated with elevated risk of adult psychiatric disorders notwithstanding considerable familial (genetic & early environmental) confounding revealed through MZ/DZ comparisons. ja.ma/3KvvbQl

Please see this new review on Neurobiology of Resilience by @ScottRussoPhD and me which just appeared online in @NeuroCellPress. cell.com/neuron/fulltex…

Meet Professor @grassirod, group leader at the Aarhus University. In the #HappyMumsProject🤰🧠 , he will guide the investigation of the sex-specific biological mechanisms underlying offspring risk to prenatal maternal depression. #perinatalmentalhealth #horizonproject

The organism is a network of communicating, energy transforming mitochondria quantamagazine.org/cells-across-t…

We are thrilled to share our latest paper published in @NatureComms! We report that sharp-wave ripples emerge around postnatal day 10, driven by the maturation of inhibition. Brought to you by @IPochinok, @chini_mattia, Jochen Triesch, and @tristanstoeber. nature.com/articles/s4146…

🫶🏻

We profiled genome-wide DNA methylation (DNAm) of umbilical cord blood from newborns with and without cocaine exposure during pregnancy. We used DNAm data to (1) assess pediatric epigenetic clocks at birth and (2) to estimate epigenetic scores (ES) considering the large-scale DNAm data availability and existing evidence regarding prenatal cocaine exposure (PCE) as a risk for health problems later in life. We generated ES for tobacco smoking, psychosis, autism, diabetes, and obesity. PCE was associated with protracted DNAm gestational age in newborns, and this effect remained significant when controlling for potential confounders, such as blood cell type composition predicted by DNAm and obstetric data. DNAmGA was negatively correlated with BDNF levels in the serum of UCB. Higher tobacco smoking, psychosis, and diabetes ES were found in the PCE group. The GO analysis revealed GABAergic synapses as a potential pathway altered by PCE. @WViolaThiago @FriesGabriel nature.com/articles/s4159…

I am glad to announce it is official! We got the Better Framework for Psychiatry @DFF_raad grant! I can only think about I Ching Hexagram 53, Ji’an: “The best progress is slow but steady—slow enough to allow for bonds to knit properly and steady enough to keep moving in the right direction. A firmly rooted tree has deep roots and is not easily toppled.” Thanks Chioma Okeoma (NYMC), Chelo Walss-Bass (UTHealth) and @WViolaThiago (PUCRS) for the partnership!

@TWBredy @Paul_R_Marshall @AusNeuroSoc Handsome 😃

By using machine learning we found clinical and psychosocial variables that can be assessed in real-world clinical settings, potentially helping clinicians to identify individuals with severe cocaine withdrawal that is likely to be sustained over the course of detoxification.

Save the date: Meeting on brain non-coding RNAs coming up in October 2024 in beautiful Ascona, Switzerland. Impressive line-up of speakers. Registration will open in March 2024. Visit brain-ncRNA-conference.ch for more info.

Thrilled to receive the Lundbeckfonden Ascending Investigators Grant 2023! 🥳 Exploring how THC & CBD during pregnancy impact brain cells DNA & future cognitive abilities. Let’s build bridges between Aarhus University 🇩🇰, PUCRS 🇧🇷, and Karolinska Institute 🇸🇪! 🧠🔬 #THC #CBD #Neuroscience @lundbeckfonden @AIAS_dk @AarhusUni

Dan Stein 🇿🇦

Cocaine use disorder effects on blood oxytocin levels and OXTR DNAm sciencedirect.com/science/articl…