Thule Larper

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Thule Larper

Thule Larper

@thulelarper

goal: feel alive | artisanal generalist

PEC شامل ہوئے Ağustos 2019
1.6K فالونگ1.7K فالوورز
Thule Larper
Thule Larper@thulelarper·
@GeringerAdam you must have picked up some design inspo while in turkey for the transplant
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App Launcher
App Launcher@AppLauncher_App·
@thulelarper First trustpilot review is the moment a side project becomes something people bothered to open a browser tab for. That tiny friction is the real validation signal.
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Thule Larper
Thule Larper@thulelarper·
first 5 star trustpilot review on the side project signups coming in thank you claude code
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( ͡° ͜ʖ ͡°)@hmmmcurious·
Wonder if there’s some kind of cognitive thing that older people just don’t have to detect AI videos? Genuine research question
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nobody
nobody@nobody97799851·
@hmmmcurious it's because aging makes you retarded
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( ͡° ͜ʖ ͡°)@hmmmcurious·
More convinced than ever that nobody has health and nutrition figured out. When you’re a regular person, all the errors in your models at least have a chance of cancelling out.
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Thule Larper
Thule Larper@thulelarper·
Sowmay Jain@sowmay_jain

i got my whole genome sequenced two years ago and forgot about it. last week i told my ai agent (@laukiantonson) to dig up my DNA files • it dug up a two-year-old email • found the download link • pulled down 67 gigabytes of raw DNA. • rented a 32-core, 64GB machine for a few hours — total cost: $5 • aligned 21 million long reads to the human reference genome — 99.83% mapped • called 5.8 million genetic variants using a two-pass neural network • phased every variant — separated maternal vs paternal inheritance • annotated all 5.8M variants against ClinVar, PharmGKB, and gnomAD • corrected for population-specific bias in the medical literature • health risk map across 39 conditions flagged in every body system • drug compatibility guide for 141 medications color-coded by genome response • nutrient metabolism - 71 variants affecting absorption of vitamins, minerals, iron • traits, ancestry going back 40,000 years, neanderthal DNA breakdown $5 in compute. 8 hours. no bioinformatician. no doctor. just one instruction. we've genuinely reached a point where an ai agent can take your raw genome and hand you back a full personal health profile in a single shot. i had no idea this was even possible.

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Thule Larper
Thule Larper@thulelarper·
@ky__zo just make more money, then you can have the same quality of life in a real country
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kyzo
kyzo@ky__zo·
average bali cafe experience: - high quality, high protein food for $10 - sauna and ice bath at the back so hard to leave this place, life quality drops immediately
kyzo tweet mediakyzo tweet media
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( ͡° ͜ʖ ͡°)@hmmmcurious·
what coffee setup are u rockin at home rn?
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Thule Larper
Thule Larper@thulelarper·
hate to sound like a shill but chatgpt pro is actually insane for financial research questions
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The Rebel
The Rebel@RockyTheRe44006·
@thulelarper Just the diesel tank itself, not even counting the slip tank.
GIF
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The Rebel
The Rebel@RockyTheRe44006·
Over $400 to fill up my truck. WOT IN TARNATION
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J.
J.@PresentWitness_·
The primary issue with the Iran war is that it is of no consequence to Americans. We produce our own oil and natural gas. Why are we blowing hundreds of billions of taxpayer dollars, years of built up political capital, and priceless time/attention on it before the midterms?
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Will Manidis
Will Manidis@WillManidis·
tbpn board of directors (2025-2026)
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John Coogan
John Coogan@johncoogan·
TBPN has been acquired by OpenAI! The show is staying the same and we’ll continue to go live at 11am pacific every weekday. This is a full circle moment for me as I’ve worked with @sama for well over a decade. He funded my first company in 2013. Then helped us fix a serious logjam during a critical funding round a few years later. When I took my second company through YC, he was president at the time, and then when I joined Founders Fund, the first deal I saw in motion was the post-ChatGPT round in late 2022. And as we started growing TBPN last year, he was the very first lab lead to join the show. Thank you to everyone that has been a part of TBPN until now. The last year has been the most fun and rewarding part of my career and we’re excited to have more resources than ever going forward.
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Midwest Modern
Midwest Modern@JoshLipnik·
On my way to Toronto for the weekend. Let me know if there’s any newer buildings I should check out, like stuff built in the past 5-10 years.
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