Sáenz Lab

Our latest manuscript "Lipid membranes modulate the activity of RNA through sequence-dependent interactions" is... 🎉🎊 published 🎊🎉!! pnas.org/content/119/4/… @t_czer_jea @James_Saenz @PNASNews @VolkswagenSt @BMBF_Bund @SimonsFdn @BCUBE_TUDresden

Dressed for success 👯 Excited to join the Priority Programme “#Physics of #Parasitism” (#SPP2332) funded by @dfg_public to study #Plasmodium #microtubules together with @StefanDiezLab @PoLDresden & @FrischknechtLab @UniHeidelberg

Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides buff.ly/4gSQuKc (@BBAjournals)

The living world is full of fascinating discoveries, from microscopic bacteria to entire ecosystems 🦠🦬🌍 But how do we turn this vast amount of biological data into meaningful concepts? Join the 2nd edition of 'Theory and concepts in biology' to explore the interplay between theory and biology! #EESTCBio 📥 Submit your abstract by 11 February 💻 s.embl.org/ees25-03-x 🗺️ EMBL Heidelberg and Virtual 📅 6 – 9 May #biologicalphysics #theoryinbiology #physicalbiology #systembiology #physicsoflife #livingmatter

I am excited to preprint my postdoc work in the @OlzmannLab! We have discovered the first lipid droplet quality control pathway with broad implications for lipid physiology and diseases associated with LD accumulation and oxidative stress! #lipidtime shorturl.at/2HqFd

Choline was first described nearly 175 years ago but our understanding of this essential metabolite is still coming into focus. Excited to share our perspective ⁦@NatMetabolism⁩! ⁦@samscharenberg⁩ ⁦@abu_remaileh⁩ ⁦@KivancBirsoy⁩ nature.com/articles/s4225…

Out now in @MolecularCell our latest work on RNP granules spearheaded by I.R.E.A Trussina. G3BP-driven RNP granules promote inhibitory RNA-RNA interactions resolved by DDX3X to regulate mRNA translatability: Molecular Cell cell.com/molecular-cell…

Refusing an invitation in Britain: "I'd love to, but I'm afraid I can't, I have to be up early tomorrow. Seriously, it sounds like a lot of fun, but you know how it is. Perhaps we could get together next week..." Refusing an invitation in Germany: "No, I don't want to do that"

Born on Christmas Day in 1876, Adolf Otto Reinhold Windaus was a German chemist who won a @NobelPrize in Chemistry in 1928 for his work on sterols and their relation to vitamins.

Open postdoc position in Vienna: Development of a simple, yet powerful open-source MINFLUX microscope. maxperutzlabs.ac.at/news/open-posi… Please RT.

How to measure mechanical properties in just a couple of seconds, from 🐠 to #biofilm? - Optical multi-frequency time harmonic elastograthy! With Liraz Chai @lab_chai led by Jakob Jordan & Ingolf Sack @EBM_research @spp2389 @MPZ_PhysMed @ChariteBerlin onlinelibrary.wiley.com/doi/10.1002/ad…

It was a pleasure hosting you, Alisa! Hopefully by now you are addicted to minimal membranes 🤩

Join the #SorkinLab at the #TAU! 🔬 Explore how #MembraneProperties affect the formation of #BiomolecularCondensates! Interested in using cutting-edge techniques such as #AFM and #ForceSpectroscopy? Apply for our #PhDposition: comeincell.org/dc14-how-can-m… #ComeInCell #MSCA

Exciting update on this study - stop by on the blue side to learn more about it...

If you are attending #CellBio2024, check out our lab member's oral and poster presentations. @ASCBiology

Today I’m joining 30+ colleagues in taking an unusual step: calling for a halt to a line of research I was excited about, the long-term effort to build “mirror life”. We’re sharing our findings in a @ScienceMagazine paper: science.org/doi/10.1126/sc… 1/6

Preprint alert!! How zonated hepatocytes adapt to changes in lipid influx due to fasting or a Western diet (WD). We developed a microscopy-based phenotyping method called single-cell phenomics (scPhenomics) to measure the features of mitochondria and lipid droplets (LDs).

A new @ScienceMagazine article from 30+ leading international scientists including several @JCVenterInst researchers, examines the potential dangers of building ‘mirror life’ — organisms composed entirely of mirror-image biological molecules.

At SEVA, we’re all about minimalism, but @LabSaenz just raised the bar 🤯 They engineered a minimal cell membrane with just 2 kinds of lipids! If that’s enough for life, could this open the possibility of further genome reduction? 🧬 Learn more👇 buff.ly/3OLH2Mm

Super happy to have Cohen Lab PhD student Ian Windham's paper about #APOE trafficking to #LipidDroplets featured in this exciting collection!!

PhD alert! I have two ERC-funded PhD positions to uncover the chemical origins of life! Starting date: October 2025. *UK fees only*. Projects described here: lclu.cam.ac.uk/studentship-op… Email me if interested - deadline (PhD in Biochemistry, Uni of Cambridge): January 7th!