James Olzmann

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James Olzmann

James Olzmann

@OlzmannLab

Professor of Molecular Therapeutics and Metabolic Biology at UC Berkeley; Departments of Molecular & Cell Biology and Nutritional Sciences & Toxicology

Berkeley, California. USA. Katılım Ağustos 2018
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Jeremy Baskin
Jeremy Baskin@basktastic·
Excited and grateful to have been promoted to Professor. Many thanks to the outstanding students and postdocs in my lab and to my colleagues at Cornell and across the #chembio and #lipidtime communities for your continued support!
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Veijo Salo
Veijo Salo@VeijoS·
How does a cell remodel the ER membrane into a lipid droplet? Excited to share our new preprint. We find that regulated opening of the seipin ring defines a functional ER–lipid droplet interface — and identify SMLR1 as a regulator of this transition. biorxiv.org/content/10.648…
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Dan Nomura
Dan Nomura@DanNomura·
Excited to highlight our newest work on an induced proximity-based targeted transcriptional repression platform termed Transcriptional Repression via Active Chemical Epigenetic Reprogramming (TRACERs)! Congrats to @CEStieger and co-authors and our @NovartisScience collaborators!! (1/9) pubs.acs.org/doi/10.1021/ac…
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Henry De Belly
Henry De Belly@Henry_de_belly·
Very excited to be sharing our new paper, just out in Nature Cell Biology! nature.com/articles/s4155… The big question we investigate: How do migrating cells put their front 🔴 and back 🔵 in the right place?
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Rushika M. Perera
Rushika M. Perera@rushika_perera·
Our latest study out in @MolecularCell explores how and why MHC class I is aberrantly targeted for degradation via the autophagy-lysosome pathway in pancreatic cancer. Congrats to postdoc extraordinaire @marineberquez for leading this study! @UCSFAnatomy @UCSFCancer
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Molecular Cell@MolecularCell

Online Now: A multi-subunit autophagic capture complex facilitates degradation of ER-stalled MHC class I in pancreatic cancer dlvr.it/TSn7r3

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Roberto Zoncu
Roberto Zoncu@RobertoZoncu·
Very cool study by @rushika_perera lab uncovers the mechanisms of autophagic degradation of MHC-I to achieve immune masking of PDAC cells
Rushika M. Perera@rushika_perera

Our latest study out in @MolecularCell explores how and why MHC class I is aberrantly targeted for degradation via the autophagy-lysosome pathway in pancreatic cancer. Congrats to postdoc extraordinaire @marineberquez for leading this study! @UCSFAnatomy @UCSFCancer

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Abdou Rachid Thiam
Abdou Rachid Thiam@Rachid_Thiam·
Happy to share our review proposing seipin as a lipid rheostat, not just a #lipiddroplet biogenesis factor. Its flexible structure enables it to integrate metabolic cues at organelle contacts, coordinating lipid storage, membrane synthesis & signaling. hubs.la/Q04jXmy_0
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Roberto Zoncu
Roberto Zoncu@RobertoZoncu·
Excited to share our new paper: 'LASER couples damage sensing to ESCRT assembly for lysosome repair.' Congrats to dream team @clairegoul and @aakritijain24 for uncovering a new lysosome repair pathway and its connection to neurodegeneration. bit.ly/49FCPoq
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