MalDA Consortium

Out today in @CellChemBiol: genetic and chemical validation of PfAcAS as a druggable antimalarial target. Congratulations to all MalDA members on this colossal effort advancing #drugdiscovery in #malaria! sciencedirect.com/science/articl…

One of the cover stories of our June issue bit.ly/2N9R8Es: #MalDA, Accelerating Malaria Drug Discovery @MalariaTargetID @ElizabethWinze1 @baragana_b @Kelly_Chibale @LlinasLab @fidocklab @UCSDMedSchool @HarvardChanSPH @DDU_Dundee @WUSTL @GSK @MIT cell.com/trends/parasit…

Today is #WorldMalariaDay MalDA, Accelerating #Malaria Drug Discovery @MalariaTargetID @ElizabethWinze1 @baragana_b @Kelly_Chibale @LlinasLab @fidocklab @UCSDMedSchool @HarvardChanSPH @DDU_Dundee @ColumbiaMed @GSK @theGHDDI @sangerinstitute @MITdeptofBE cell.com/trends/parasit…

Hot off the press! We have identified and characterized MFR3, a novel multidrug resistance mediator in P. falciparum. Read all about it in @ACS_Infectious: pubs.acs.org/doi/10.1021/ac…

Out now in @TrendsParasitol: Learn all about how the Malaria Drug Accelerator facilitates rapid #drugdiscovery through collaboration. Featuring the work of multiple Winzeler Lab members and all of our wonderful colleagues in @MalariaTargetID! authors.elsevier.com/sd/article/S14…

Malaria Drug Accelerator #MalDA @MalariaTargetID review their achievements & future directions @ElizabethWinze1 @baragana_b @Kelly_Chibale @LlinasLab @fidocklab @UCSDMedSchool @HarvardChanSPH @DDU_Dundee @ColumbiaMed @theGHDDI @sangerinstitute @MITdeptofBE bit.ly/3qa5E2C

New review out now! Find out who we are and what we do in #malaria drug discovery: sciencedirect.com/science/articl…

Looking to recruit a molecular biologist as a postdoc to our lab to work on Plasmodium falciparum drug resistance and drug modes of action. To join a vibrant team at the Columbia university medical center in New York, working closely with @MedsforMalaria and @MalariaTargetID

Congratulations to MalDA member @fidocklab on this wonderful and well-deserved accomplishment!

Looking forward to @ElizabethWinze1 giving the Craig Lecture this morning at the Alan Magill Sumposium today at #TropMed20. Superb scientist leading the @MalariaTargetID consortium funded by @gatesfoundation

Excited for the start of #MPM2020! Congratulations to all of the presenters, which include multiple Malaria Drug Accelerator members.

Great work by several MalDA members and collaborators showing that a rapamycin analog targets #Plasmodium FKBP35. Out now in @ACSMedChemLett! pubs.acs.org/doi/10.1021/ac…

Congratulations to MalDA member Ian Gilbert on this wonderful accomplishment!

Need some reading material for the weekend? Check out this recent paper identifying serine hydrolases as druggable targets in #Plasmodium. Great work from MalDA affiliate labs and collaborators!

A new drug target for stopping the spread of malaria has been found after a @CellReports study led by @DrBoddey blocked Plasmodium falciparum from completing the ‘transmission stage’ of its lifecycle. In collaboration with @Griffith_Uni wehi.edu.au/news/new-drug-…

For the first time, global efforts are preventing almost 100 million cases of #malaria every year. 🙌 This is great news, but @WHO's report shows that the decline in cases & deaths has slowed significantly. We must accelerate progress to #EndMalaria. gates.ly/35pLhVO

Out now in @CellChemBiol: "Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery." Great work by MalDA team members including @LlinasLab & @WinzelerLabUCSD, spearheaded by @fidocklab's @MurithiJamesM! sciencedirect.com/science/articl…

Check out this @biorxivpreprint article on genome engineering in #malaria parasites from a MALDA member lab! The AT-rich P. falciparum genome is extremely challenging to manipulate, so this is some truly exciting work from Jacquin Niles' group at @MIT! biorxiv.org/content/10.110…

With our latest MalDA meeting coming to an end, we would like to celebrate all of the hardworking #malaria researchers that make this collaboration so successful. Thanks for the insightful discussions and great #science!

Check out this study by MALDA member labs!

In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model stm.sciencemag.org/content/11/521…