Nano Bio Optics Lab (Yoav Shechtman)

249 posts

Nano Bio Optics Lab (Yoav Shechtman)

@ShechtmanLab

We develop microscopy methods to observe life on the nanoscale

Israel Tham gia Aralık 2015

294 Đang theo dõi1K Người theo dõi

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·21 Eki

Gen-AI producing fancy data augmentation for Super-resolution microscopy! Great work @AlonSaguy and team! @HenriquesLab @HeilemannLab

Ricardo Henriques@HenriquesLab

If robots could dream of microtubules, how would they look like? An amazing story by Alon Saguy, @ShechtmanLab and colleagues. Proud we could contribute to it onlinelibrary.wiley.com/doi/10.1002/sm…

English

1.8K

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·17 Tem

@hagenom Great - congrats!

English

Yuval Ebenstein@hagenom·16 Tem

Happy to tell that our our startup, Medical Diagnostics Company, JaxBio Technologies, Secures €2.5 Million Grant from European Innovation Council Accelerator prweb.com/releases/medic…

English

2.2K

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·9 Tem

@BejaLab @EMBO @BiologyTechnion Congratulations!

English

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·9 Tem

@rolls_asya @EMBO Great, congrats!

English

Asya Rolls@rolls_asya·9 Tem

Thank you @EMBO for this great opportunity to be part of this amazing community

EMBO@EMBO

Outstanding scientists elected to EMBO Membership: in EMBO’s 60th anniversary year, 100 new members and 20 associate members join the community embo.org/press-releases…

English

131

8.2K

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·9 Tem

@HenriquesLab @EMBO Awesome, congrats!

English

Ricardo Henriques@HenriquesLab·9 Tem

🔬🎉 Grateful for being elected an @EMBO member. A testament to the hard work and support of the entire lab team over the years 😍. Looking forward to interact even more with the brilliant community and continue to help the next generation of outstanding scientists

EMBO@EMBO

Outstanding scientists elected to EMBO Membership: in EMBO’s 60th anniversary year, 100 new members and 20 associate members join the community embo.org/press-releases…

English

293

15.9K

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·21 Haz

Great work @yevgenin @DanielleSapir et al.!

Yevgeni Nogin@yevgenin

Thrilled to share OM2Seq! We applied #AI methods to #Genomics, improving the speed and accuracy of optical genome mapping for fast diagnostics of diseases. @DanielleSapir, Tahir Detinis Zur, Nir Weinberger, @boknilev, @hagenom, @ShechtmanLab 🔬🚀

English

306

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·8 Haz

We used the Incucyte system by @SartoriusGlobal. All this and more in our latest paper: link.springer.com/article/10.103…. Big thanks and congrats to all co-authors and collaborators: Nadav, @EliasNehme9 Noam, Ilana, Reut, Boris, Paul, @AlaloufOnit , @SartoriusGlobal !

English

285

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·8 Haz

This enables PSF engineering in space-limited microscopy systems, e.g. that fit into incubators. Uses include extended depth-of-field and snapshot 3D spheroid from 2D, using algorithms by @EliasNehme9. Bonus: Obtaining training images is easy with a high-throughput microscope.

English

723

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·8 Haz

PSF engineering typically requires a 4-f system, but this is not always feasible, e.g. due to size constraints. Nadav Opatovski attached a phase mask directly to the objective lens, see beads defocusing here. Tetrapod mask shown here (wait for the end):

English

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·9 May

@Ella_Maru @naturemethods @AlonSaguy @AlaloufOnit @HeilemannLab Thanks! Re simultaneous processes - there will be a complexity-performance tradeoff that would be interesting to check (TBD). Of course if the processes are labeled orthogonally (e.g. different colors) then each one will just be solved separately.

English

Ella Marushchenko@Ella_Maru·14 Nis

@ShechtmanLab @naturemethods @AlonSaguy @AlaloufOnit @HeilemannLab Congratulations on groundbreaking advancement! How does DBlink perform in dense, complex cellular environments with multiple simultaneous dynamic processes?

English

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·27 Tem

🥳 DBlink is now peer reviewed and improved! Online in @naturemethods: rdcu.be/dhUmZ Congrats @AlonSaguy, @AlaloufOnit, @HeilemannLab et al.!

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab

New prepint just out! Live cell single molecule localization microscopy at >3 fps. The information is mostly there - just spread out in space and time :) We use a recurrent neural net (LSTM) + some assumptions to extract it. All details here: biorxiv.org/content/10.110…

English

8.7K

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·8 Tem

More info in the preprint: biorxiv.org/content/10.110………, where we demonstrate the use-case of generating training data for CARE (by @martweig et al.) 3/4

English

311

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·8 Tem

Alon Saguy et al. trained a diffusion model to generate synthetic images of super-resolution microscopy images using data of only a few images from ShareLoc (shareloc.xyz). 2/4

English

621

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·8 Tem

One of these super-resolution microtubule images was captured by a microscope and the other one was generated by a diffusion model. Can you tell which is which? Try more here: clever-microscopy.com/this-microtubu… 1/4

Nano Bio Optics Lab (Yoav Shechtman) tweet media

English

6.4K

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·8 Tem

This is a very ongoing project, with many open questions: what are the performance limits? How much can we really gain beyond the information in the training data? and of course: what would be the best uses of something like this in super-resolution microscopy? 4/4

English

213

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·27 Haz

@christlet Interesting. Do you also get blinking-pairs mistaken for a vertically-elongated PSF (high Z)? I would expect to see a similar number of those.

English

335

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·5 Haz

@AmitZeisel @eLife @_delkind_ @OpenU_Israel Congratulations!

English

118

Amit Zeisel@AmitZeisel·5 Haz

I’m very happy to share that our article “Sex, strain, and lateral differences in brain cytoarchitecture across a large mouse population” is now out in @eLife Congrats to study leader David Elkind(@_delkind_), my collaborator Noam Shental @OpenU_Israel, and all contributors.

English

19.7K

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·5 Haz

@dvir_a @AmitZeisel @eLife @_delkind_ @OpenU_Israel 🤐

QME

Dvir Aran@dvir_a·5 Haz

@AmitZeisel @eLife @_delkind_ @OpenU_Israel @ShechtmanLab please don’t tweet on new publications in the near future. My 8th floor ego won’t be able to bear it :)

Chicago, IL 🇺🇸 English

202

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·2 Haz

@stern_lab @eLife Congrats!!

English

100

Nano Bio Optics Lab (Yoav Shechtman)@ShechtmanLab·29 May

Great work by @yevgenin applying information theory to optical genome mapping, with implications to optimal label design

Yevgeni Nogin@yevgenin

New #preprint! TLDR: Applying #informationtheory on #OpticalGenomeMapping🧬, one can choose pattern-labelling #enzymes giving #10x accuracy! 🤯 biorxiv.org/content/10.110… To illustrate, let’s play a game! ⬇️ (1/4)

English

638

Khám phá

@AlonSaguy @HenriquesLab @HeilemannLab @hagenom @EMBO @BiologyTechnion @rolls_asya @yevgenin