Simone Immler

We had a great end to 2024 publishing: The Zebrafish Sperm Proteome …iencejournals.onlinelibrary.wiley.com/doi/10.1002/pm… We described >5400 sperm proteins generating a great atlas for future work! Spearheaded by PhD student @JaymeCohenBIO with great collaborators at @biouea and @JohnInnesCentre

This is a simple parsimonious model to explain the evolution of lifespan extension by dietary restriction and other forms of stress that suppress fertility. Happy to be part of this exciting study!

🚨Our new paper @SimoneImmler FishPi: a #bioinformatic prediction tool to link #piRNA and #transposable elements Read now in Mobile DNA >> rdcu.be/d7Jub ✅ Covers many species (more to come) ✅ GUI based software #TESky #zebrafish #transposons @biouea 🐟🥧🥧🥧🥧🥟

We had a great end to 2024 publishing: The Zebrafish Sperm Proteome …iencejournals.onlinelibrary.wiley.com/doi/10.1002/pm… We described >5400 sperm proteins generating a great atlas for future work! Spearheaded by PhD student @JaymeCohenBIO with great collaborators at @biouea and @JohnInnesCentre

🚨 Happy to share my latest preprint on #polarbear #transposon activity in response to diverging climates in #Greenland #TEsky 🐻‍❄🌞❄️🧬👩‍💻

🚨Pleased to share our latest preprint on #zebrafish #geneexpression and #transposons in #sperm & #embryos exposed to social stress

I finally caved and am now on bluesky - help me finding you and follow me there @immler.bsky.social and send me starter packs! Thank you!

We have PhD position advertised in evolution of ageing with Tracey Chapman and @SimoneImmler: Please contact me if you have questions about the project or about this PhD programme aries-dtp.ac.uk/studentships/m…

Why is there so much diversity in male seminal fluid proteins? Funded PhD position available with Tracey Chapman @biouea Research team includes @WolfnerLab , @WHaerty , @SimoneImmler and me biodtp.norwichresearchpark.ac.uk/projects/more-… Applications deadline Nov 25

I am also incredibly proud of this preprint: Gum Arabic (Acacia senegal) enhances reproduction and modulates the microbiota-gut-brain axis.... biorxiv.org/content/10.110… Again a massive team effort by @Ko0L_J_ @asdfjohnny @AliceGodden @JaymeCohenBIO et al!

@ItamarHarel Thank you, Itamar!

Very cool!!

Incredibly excited to share our preprint (shorturl.at/JTwuJ) from @SimoneImmler’s Lab 🥳! By harnessing genomics, proteomics, and phenomics, we show that selecting high-quality sperm within an ejaculate could reduce the risk of diseases in future generations 🤯!

I am incredibly proud of this paper in preprint: Within-ejaculate haploid selection reduces disease biomarkers in human sperm lnkd.in/dZwDJHbX It has been long in the making and has been a true team effort! @danielmarcu @JaymeCohenBIO @AliceGodden @GAlavioon et al!

Selection within the ejaculate of men results in genetic changes in key genes involved in neurodevelopment, cell signalling and cell proliferation and that the 'fitter' sperm in an ejaculate exhibit reduced expression of biomarkers for neurodevelopmental disorders and cancers

Germline removal benefits males more than females - led by @martin_i_lind in @AgingCell : onlinelibrary.wiley.com/doi/full/10.11… (see earlier bioRxiv link below). Stress resistance improved in both sexes. Remarkable congruence with killifish work pubmed.ncbi.nlm.nih.gov/38750187/ @ItamarHarel

Reduced insulin/IGF-1 signalling upregulates two anti-viral immune pathways, decreases viral load and increases survival under viral infection in C. elegans by @E_Duxbury et al

I am very happy to announce the recent publication of a beautiful theory paper with @mscott0106 and Karl Mackintosh (not on X) on the interactions between mating system evolution and haploid gametic selection in @PLOSGenetics doi.org/10.1371/journa…

Merger of NYRA @YoungAndrology with @EAAndrology is highlighted in this society news article published in Andrology 🤩 onlinelibrary.wiley.com/share/author/A… @AndrologyASA