Jim Smithy
795 posts

Jim Smithy
@jsmithymd
melanoma oncologist @mskcancercenter I clinical trials, cellular therapy & translational immunotherapy research | n.b.: personal account
New York, NY Tham gia Ağustos 2010
908 Đang theo dõi971 Người theo dõi
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Among patients with immune checkpoint inhibitor–related cutaneous adverse events, dupilumab therapy was associated with lower 5-year mortality compared to no dupilumab or systemic corticosteroids. ja.ma/4167rLa

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Herald Square is the most underrated neighborhood
I don't get why people hate it
- Most convenient area in NYC (B, D, F, M, N, Q, R, 1, 2, 3 & PATH trains) – you can get anywhere in the city within 20 min
- Excellent food (Keen's, Ai Fiori, Noksu, Joo Ok, Rezdora)
- A great meeting spot - probably the geographic center of Manhattan
- Ktown is awesome
- Gyms EVERYWHERE (Equinox, Lifetime, Crunch, Planet Fitness, NYSC, Orange Theory)
- Great coffee all around - possibly the most dense cluster of cafes in Manhattan
- All the grocery stores and shopping you would ever need

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I wrote about the ambiguity in prognosis of a stage IV cancer diagnosis nowadays and the bravery our patients exhibit when they navigate that ambiguity every day. @NEJM
nejm.org/doi/10.1056/NE…
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Ellen was diagnosed with a rare and hard to treat #ovariancancer. Everything changed when she enrolled in a clinical trial led by Dr. Rachel Grisham, based on a lab discovery years ago by @DSolit.
Watch more #SavedbyScience stories on YouTube: bit.ly/3ZLODjv
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Thrilled to have matched into oncology fellowship at @MSKCancerCenter ! (w/ my amazing colleagues and friends @MGHMedicine PSP). I’m truly grateful and excited for this next chapter at @MSK_DeptOfMed, an institution that has served so many I love. Can’t wait to get started 🤍

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that’s a wrap on melanoma bridge! three days tackling the most pressing questions in the field with an inspiring roster of speakers… thank you @PAscierto & colleagues for organizing


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@Chrystal_Paulos @PAscierto congratulations and fantastic talk!! excited to see what’s next for Th17 adoptive cell therapy
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So grateful to receive the Bridge Award 2025 at Melanoma Bridge in Napoli — truly my favorite meeting. Thank you Dr. Paolo Ascierto @PAscierto and the organizers for championing T-cell innovation and this amazing family/community.

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More than a year after receiving a type of immunotherapy called tumor-infiltrating lymphocyte (#TIL) therapy, Pattie is doing well and has almost no signs of metastatic #melanoma
Learn more from @jsmithymd, a melanoma medical oncologist and cellular therapist at MSK and expert in #TILtherapy.
bit.ly/3X9yBP0

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New Yorkers move fast, so should our trains.
Starting on October 6th, Super Express service launches on the @MetroNorth Hudson Line, months ahead of schedule, with trips under 90 minutes.
This is how we build a stronger, faster, more connected New York.

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Published by @OncNewsCentral | I had a great conversation with Dr @jsmithymd & Dr Michael Postow on the latest in #Melanoma #Immunotherapy & #MolecularlyTargetedTherapy - Navigating Options
@MoffittNews
@MSKCancerCenter
oncologynewscentral.com/video/melanoma…

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Scientists conducting medical research are facing an existential crisis: Layoffs and budget cuts pushed by President Trump that, they say, jeopardize finding a cure for cancer.
Ted Koppel talks with cancer patients taking part in clinical trials for treatments and vaccines, whose own contributions to finding a cure are imperiled.
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🎥@jsmithymd of @MSKCancerCenter highlights the need for careful post-discharge monitoring of patients with melanoma treated with lifileucel due to risks of cytopenias. Tailored follow-up is key:
🔗 ow.ly/qver50WgfE3
@ASCO #ASCO25 #Melsm #Skcsm #ImmunoOnc
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Wonderful to see Irish fellows on the podium @ASCO discussing novel preoperative approaches @RonanAndrewMcL1 @LochrinSarah




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Underway now in the #melanoma rapid oral abstract session at #ASCO25: Sarah E. Lochrin, MBBCh (@LochrinSarah) from @MSKCancerCenter shares interim results from the C-IT Neo trial on single-dose neoadjuvant ipilimumab + nivolumab in resectable melanoma, with CD8+ PET imaging.
➡️ 59% major pathologic response after one dose
➡️ Grade ≥3 treatment-related AEs in just 9%
➡️ CD8+ PET tracer uptake correlated with IHC, but not predictive of response
#Immunotherapy #Neoadjuvant @ASCO #MoffittASCO25



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Congratulations to Kathryn Arbour @KCArbourMD and colleagues showing activity of BMS-986504 in MTAP-deleted solid tumors, including lung and pancreas cancer. @MSKCancerCenter

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