置顶推文
Officially out in Nucleic Acids Research @NAR_Open: Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release academic.oup.com/nar/article/do… 1/9
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Matjaž Barborič
641 posts
Matjaž Barborič
@BarboricLab
Group leader at the Faculty of Medicine @helsinkiuni. Barborič lab studies basic principles of gene regulation for therapies of the future.
Helsinki, Finland 加入时间 Şubat 2019
262 关注196 粉丝
@jdamijan Kompas finančnih vlagateljev je profit. Švicarska energetska pot predstavlja jasno alternativo, tudi za Slovenijo.
Slovenščina
Konec "sončne in vetrne" ere (ki je ugasnila z ugasnitvijo subvencij). Finančni vlagatelji se množično umikajo iz sonca in vetra in se fokusirajo na jedrsko energijo (potrojitev kapacitet) kot edinega izdatnega, stabilnega in poceni nizkoogljičnega vira energije.
Z jedrsko energijo ne potrebuješ enormnih vlaganj v omrežje in baterije ter v pravljico o zelenem vodiku. Energetski prehod iz plina in premoga (razogljičenje) je zato za polovico cenejši od sončne & vetrne pravljice.
Financial Times@FT
Fourteen institutions, including Citi, Morgan Stanley and Goldman Sachs, will pledge to support a goal to triple the world's nuclear energy capacity by 2050. on.ft.com/3XyfoGB
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A postdoc position is open in my lab @helsinkiuni
@LifeSciHelsinki @HelsinkiUniMed Are you interested in RNA Pol II @generegulation, transcriptional cyclin-dependent kinases, and how these could be targeted in cancer? Apply by September 16th. Please RT jobs.helsinki.fi/job/Helsinki-P…
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Doctoral researcher position is open in my lab @helsinkiuni @LifeSciHelsinki @HelsinkiUniMed
Are you interested in RNA Pol II @generegulation, transcriptional cyclin-dependent kinases, and how these could be targeted in cancer? Apply by September 16th: jobs.helsinki.fi/job/Helsinki-D…
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Matjaž Barborič 已转推
Our review about CDK11 is out in @TrendsCellBio now.
We discuss evolution of CDK11 - SF3B1 axis and its role in pre-mRNA splicing. We also summarize how CDK11 and its inhibition affect transcription and cell cycle progression.
Free access here: authors.elsevier.com/a/1jjxs3QxxSux…
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Matjaž Barborič 已转推
Still digesting the landmark #Draghireport, but great to see the emphasis on R&I. Very happy with proposal to double support to ground-breaking fundamental research via the European Research Council! And the stance on preserving the ERC's independence.
commission.europa.eu/topics/strengt…
Kurt Deketelaere@LERU_SG
Mario Draghi on the @ERC_Research. Perfect summary 👏👏 ! @LERUnews
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@briebriejoy I thought the ending of your post would say "... In this sense, he is a traditional Democrat."
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Zero surprises for anyone who didn’t selectively forget their lefty power analysis when Kamala showed up with some nifty memes.
Money begets outcomes. And power isn’t handed to those who pose any threat to the status quo.
Ken Klippenstein@kenklippenstein
Kamala Harris’ campaign website just posted a policy page. Here’s what it says about Israel and Gaza: “Harris will always stand up for Israel’s right to defend itself and she will always ensure Israel has the ability to defend itself. She and President Biden are working to end the war in Gaza, such that Israel is secure, the hostages are released, the suffering in Gaza ends, and the Palestinian people can realize their right to dignity, security, freedom, and self-determination. She and President Biden are working around the clock to get a hostage deal and a ceasefire deal done.”
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Are you a BSc/MSc student of life sciences at the @helsinkiuni @HiLIFE_helsinki @HelsinkiUniMed @LifeSciHelsinki dreaming of doing research on @generegulation and #Cancer in my lab? Apply for the HiLIFE 4-month Research Trainee Scholarships here: studies.helsinki.fi/instructions/a…
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Research Council of Finland has another call for inviting researchers from Ukraine to Finland. Will @SuomenAkatemia stand by its academic and moral principles and commit to open a call for Palestinian researchers fleeing the genocide and destruction in #Gaza and the #WestBank?
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Take a pause and listen what the pediatric intensive care and humanitarian physician @Tanyaalih of @MSF had to say at the first-ever panel on Palestinian human rights at the @DemConvention in Chicago on the devastating suffering she witnessed in #Gaza hospitals #FreePalestine
Monica Marks@MonicaLMarks
Extraordinary testimony from pediatric intensive care Dr. Tanya Haj-Hassan (@Tanyaalih), who spoke about suffering at the hospital where she worked in Gaza. In a historic first, @uncommittedmvmt held this panel on Palestinian rights at the DNC yesterday:
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Matjaž Barborič 已转推
"Povprečne zimske temperature na Svalbardu so se v zadnjih 30 letih dvignile za 10 stopinj Celzija," mi je povedal Kim Holmen iz Norveškega polarnega inštituta. Dva dni zapored je termometer presegel 20 stopinj - na skrajnem severu.Goreti bi morali vsi alarmi. There. Will. Be. B.
Slovenščina
A comprehensive review by @dorsolab on mechanisms regulating HIV-1 proviral transcription and strategies of exploiting the knowledge for reactivating and eliminating the latent reservoir. Congrats!
Ivan D’Orso@dorsolab
My review about “The HIV-1 transcriptional program” for the @JMolBiol special issue on transcription elongation is now out: doi.org/10.1016/j.jmb.…. I provide a 4 decades historical recount from mechanistic insights to implications for viral latency and cure. Thanks @NIAID!
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Our paper highlighting the counterintuitive importance of negative regulation of transcription elongation to facilitate full gene activation during cell fate decisions is out: nature.com/articles/s4146…. Congrats @whoishegotyou and @challa_ashwini and the collab with the @KrausLab
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@ABugai Money talks! We should not expect any morality by the weapons industry. As George W Bush has said back in 2002, war is good for economy.
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@BarboricLab right, ru deliberatively targets children hospital. There is no doubpt about the genocidal intent of the russians.
how EU/US-made parts are make into those missiles or how ru never runs out of cash to buy those are amoung more actual questions.
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thanks to the policies of western leaders Ukraine could not hit military airfields in russia which used for terror attacks like today...
Jay in Kyiv@JayinKyiv
Video slow motion. Two intentional, precise Russian missile strikes on a busy Kyiv children's hospital.
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@mpgpresident And with Palestinians? Is there no solidarity with the population being eradicated by your friend's genocidal actions?
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Neues Interview: Deutsche Wissenschaftsorganisationen solidarisieren sich mit Israel
deutschlandfunk.de/deutsche-wisse…
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Matjaž Barborič 已转推
Here’s a simple fact: If politicians stand with working families, working families will stand with you.
As it turns out, lowering the retirement age & raising the minimum wage are very popular.
Congratulations to the French Left for taking on right-wing extremism and winning.
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Matjaž Barborič 已转推
Julian Assange - "The world is not sliding, but galloping into a new transnational dystopia. The internet, our greatest tool of emancipation, has been transformed into the most dangerous facilitator of totalitarianism we have ever seen. The internet is a threat to human civilization." (2012)
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Matjaž Barborič 已转推
“The US intellectual, who has died at the age of 95, exposed the hidden workings of power.”
newstatesman.com/ideas/2024/06/…
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@NetPharMed @SuomenAkatemia @McManus_Lab @CarolineFriedel @science_yall @JuhaKlefstrom Thanks, Jing!
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@BarboricLab @SuomenAkatemia @McManus_Lab @CarolineFriedel @science_yall @JuhaKlefstrom Contratulations!
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Thanks @SuomenAkatemia for the vote of confidence! Now it's on us to reveal new routes of gene control by transcriptional CDKs and to exploit this against cancer. Thanks to my team and collabs @McManus_Lab AnniinaVihervaa @CarolineFriedel @science_yall @JuhaKlefstrom @NetPharMed
University of Helsinki@helsinkiuni
Research Council of Finland has granted academy funding for 66 Academy Projects as well as for 42 Research Fellows. Congratulations to all! 🤩👏 #WeAreHelsinkiUni @SuomenAkatemia 👉 aka.fi/en/about-us/wh…
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