The ProMOTE Study

Excited to publish our #FirstInMan phase 1 study using IR800-IAB2M (near infrared #PSMA minibody) dosing and toxicity in n=23 men undergoing #RARP +/- #ePLND #ProstateCancer #PrecisionSurgery @NDSurgicalSci @LambAlastair @LabBryant link.springer.com/article/10.100…

If you're not here come now!! eUro2, 1715-1800 @gu_onc "From Studio to Stage!!" With @declangmurphy & @RenuEapen #EAU26 @Uroweb

Pleased to publish #CostEffectiveness data #LATPvsTRUS in @EurUrolFocus THM: •average cost TRUS=£917; LATP=£1062 (∵ device cost/takes longer) •#LATP not cost-effective (QALY) But... •only 4m f/u so doesnt account for ⬆️ PCa diag #TRANSLATE_Trial eu-focus.europeanurology.com/article/S2405-…

Fascinating on UK #PCaScreening •Men 50-69 yo ❌️ (n=8.2M) •Familial risk ❌️ (1M) •Black ethnicity ❌️ (0.37M) •BRCA mutated ✅️ (21k) So...the screening gates opened for 1st time! 💥 Thoughtful from #NSC (but suspect many will be disappointed) bbc.co.uk/news/live/clyk…

Final case of the day (and of #ERUS25 @GuysUrology) with @bernardorocco73 #RARP modified anterior approach with @Medtronic #HUGO. 65 yo gent looking forward to retirement in Caribbean! •GG3 8mm Rt ant, GG2 4mm Lt post •T2N0M0 •ElIPSE trial - rndmed to no LND @BAUSurology

Final morning of #ERUS25, the sun is shining in anticipation of the first case of the day with @agalfano at @GuysUrology Plan is for a @Medtronic #HUGO #rsRARP Delightful portuguese gent with: •GG2 6mm Rt anterior •Borderline cT3a •MUL 15mm And fully aware of #LiveSurgery

First live case of #ERUS25 ready to rock @GuysUrology. @prokarurol in the #HUGO hot-seat. WHO time-out done. Patient from @GibraltarGov #StBernardsHospital & fully on board with #LiveSurgery concept #CuttingEdgeSurgery #EveryDaysALearningDay

Co-Chief Investigator @LabBryant outlines #TRANSLATE_TRIAL journey during @NDSurgicalSci #SurgicalGrandRounds this morning. @OCTRUctu @SITU_Oxford #SGR #Oxford_Urology

V grateful to @declangmurphy for his excellent, provocative & thoughtful "discussant" response to #TRANSLATE_Trial read-out by @LabBryant @LambAlastair @NDSurgicalSci @sashi_kommu @DrBenEddy @HideYamaUrol @Mattpingchao Watch it again in full here ⬇️ youtu.be/O4-wKmhza6Y

Trial CI @LabBryant delighted to read out #TRANSLATE_Trial results during #GameChanger session @Uroweb #EAU25 Thank you to all our investigators, recruiting sites, funders @NIHRresearch and, most importantly, our 1126 pts! thelancet.com/journals/lanon… Trial visual abstract below ⬇️

Breaking news pod - TRANSLATE trial just presented at #EAU25 with co-publication @TheLancetOncol @LabBryant @LambAlastair @TranslateTrial. Discussant @declangmurphy Deep dive on GU Cast just released youtu.be/QdWlFy2zrHU?si…

Excited to announce #TRANSLATE_Trial outcomes will read out at 10am Sun 23rd March in eURO Auditorium 1 #EAU25, Madrid Synchronous embargoed publication in @TheLancetOncol #LATPvsTRUS - we'll finally give you the answer Hope to see you there! @GUCast @LabBryant @LambAlastair

@TranslateTrial results @Uroweb EAU Madrid, 10am Sunday 23/3/25, Green Area eURO Auditorium 1. #LATP v #TRUS prostate biopsy, n=1126; 1ry outcome GGG>=2 cancer detection, 2ry = infection, other complications, cost-effectiveness; @LambAlastair @LabBryant @NDSurgicalSci @OCTRUctu

Last list on fellowship with @LambAlastair at @OUHospitals NHS Trust . HUGE thank you to Prof. Alastair Lamb, privilege to learn from you. TY for the invaluable masterclass in robot assisted radical prostatectomy. GRATITUDE to excellent scrub team members too! #SurgicalMentor

Today we publish first installment of #PROMOTE_Trial in @EANM_NucMed #EJNMMI journal n=23; 48% pT3b; 43% pN1 Node +ve fluoro n=8 Margin +ve fluoro n=10 Optimal dose of IR800-IAB2M PSMA minibody: 5mg iv 10d pre-RARP @PromoteStudy funded by @CRUKresearch link.springer.com/article/10.100…

How to convert #RARP & #ProstateBx specimens into #CuttingEdge translational science? State-of-the-Art Tips&Tricks video on #SpatialTranscriptomics analysis w #VisiumV2 @OxPCaBiol @NDSurgicalSci Presented by @thineskrishna @ #AUA24 #OrganscaleNodes youtu.be/_jqTHaKSfxo?si…

@Freddie_Hamdy drops the 🎤 @Prostate_Forum on thought expmt #FocalTherapy as "4th arm" in #ProtecT_Trial Opponent: "well never be able to do RCT of Focal vs RP" FCH: "Here's @PART_Trial, our RCT of partial vs radical Tx, international support & recruiting nicely" !! #AUA24

Please come see our poster showing how we use #SpatialTranscriptomics to deduce clonal metastatic relationships in high-risk surgically treated #prostatecancer #LethalClone #Space_Study @QuantumBiobank @Wien_Yin & @Sandy_Figiel will answer all your qus! @OxfordCancer #OxSymp24

Inviting appls to #Oxford_Urology pelvic uro-onc fellowship for Aug '24. Approx cases pa 180 RARPs/40 RARCs/600 Bx (TRUS&LATP) @IntuitiveSurg UK HQ in Oxford Key role in 4 RCTs: -@PromoteStudy -@PART_Trial -@AtlantaIp2 -FINESSE Close: 15/12 Intv: 22/12 nhsjobs.com/job/UK/Oxfords…

A great day of golf ⛳️ @ClubHuntercombe #CaptainsDay in support of @UCAREoxford w particular emphasis on fundraising for @NDSurgicalSci research nurse. Much needed to keep running novel trials/lab research to help our patients And my awesome sister won Ladies Longest Drive!!🏆🍾