
Van Rechem Lab
629 posts

Van Rechem Lab
@VanRechemLab
Interested in epigenetics and more particularly in chromatin modifiers in translation (what?!? Yes!) and in cell cycle/replication




Our team had a great time at the 2025 @AACR Annual Meeting! Congrats to Georgia Pinner for her impactful poster presentation. It was also wonderful hearing from @XiHuang18 and reconnecting with @FilbinMariella and @VanRechemLab after their sessions. bit.ly/3re2yOt





A career highlight for me is to see a former trainee take an international stage @AACR #AACR25 to discuss her lab discoveries. Great talk @VanRechemLab. She discussed #oncohistones, #epigenetic regulation & impact on #CellCycle to #Therapeutics. @CeiFccc @FoxChaseCancer


Today, we report that APOBEC3B targets unprotected single-stranded DNA at replication forks upon ATR inhibition, triggering a reaction cascade involving UNG2 and APE1 that leads to fork collapse and hyperactivation of PARP1, causing replication catastrophe.science.org/doi/10.1126/sc…

THE COUNTDOWN BEGINS 🌟 EpiCypher 2025 Registration Opens April 1st! Join top experts in chromatin & epigenetics at #Epi2025! The conference will take place November 2-7, 2025, at Grand Fiesta Americana Coral Beach in Cancún, Mexico! Learn more here: epicypher.com/epicypher-2025…

It can be hard to say no to service requests in academia. We sought advice on how to ensure researchers don’t get stuck doing unpaid labour go.nature.com/4bUX6WN






Papers alert! The lab ended 2024 well with two published stories in Dec. 1- Anastasia @5_hmC and collaborators found that DMG have altered DNA replication and timing and are in a state of replication stress opening new potential therapeutic options. genomebiology.biomedcentral.com/articles/10.11…

Papers alert! The lab ended 2024 well with two published stories in Dec. 1- Anastasia @5_hmC and collaborators found that DMG have altered DNA replication and timing and are in a state of replication stress opening new potential therapeutic options. genomebiology.biomedcentral.com/articles/10.11…









