SunLab

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SunLab

SunLab

@JiSunLab

The Sun Lab | Dept. of Biological Science @ National University of Singapore

انضم Eylül 2019
307 يتبع652 المتابعون
SunLab أُعيد تغريده
ZhengLab
ZhengLab@LabZheng·
Excited to share our lab's latest discovery today in @Nature: "orthosteric molecular glue” (OMG) inhibitors - a new drug design strategy that achieves substrate-dependent potency, i.e., substrate selectivity, with conventional orthosteric inhibitors. rdcu.be/e3waV
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SunLab
SunLab@JiSunLab·
My lab #NUS is located at the place near the arrow. My daily walk to the lab feels like stepping into the applewood Wardrobe in Narnia.
SunLab tweet media
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SunLab
SunLab@JiSunLab·
Happy to share our new publication on KCNQ1. In this work, we reveal a cool molecular mechanism that modulates the tissue-specific function of KCNQ1 through its beta subunits, KCNE1/3, which provides different voltage and PIP2 (GPCR) sensitivity for gating nature.com/articles/s4142…
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Lindsay Schwarz 🌧
Lindsay Schwarz 🌧@lindsayschwarz·
fitting that my PECASE certificate finally arrived many months late and looking worse for wear (much like me these days😂😭). Still grateful to the Biden admin. for recognizing the importance of junior investigators in science❤️
Lindsay Schwarz 🌧 tweet media
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Yi-Wei Chang
Yi-Wei Chang@yiweichang·
...and big thanks to @janetiwasa for making this amazing video to illustrate the strand-sliding mechanism!
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Yi-Wei Chang
Yi-Wei Chang@yiweichang·
Excited to share our new @ScienceMagazine paper! Led by postdocs Ruchao Peng and Xin Xu, we used cryo-EM/ET to reveal the influenza ribonucleoprotein complex structure and its strand-sliding mechanism for RNA synthesis, paving the way for new antivirals. science.org/doi/10.1126/sc…
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SunLab أُعيد تغريده
St. Jude Research
St. Jude Research@StJudeResearch·
Our researchers, in collaboration with the Medical College of Wisconsin, have discovered how chemokines and G protein-coupled receptors (GPCRs) selectively bind to control how cells move. ow.ly/77Yl50VGpKe
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SunLab أُعيد تغريده
nature
nature@Nature·
Nature research paper: VDAC2 loss elicits tumour destruction and inflammation for cancer therapy go.nature.com/41AWsZX
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Rui Zhang
Rui Zhang@RuiZhangWUSTL·
1/n) Best way to start 2025! Thrilled to share our Nature paper about the structures of axonemal components from sperm flagella and from epithelial cilia of the oviduct and brain ventricles. Great collaboration with @TzviyaZBM and @alanbrownhms nature.com/articles/s4158…
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اكتشف

@Nature @lindsayschwarz @PNASNews @yiweichang @janetiwasa @ScienceMagazine @abu_remaileh @JunminPengLab