Nathan Lord

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Nathan Lord

Nathan Lord

@LordLab_Pitt

Asst. Professor in @compbiopitt. Our lab is interested in cell fate decisions in embryos, noisy signaling and optogenetics.

انضم Eylül 2021
376 يتبع503 المتابعون
Nathan Lord أُعيد تغريده
Hattie Chung
Hattie Chung@hattaca·
Our lab at @YaleMed seeks #postdocs with in vivo expertise to pioneer research at the intersection of tissue remodeling & aging. Work with us to uncover immunological & vascular drivers of ovarian aging, applying single-cell, spatial omics, and ML!
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Thomas Norman
Thomas Norman@thenormanlab·
Our paper is now out in final form at Nature Genetics! For those who missed the preprint, we used large-scale Perturb-seq targeting transcription factors to push primary fibroblasts into diverse transcriptional states, including those observed in cell atlas studies.
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Hattie Chung
Hattie Chung@hattaca·
Excited to share that we've received an @NIH R35 MIRA! This grant will support our work building tools to study how cell states change over space and time in disease. Grateful to our community, and especially the wonderful team I get to work with.
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Matt Durrant
Matt Durrant@mgdurrant·
Posting our preprint showing bridge recombinase editing in human cells again here. Please reach out if you have questions! biorxiv.org/content/10.110…
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Nathan Lord
Nathan Lord@LordLab_Pitt·
We're very excited to have the final version of our paper up in @Dev_journal. We describe a new system for spatial control of Nodal signaling in live embryos. Thanks to Development for a helpful and constructive review process! Please reach out if you'd like to try our tools!
Development@Dev_journal

Optogenetic control of Nodal signaling patterns Read this Techniques & Resources Article by Harold McNamara, Alex schier, Adam Cohen, Nathan Lord and colleagues: journals.biologists.com/dev/article/15… 🎥Direct visualization of photopatterning of live zebrafish embryos

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jared toettcher
jared toettcher@toettch·
Read below for the latest from Emily Ho in my lab on in vivo receptor tyrosine kinase biosensors. This has been a *dream* project, seeing endogenous RTK activity in live embryos for the first time. Surprise: they don't always match those of downstream signaling pathways!
Emily Kolenbrander Ho@emkolen

Have you ever wanted to *see* receptor activity in embryos? If so, our new preprint is for you! In it, we showcase a new live-cell biosensor for visualizing receptor tyrosine kinase activity in living embryos – pYtags! biorxiv.org/content/10.110…

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Jue Wang
Jue Wang@jueseph·
My team at Deepmind (protein design) is hiring an experimentalist with enzyme expertise. Please RT and/or apply! I'm happy to answer any questions as well. boards.greenhouse.io/deepmind/jobs/…
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Nathan Lord
Nathan Lord@LordLab_Pitt·
Get in on the ground floor! Working with @h4rrymcnamara was a highlight of my scientific career. He is brilliant, creative, and a joy to work with. His lab is going to do awesome things. Definitely seek him out if you're looking to get into developmental biology for PhD/postdoc.
Harry McNamara@h4rrymcnamara

a personal update: in January, I'm moving to Yale to join @MCDB_Yale and to open my lab in the @WuTsaiYale Institute! We will investigate multicellular self-organization using synbio tools to read and write developmental signals in stem cell models. syndevbio.org

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KichevaLab
KichevaLab@KichevaLab·
Our paper “Dynamics of morphogen source formation in a growing tissue” with first authors R. Ho and K. Kishi is published in @PLOSCompBiol 🎉 We show that the floor plate of the vertebrate neural tube forms in two phases: rapid specification followed by growth. 🧵1/7
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Amjad Askary
Amjad Askary@AskaryLab·
What if you could find out the history of signaling activity in each cell with a single round of imaging? Wouldn't that be incredible? Well, we thought so too. And that's what we set out to achieve with INSCRIBE in our new preprint. Let’s dive in! 🚀🔬 biorxiv.org/content/10.110…
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jared toettcher
jared toettcher@toettch·
Working on this paper with @h4rrymcnamara was just an absolute pleasure, one of the highlights of PI life so far. Even better: he'll be starting his own laboratory in just a few months at Yale - so stay tuned for more exciting work from the McNamara group!
Harry McNamara@h4rrymcnamara

Our study decoding gastruloid symmetry breaking is now live @NatureCellBio! rdcu.be/dVMLG Thank you to the NCB edititorial team and to our reviewers for a constructive review process which helped improve our study. A thread on updates (1/n):

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اكتشف

@jishnu1729 @poholeklab @YaleMed @thenormanlab @hattaca @NIH @YaleCardiology @YaleCVRC