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Thrilled to share that I have joined @AnthropicAI as a life science researcher! I am confident that Claude will do amazing things to accelerate biology. Big things ahead!
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Matt Durrant
1.4K posts
Matt Durrant
@mgdurrant
Life Science Researcher @AnthropicAI. Share feedback on Claude for biology: https://t.co/Rw2bRsK87c
🇺🇸 Katılım Kasım 2017
669 Takip Edilen5.1K Takipçiler
Matt Durrant retweetledi
With the help of Claude Mythos Preview, the Firefox team fixed more security bugs in April than in the past 15 months combined.
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"We anticipate that bridge recombinases, together with advances in predictive bRNA design and bacterial delivery systems, will form a foundation for “synthetic microbiomics”, the systematic, programmable orchestration of gene flow within complex microbial ecosystems."
Brady Cress@bradyfcress
Our lab is proud to present our latest work harnessing Bridge Recombinase for genome-scale editing in diverse bacteria, microbiome editing, and programmable horizontal gene transfer.
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One of the many amazing parts of this paper that you might have missed at first glance!
Brady Cress@bradyfcress
We then leveraged TRADE editing to "capture" entire pathways in vivo and move them between species without ever needing to extract their DNA--just molecular biology accomplished fully within the microbes. This allowed us to move functions across phyla.
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Pioneering work from the @bradyfcress lab using bridge recombinases to perform programmable genomic rearrangements in diverse species (multiple phyla). Congrats to @jayman14661, @swartz_sophi, Agnès Oromí-Bosch, and team!
Brady Cress@bradyfcress
Our lab is proud to present our latest work harnessing Bridge Recombinase for genome-scale editing in diverse bacteria, microbiome editing, and programmable horizontal gene transfer.
Català
Matt Durrant retweetledi
Matt Durrant retweetledi
Bridge RNA stuff keeps floating across my timeline with more and more insanely impressive results.
Brady Cress@bradyfcress
We then leveraged TRADE editing to "capture" entire pathways in vivo and move them between species without ever needing to extract their DNA--just molecular biology accomplished fully within the microbes. This allowed us to move functions across phyla.
English
Matt Durrant retweetledi
Our lab is proud to present our latest work harnessing Bridge Recombinase for genome-scale editing in diverse bacteria, microbiome editing, and programmable horizontal gene transfer.
bioRxiv Synthetic Biology@bioRxiv_synbio
Bridge recombinase enables versatile rewriting of bacterial genomes biorxiv.org/content/10.648… #biorxiv_synbio
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Matt Durrant retweetledi
A beautiful story on the origins of CRISPR -- congrats to @PeterHYoon @kenjmloi and team!
Cool to see the Evo 2 likelihoods being useful for identifying a tricky repeat region.
biorxiv.org/content/10.648…
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An incredible new discovery from the @DoudnaJennifer lab! A mechanistically distinct RNA-guided system with enormous evolutionary and biotechnological implications. Congratulations to @kenjmloi, @PeterHYoon, and the team!
Kenneth Loi@kenjmloi
Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR. We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets. Thread + link below.
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Matt Durrant retweetledi
Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR.
We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets.
Thread + link below.
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Matt Durrant retweetledi
I'm finding Opus 4.7 way more capable at managing, debugging, and executing long-running pipelines. This is the first model I trust to not only write the code but actually run it on all my samples!
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Matt Durrant retweetledi
We're launching the Anthropic STEM Fellows Program.
AI will accelerate progress in science and engineering. We're looking for experts across these fields to work alongside our research teams on specific projects over a few months.
Learn more and apply: job-boards.greenhouse.io/anthropic/jobs…
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Français
I am super excited to share that I am joining @CarnegieMellon as a tenure-track Assistant Professor in Biomedical Engineering @cmu_bme 🎉
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Matt Durrant retweetledi
🧵 My tips for getting the best results out of Claude Design! I’m on the verticals team at Anthropic which means I serve 7 different products. Claude Design makes it possible!
1. Set up your design system and your core screens. An hour of setup and refinement here is worth it
Claude@claudeai
Introducing Claude Design by Anthropic Labs: make prototypes, slides, and one-pagers by talking to Claude. Powered by Claude Opus 4.7, our most capable vision model. Available in research preview on the Pro, Max, Team, and Enterprise plans, rolling out throughout the day.
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Matt Durrant retweetledi
A lot of bugs that folks may have hit yesterday when first trying Opus 4.7 are now fixed. Thanks for bearing with us🙏
Ethan Mollick@emollick
I'll give Anthropic credit for moving quickly. Opus 4.7 Adaptive Thinking now triggers thinking much more often, including for the tasks it failed at yesterday. That also means it is doing a lot more web search. So far, a large improvement in output quality on non-coding tasks.
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An amazing way to take all your project materials and immediately convert them into a beautiful presentation, I’ve loved Claude Design since the first time I used it.
Claude@claudeai
Introducing Claude Design by Anthropic Labs: make prototypes, slides, and one-pagers by talking to Claude. Powered by Claude Opus 4.7, our most capable vision model. Available in research preview on the Pro, Max, Team, and Enterprise plans, rolling out throughout the day.
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Matt Durrant retweetledi
Introducing Claude Design by Anthropic Labs: make prototypes, slides, and one-pagers by talking to Claude.
Powered by Claude Opus 4.7, our most capable vision model. Available in research preview on the Pro, Max, Team, and Enterprise plans, rolling out throughout the day.
English
Matt Durrant retweetledi
Agents for computational biology are advancing rapidly, but evals are lagging. Current benchmarks can be overly prescriptive. Full analysis vignettes are hard to verify. We introduce CompBioBench: 100 diverse, challenging, verifiable tasks + benchmark general-purpose agents. 1/9
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Matt Durrant retweetledi
@mgdurrant noticeable improvement, still needs some wrangling to get it started in the right direction, but much less micromanaging. Mostly the increased effort and thinking depth is really appreciated, for most tasks quality >> speed
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Feel free to throw your hardest structural biology problems at Opus 4.7, and please share feedback so we can keep improving!
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