KidneyGeneticsGroup

The Ong Lab is very pleased to share this exciting new research with you all...

Congratulations Rebecca! Well done!

Exciting and demanding @goKDIGO meeting to provide guidance for #adpkd. Great great team!! Amazing team-work, especially the chairs #torres and #devuyst!! Huge thanks to @goKDIGO staff!! Special mention to smart @Reem_A_Mustafa

🔥New paper highlights importance of genetic testing in CKD pts when etiology is not certain Presentation non-specific: Non-proteinuria CKD, HTN, no gout, +FH, Bx mostly shows IFTA How many such patients have 🫵 seen in clinic⁉️

We identified 41 pedigrees with the UMOD variant across regional centres and national databases. This study provides evidence for a pathogenic ancestral variant prevalent in the British population that is responsible for kidney failure and chronic kidney disease.

Delighted to share our recent publication. A founder UMOD variant is a common cause of hereditary nephropathy in the British population. Thank you to all who helped with this work! @mkvalluru jmg.bmj.com/content/early/…

Congratulations Dr Brooks on completing your PhD! Very well deserved and you will be sorely missed. Hope your head isn't too sore this morning!

The 2nd project funded as part of our partnership with @Kidney_Research is that of Professor Albert Ong, who is on a mission to better understand PKD cyst formation - Potentially a major step towards finding a cure for ADPKD! Read more 👉 bit.ly/ADPKDcsts @Ong_Lab

Back from fabulous @FASEBorg #PKD22 mtg & finally had time to gather my thoughts. What's🔥🔥🔥in PKD? Here are the headlines👇 🧵

My first publication with @Ong_Lab, describing our experience with using everolimus to treat TS-associated AMLs over 5 years. academic.oup.com/ckj/article/15…

Can ketogenic dietary interventions slow disease progression in ADPKD: what we know & what we don’t 👉we should be cautious in recommending KDI or ketone supplementation despite encouraging preclinical findings 📸Dietary modifications in PKD rodent models bit.ly/3rJLmRg

2022 winners - Alessandra Boletta, Italy 🇮🇹 - Alvert C. M. Ong, UK🇬🇧 Congratulations! 👏👏 @PKDFoundation #ISNWCN

@AlanYuNeph @Boletta_Lab Thank you!

Brava bravo!👏👏👏 @Boletta_Lab @Ong_Lab

Don't forget to register for our next 'Driving discoveries' virtual event next week! Hear from Dr Maria Fragiadaki, who will present her work unlocking the ADPKD mechanism to provide hope of new medicines for people affected with ADPKD. Register now 👉 bit.ly/3qNF8P2

@ananthmsn34 🏅 Dr. Alessandra Boletta (@Boletta_Lab) and Dr. Albert Ong Winners of the Lillian Jean Kaplan International Prize

@torra_roser @SanRaffaeleMI Thank you!🙂

🥳congratulations to #alessandraboletta @SanRaffaeleMI and #albertong @Ong_Lab for winning the prestigious Lillian Jean Kaplan international prize for their contributions to #adpkd 👏🏻👏🏻👏🏻👏🏻👏🏻👏🏻🏆🏆

Congratulations! Looking forward to starting this exciting project with you.

No. 3, Intraflagellar Transport 140 "Monoallelic IFT140 pathogenic variants are an important cause of an autosomal dominant polycystic kidney-spectrum phenotype" @Ong_Lab @johnasayer authors.elsevier.com/c/1eDNsgeW~j5D… alphafold.ebi.ac.uk/entry/Q96RY7

As a community we are devastated by the loss of our dear friend, phenomenal colleague & inspirational leader, Donal O’Donoghue. With Donal’s family’s support we have opened an online memorial page with @RCPLondon so we may all share memories & photos. everloved.com/life-of/donal-…

Excited to announced a 4 year fully funded #PhDposition at my lab to study the intriguing RNA binding proteins of kidney and vascular disease. Deadline 25th of Jan! @FindAPhD @ShefUni_IICD @sheffielduni Check it out here: findaphd.com/phds/project/a…