Shetty Lab

RNA India Meeting 2026 (RIM2026) will be held at IISc, Bangalore, from April 27-29, 2026. We are super excited to reveal the fantastic line-up of speakers. Registration deadline: March 31. Waiver request deadline-March 25. Look forward to welcoming the participants in Bangalore!

The RNA community is gathering — 13th RNA India Meeting 2026 is here! 📍Venue: IISc Bangalore 🎤Submit your abstract soon for a chance to give a short talk! ⏰ Registration closes on March 31st— don't wait! 🔗 rim2026.com #RIM2026 #RNAIndia #RNAResearch #IISc

A major work from our lab is out in Science! @ScienceMag, another key step towards a true demonstration of RNA self-replication. science.org/doi/10.1126/sc… (1/6)

@India_Alliance is looking for a Early Career Fellowship — Basic. 🗓️Deadline: 16 March 2026 Qualification: Entered the final year of PhD or with a maximum of 4 years (*note the exception for Round‑1) of post-PhD research experience at the time of submission of the full application. More details 👇 indiabioscience.org/orgs/the-wellc…

Signaling to make human ribosomes: Connections between the cytoplasm and the nucleolus dlvr.it/TQpQfm

Tata Memorial Hospital @TataMemorial has been serving the nation since 1941, with @ACTREC_TMC added in Navi Mumbai in 2002. We grew from two institutes till 2013 to nine today (and two more upcoming). Our growth accelerated since 2014. Here is the story behind it.

Mizuho Postdoctoral Fellowship at @CRI_ACTREC @ACTREC_TMC My lab will be hosting a postdoc in the following research area! Interested PhD students please apply through the following link: actrec.gov.in/jobs @biopatrika @VoicesofIndAcad

Our lab is inviting applications for the Mizuho Postdoctoral Fellowship 🔬 Focus: Tumor microenvironment in lung & Pancreatic cancers @CRI_ACTREC, Navi Mumbai. Email: sarandkar@actrec.gov.in #PostdoctoralFellow #TumorMicroenvironment #CancerResearch @biopatrika

CRI is pleased to welcome our Cutting Edge Guest speaker for Jan 2026 - Dr. Nitin Mohan from @IITKanpur who will talk about microtubules shape lysosomal signalling. Let's delve deep into organellar biology!! Looking forward to it! @biopatrika @ACTREC_TMC

📢#PublicationAlert 📄 "Altering rRNA 2'O-methylation pattern during neuronal differentiation is regulated by FMRP" In a recent article in 'RNA Biology', we describe a previously unrecognised role for Fragile X Messenger Ribonucleoprotein (FMRP). 🧬 We show that #FMRP regulates 2'O-methylation of ribosomal RNA during neuronal differentiation. By uncovering this new nuclear function in shaping rRNA methylation, we link #ribosome biogenesis to the molecular mechanisms underlying Fragile X Syndrome and related disorders. 🧠 This work, carried out in collaboration with @DBT_inStem, broadens our understanding of ribosome heterogeneity and its role in #brain development. Importantly, it also provides a framework and resource to further explore how RNA modifications influence neuronal identity and function, paving the way to study their role in #dementia and other neurodegenerative conditions. 🔗Read the full story here: tandfonline.com/doi/10.1080/15… @tandfonline @DPalakodeti @RaviMLab @kris_sg

ICAM1 mRNA entraps ILF2/ILF3 to inhibit transcription of EIF4E and global protein synthesis dlvr.it/TQWbTR

Do not miss the TNQ lecture featuring Dr. Bonnie Bassler this year! Register soon :) you are in for a treat! 😍

Online Now: The ribosome synchronizes folding and assembly to promote oligomeric protein biogenesis dlvr.it/TQRVSv

ICMR – Call for Proposals 2026 ICMR invites Investigator-Initiated Research Proposals under ICMR SMALL Extramural Grants (ANVESHAN) (< INR 2 Cr) to support innovative health research aligned with national priorities. Last Date: Mar 16, 2026; 5pm

This work is a reminder that: 👇 The genetic code is not a rigid, universal lookup table. RNA decoding depends on context, molecular structure, and cellular machinery we still only partly understand. Predicting translation from sequence alone remains an open challenge, even decades after sequencing genomes. This is clearly reflected in results from @slavovLab reporting how deviations from the standard genetic code can result in stable and abundant proteins: biorxiv.org/content/10.110… As we push toward deeper mechanistic understanding, this study highlights how much biology still lies beyond the sequence and the simple decoding rules. 2/3

Mechanical forces regulate the composition and fate of stalled nascent chains dlvr.it/TQHL5L

Hypoxia-induced ribosomal RNA modifications in the peptidyl-transferase center contribute to anaerobic growth of bacteria dlvr.it/TQFc7k

@bharatbhatt91 @grewalsh Congratulations Bharat

Silent mode ON 🔕 Cells don’t just inherit chromatin -they update it. Excited to share our lab’s new study, offering a new lens on epigenetic inheritance. Many thanks to Shiv @grewalsh and all the coauthors -couldn’t have done this without you! 🥂 Check it out 👇

Check out our latest work on how collided ribosomes activate the MAP3K ZAK! 💫 nature.com/articles/s4158… A fun collaboration with @BeckmannLab

HYPK promotes N-terminal protein acetylation through rapid ribosome exchange of NatA dlvr.it/TPwM4W