Anu R I
1.1K posts

Anu R I
@anu_iris
Clinician Scientist. AI & Multi-omics. Biochemistry. Cancer Biology & Therapeutics @Harvard #PrecisionOncology #SpaceBiology @University_of_Malta
India, Malta, Belgium انضم Aralık 2018
529 يتبع479 المتابعون
تغريدة مثبتة

Hallmarks of cancer-Then and now, and beyond (2026)
➡️Culminating with #multiomics and #cotargeting
cell.com/cell/fulltext/…
It was an honour to discuss extent of #hallmarks with Prof Hanahan few days ago!
@CellPressNews


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@JayantYGadrey6 @harvardmed @DanaFarber Indeed. Methods of critical thinking, problem solving, future of precision oncology, developing hypotheses were some of the areas discussed. Above all, he was exceptionally kind.
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@anu_iris @harvardmed @DanaFarber Must’ve been an inspiring chat and an incredible opportunity to get pearls of wisdom directly from him!
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2019: At Harvard, was thrilled to listen to Prof William G. Kaelin when he was awarded the Nobel Prize in Medicine
2026: I get the opportunity to discuss my work and receive guidance
Grateful to be conceptually imprinted like so!
@harvardmed @DanaFarber

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Anu R I أُعيد تغريده

Interpreting the results of noninferiority trials—a review
British Journal of Cancer
doi.org/10.1038/s41416…
👏great review
👉option of define advantage beyond efficacy
👉Key is to define clinical noninferiority margin
👉determining its efficacy versus no treatment can be a challenge
@myESMO @ASCO

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Anu R I أُعيد تغريده

Kaushal et al. share EIOC guidelines on liquid biopsy and targeted therapy for early-stage & locally advanced NSCLC in the Middle East and the Indian subcontinent, emphasizing combined liquid+tissue testing for actionable mutations. Read more: bit.ly/3KvGw6S #MedTwitter




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Rewriting epigenetic memory in mouse sperm— allowing erasal of DNA methylation at H19🧬
The result: Offspring with Silver-Russell-like traits
》》》Intergenerational epigenetic inheritance
#Epigenetics #Genetics #Inheritance #Science
nature.com/articles/s4146…

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Some space science art. Crater in Quebec seen from @esa satellite to microscopy of rodent kidney glomerulus, from @KeithSiew et al 2024 PMID: 38862484 @NatureComms exposed to simulated Galactic Cosmic Rays at @NASA Space Radiation Laboratory @BrookhavenLab @mason_lab @AfshinBeheshti @NASAGeneLab @NASAScience_ @ASGSRSpace

Chris Hadfield@Cmdr_Hadfield
This round, delicate Christmas ornament is actually a 214 million-year-old scar in the bedrock of Quebec, from when a 5 km-wide rock smashed into Earth. It hit us in the time of early dinosaurs. The crater is 72 km across, now filled with water for hydroelectric power. Little-known fact: when I was an F-18 pilot, we flew around it at 420 kts, 200 feet above the ice - a unique way to experience the ancient crater. Cool to see from space, too. False-colour image by @esa satellites. Details: esa.int/ESA_Multimedia…
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Glad to be interviewed by @LisaSpiteri13 🙏
#NETondemand #Malta #LiveTelevision🔥
Speaking to tge public on our most recent #cancerresearch project🎗
Link: netondemand.mt/play/35155
Timestamp: 1:02:00 onwards
#precisiononcology #treatmentresistance #oncology


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Happy to be a part of Excellence in oncology care (EIOC) consensus guidelines on #liquidbiopsy and #targetedtherapy in early-stage and locally advanced non-small cell #lungcancer (#NSCLC) for #MiddleEast & #India
@CRSTonline @VanitaNoronha @kumarprabhash


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🗣Honoured to speak at SYNAPSE25: #AI & #MolecularOncology
Organized by Indian Society for Medical and Pediatric Oncology and @IITGuwahati #India
📢FOCUS>>Therapeutic resistance>>Multiomics
#cancerresearch #UNet #LLM #bioinformatics #pathology #multiomics




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TRENDS: From #ASCO to #ESMO 2025: major shifts in cancer trials.
The future of #oncology is Precision>>Earlier>>Smarter.
#CancerResearch #ClinicalTrials #LiquidBiopsy #Immunotherapy #ADC #PrecisionOncology #AIinHealthcare

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@Amolpatel_dr @SidYadavMD @dr_rajapramanik @hoperugo Having said that, there is no concept of mutual exclusivity in biology. Its merely a probability score. Choice of TT would depend on the tumor profile in its entirety>>> personalized in every sense.
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@anu_iris @SidYadavMD @dr_rajapramanik @hoperugo That sounds pretty cool…
You nailed it, the real question in my mind how such observations can be explored for therapeutic arena? I am sure @anu_iris you will have some hypothesis.
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Why Her2neu positive subtype is not known in BRCA positive breast cancers ?
@SidYadavMD @dr_rajapramanik @hoperugo
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🌍 New @NatureMedicine review
WHO’s global analysis of 89,000+ #cancertrials reveals deep inequities!
70% in HICs & <7% in Africa/Asia.
Deadliest cancers (liver, stomach, pancreas, cervix) under-studied.
#CancerResearch #WHO #ESMO #ASCO


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Our new review article in @NatureRevCancer discussing targeting metabolic cell death (#ferroptosis, #cuproptosis and #disulfidptosis) in cancer nature.com/articles/s4156…; rdcu.be/eK7vV
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