Lei Wang

New online! Understanding the therapeutic toolkit for inflammatory bowel disease bit.ly/3Cw8zyS

Big news: Rare back-to-back studies @Nature provide evidence a bile acid called LCA mediates the health & age slowing benefits of low-calorie diets, and may be the elusive endogenous SIRT1 activator that resveratrol mimics. Details below 🧵 tinyurl.com/55dxb859

The human proteomic revolution proceeds with high-throughput assessment, AI analytics, correlation with health and disease, drug interactions, biomarkers cell.com/cell/fulltext/…

@davidjayfrancis This is insane!

Apparently a Bay Area family hired a nanny off the recommendation of her daughter (who allegedly pretended to be a previous client). Nanny goes on to beat the baby all night, caught on camera, then flees back to China. Hard to watch, as a father, this is the kind of thing I'd bring back the death penalty for. @DionLimTV

The prominent role of the gut microbiome in modulating response to stress and circadian rhythm cell.com/cell-metabolis… @Cell_Metabolism open-access, by @jfcryan @gabriel_tofani @UCC and colleagues

Recruitment of Myeloid Derived Suppressor Cells #MDSCs to the neonatal intestine may help ameliorate #NecrotizingEnterocolitis mucosalimmunology.org/article/S1933-…

@themichaelhe @LeukemiaJnl Congratulations, Michael！Its a great job！

Targeting epigenetic disruptions in cancer holds promise. Our latest paper in @LeukemiaJnl reveals a novel viral mimicry-interferon mechanism enhancing HDAC3 inhibition in GNAS knockout lymphoma. Proud to lead this challenging project with an amazing team! nature.com/articles/s4137…

Interested in therapeutic strategies for autoimmune diseases? This Review in the July issue proposes a three-step strategy towards achieving long-term remissions, and discusses approved and investigational therapies for each step bit.ly/3VuIAhO rdcu.be/dNsAE

Medicine-in-the-loop: Thrilled to share our new study starting with a #neoadjuvant #PARPi trial and ending with a next-gen #aCCR8 #Nira combo for #HGSOC! Amazing collaboration between groups of Dr. Qinglei Gao at Tongji Hospital and @lianghantom @MDAndersonNews @bcmhouston 1/14

@theHumanBorch @wusm_pathology Congrats Professor and Happy Father's day！

@HBlackwell17 I believe you will feel better soon. Hugs

This week has been bad. 1. A #AYAsm #leukemia besties passed away. Not all of us get successfully treatments. #AMLsm #BMTsm 2. Having #GVHD sucks 3. Getting a PhD is hard 4. Do I even belong to #celltherapy or #bioengineering 5. Yay, science #keepmovingforward #IntotheNextEra

Thanks @NIH @UFHealthCancer! This is a big effort with two co-PIs Dr Zheng, Guangrong @UFHealthCancer and Dr. Smalley @MoffittNews @LabSmalley to develop next generation PROTACs targeting NR4A1 for potential translation in treating melanoma or other cancer patients.

@Yuewan_Luo @Zhang_Lab_UFL Thanks！

@Zhang_Lab_UFL Congratulations Lei🎉🎉🎉

Please join me to congratulate Dr. Wang!

Sharing a momentous occasion with my dearest mentor @Zhang_Lab_UFL

Please follow this past event and hopefully we can do more in the future to promote accessibility for education, diagnosis, and care for breast cancer patients. Breast Cancer Working Group gathers for networking event » UF Health Cancer Center cancer.ufl.edu/2024/04/25/bre…

Please check out our collaborative work related to children Sjögren’s syndrome. The first single cell transcriptomics of patients blood versus aged matched control or other related symptoms. Dr. Kim,Myung-Chul was a postdoc in my lab, now assistant prof! nature.com/articles/s4200…

NEW content online! Hallmarks of sex bias in immuno-oncology: mechanisms and therapeutic implications dlvr.it/T5Fz27

The Zhang Lab at AACR 2024. Great science and great ceremony.

UF Health Cancer Center researchers have developed a first-of-its-kind compound that could open a new avenue for using immunotherapy to treat various types of #cancer. The findings were published in @JExpMed. Read more: go.ufl.edu/8dtxp9h