AbbyLabby

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AbbyLabby

AbbyLabby

@AbbyLabby_

Therapeutic Editing @ Lilly. Former postdoc @ Doudna Lab & trained @ Pitt #bioE #regenmed #immuno. Science nerd, podcasts, music &🐱Tweets are personal views

Boston, MA Beigetreten Nisan 2019
430 Folgt463 Follower
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Joseph Allen
Joseph Allen@j_g_allen·
Know any kids in your life who want to be a doctor or scientist, with ambitions to cure cancer or find a cure for Alzheimer's that's afflicting a loved grandparent? No exaggeration, what's happening right now means that many, many, many fewer of them will have an opportunity for a summer internship at a hospital or university, be able to do research as a college student, get accepted into a masters program or PhD program. Pitt made the news, but this is already happening everywhere, and it's not just PhD students. Bright, young researchers being laid off, or having job or internship offers rescinded, job postings being pulled... There's a reason this country has been in the lead for so long in biomedical sciences - we train our best and brightest who then go on to do what they dreamed of - finding cures, developing new medicines, inventing new technology to make lives better - all the while boosting the local and national economy. The gutting of NIH will impact everyone in this country, at all income levels, in red/blue states, in all types of jobs - scientists and janitors, food prep workers and lab techs, bus drivers and high school interns.
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Jennifer R Hamilton
Jennifer R Hamilton@JRo_Hamilton·
From exploring bio-entrepreneurship to securing $1 million in non-dilutive funding, the HS Chau WIES award transformed my career. This program empowers women interested in enterprising science; if that's you, apply now! Applications for the next cohort are due April 12 👩‍🔬
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Kai Chen
Kai Chen@kaichen_1990·
My second project @doudna_lab also has a topic on RNP delivery for genome editing in vivo. Different from using LNPs to package and transport gene editors, we engineered self-deliverable Cas9 RNPs through fusion to cell-penetrating peptides (CPPs). biorxiv.org/content/10.110…
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AbbyLabby
AbbyLabby@AbbyLabby_·
Display at Christmas 🎄 or all year? 😄
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AbbyLabby@AbbyLabby_·
4.5 years apart, and just like that postdoc is coming to an end! 🥲 The good news is that no, I’m not done CRISPRing! I’ll keep working on therapeutic apps of gene editing @EliLillyandCo. So grateful for my time in @doudna_lab at @igisci, could not ask for a better place to train
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AbbyLabby
AbbyLabby@AbbyLabby_·
Also I loved seeing the back-to-back articles with some amazing work from UPenn further demonstrating the high efficiency of the peptide-mediated Cas9 delivery approach! nature.com/articles/s4158…
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AbbyLabby
AbbyLabby@AbbyLabby_·
Exciting week for #CRISPR RNP delivery! The addition of cell penetrating peptides in trans enables Cas9 entry and editing of T-cells 😯🤩 Super work @RossWilsonLab
Ross Wilson@RossWilsonLab

I’m excited to share our report - out now in @natBME - of a new approach to CRISPR delivery that is poised to transform the way engineered T cell therapies are manufactured. Visit tinyurl.com/CRISPR-PERC for “how to” details. It’s threadin’ time! (1/11) nature.com/articles/s4155…

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AbbyLabby
AbbyLabby@AbbyLabby_·
Excited to share this pre-print on recent developments in non-viral delivery of CRISPR-Cas9 to the mouse brain, following up on work from the @doudna_lab published in 2017 biorxiv.org/content/10.110…
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AbbyLabby
AbbyLabby@AbbyLabby_·
Thanks to my co-authors and collaborators! Looking forward to applying this delivery strategy to therapeutically relevant loci in the near future!
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AbbyLabby@AbbyLabby_·
The RNP did initially trigger a microglia response that could be mitigated by further reducing endotoxin during recombinant protein production scale up with partners @aldevron
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Dr. Liana Lareau
Dr. Liana Lareau@lianafaye·
For the past year I've had the amazing luxury of weekly covid tests on campus. It was so valuable to track the local asymptomatic positive rate. Last week was the all-time high: 4% of people without symptoms or exposure tested positive. They shut down the testing program Friday.
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