Jennifer R Hamilton

I’m excited to share our work developing an antibody-directed strategy for delivering genome engineering tools to specific cell types, both outside and inside the body 🎯

I am so excited to share our new paper in @Nature: the first programmable, site-specific integration of a large DNA payload into T cells in vivo. A single IV injection results in therapeutic levels of TRAC-targeted CAR T cells in multiple models. #Ack1" target="_blank" rel="nofollow noopener">nature.com/articles/s4158… a 🧵

Hello! Anyone on here a member of ASH? I’m looking for someone who could sponsor a late-breaking abstract. If you can help or make an intro, please DM me. Thanks! 🙏

How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/…

From exploring bio-entrepreneurship to securing $1 million in non-dilutive funding, the HS Chau WIES award transformed my career. This program empowers women interested in enterprising science; if that's you, apply now! Applications for the next cohort are due April 12 👩‍🔬

The future of genome editing is in vivo! Check out our latest @PNASNews perspective from @doudna_lab. Had a lot of fun discussions with @kevin_wasko and @JRo_Hamilton about the past, present, and future of in vivo delivery. pnas.org/doi/10.1073/pn…

#CRISPR gene therapy could be less painful and less costly with in vivo delivery of gene editing tools. A new delivery method could achieve cell-specific DNA editing in the body. @UCBerkeley @igisci buff.ly/3SHY9Av

Enveloped Delivery Vehicles Enable Targeted Genome Engineering of Human Cells Scientists created enveloped delivery vehicles that can carry Cas9 and gRNA proteins for precise genome editing in living organisms. Learn more: ow.ly/HXIq50QwMjt

Making CAR T cells in vivo (& with a TRAC knockout) using a new cell type-specific delivery vehicle! Cool study from @doudna_lab in @NatureBiotech

Packaging and delivery of genome-editing tools go.nature.com/49g3qWk #ResearchHighlight by @LinkoNRG

@doudna_lab @berkeleyMCB @igisci @QB3 @UCB_Chemistry @GladstoneInst @HHMINEWS @LBNLBioSci @JRo_Hamilton Research Highlight: Packaging and delivery of genome-editing tools - @LinkoNRG @NatureRevGenet nature.com/articles/s4157…

My emotional COI here is taller than the Burj Khalifa. With that disclosure: nature.com/articles/s4158… behold beautiful work by the brilliant @JRo_Hamilton @doudna_lab @igisci on what I personally think will be THE paradigm for immune system genome editing for both oncology and other disease indications.

This research was a true team effort! It was such a privilege to work on this project in the @doudna_lab with @evelyn_chen11, @b_s_perez, @CindySE27, Min Hyung Kang, Marena Trinidad, and @WayneNgo1. And a big thank you to @igisci for championing this work!

We are excited about this approach’s potential to leverage programmable targeting molecules for delivering genome editors (or other cargo!) to specific, therapeutically relevant cell types inside the body. We are grateful to our collaborators & funders for enabling this project🙏

I’m excited to share our work developing an antibody-directed strategy for delivering genome engineering tools to specific cell types, both outside and inside the body 🎯

Exciting news – our paper is out! 🎉 Teaming up with @JRo_Hamilton and @evelyn_chen11 was incredible – they’re rockstar scientists! Major shoutout to all involved in this journey 🌟 The @doudna_lab’s vibrant energy certainly amped my enthusiasm for gene and cell therapies! 🧬👩🏽‍🔬