NG20194

@abledoc @__ice9 @farid__jalali Severe COVID-19: Immune system derails Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction. sciencedaily.com/releases/2020/…

@Yoda4ever Babies and their animal friends are simply amazing to watch

Baby's happiness seeing her pony friends..🐴👧 📹teddytheshetIand

@deepduttaendo Sir any generic GLP-1 agonist drug available in India for patients with nausea/delayed gastric motility issues?

Orforglipron has one of the best weight loss data among all the oral GLP1 receptor agonism based medicines It can cause on an average 9% weight loss from baseline 24-36mg/d daily oral dose is best suited dose range for use A big thanks to all the authors & Wiley for recognising our work, one of the first meta-analysis ever published on the clinical efficacy & safety of orforglipron use Full text at: onlinelibrary.wiley.com/doi/10.1002/os… @abm_kamrul @IndiaESI @Rssdi_official @WileyLifeSci @ObesitySociety @WorldObesity @ChildObesity_jn @RCSI_Obesity @CD8ProbSolvers7 @OHA_updates @UK_ASO @ObesityAction @ObesityCan

@Iynjurldient Thanks, James. Much appreciated.

@NG20194 Please keep me informed of what you find, if you are comfortable with that. I am eager to know what you discover and if I can help.

Most Vaccine Injured people have Ehlers Danlos Syndrome in my opinion based on my observations of other patients. They presented as healthy until the vaccine turned those genes “on.” Vaccines can be a “trigger” for chronic disease primarily Autonomic Nervous System Dysfunction.

@Iynjurldient Other LLMs diagnose as CFS and Fibromyalgia, hypertension, mast cell activation syndrome, possibly SFN with overactive sympathetic nervous system

@Iynjurldient It says "You are presenting with multiple neurological and systemic symptoms that may be interconnected. A professional review is necessary to distinguish between possible neurological conditions and manage overlapping symptoms effectively."

@Iynjurldient Schedule an Appointment with the Neurologist

@NG20194 what did it say?

@Iynjurldient I have updated the details in the Advocate AI app.

@Iynjurldient @AutonomicBrad I understand that. Definitely, it's not a medical advice but trying to help connect the dots to get some relief from this horrific condition.

@Iynjurldient @AutonomicBrad James you have done a great research work. Looks like a straight from a Sci-Fi movie. Wish I could share my symptoms with you and you could help me understand what can help me.

@NG20194 @AutonomicBrad x.com/Iynjurldient/s…

@Iynjurldient @AutonomicBrad What's the cure?

@AutonomicBrad good thing there's a cure for that.

@agingdoc1 Excess of anything is dangerous.

Vitamin B3 derivatives support pancreatic cancer cell survival and chemotherapy resistance sciencedirect.com/science/articl…

@BrandonLuuMD Creatine is good for cognitive health but it causes digestive issues. Maybe need to correct what is really broken in the gut.

In patients with depression already on antidepressants, adding creatine + Bifidobacterium increased plasma creatine and reduced depression scores. Mouse data suggest a possible reason: restored intestinal creatine transport.

@mecfsskeptic @JanetDafoe @DafoeWhitney @CatchTheBaby We need to consider high dose IVIG (as shown in the recent Lancet case study) and steroids as shown by @BrainInflCollab case study in a subset of ME/CFS patients.

1) 🇦🇹 A Post-COVID Rehabilitation clinic in Vienna found that 15 out of 216 (7%) Long Covid patients met the Canadian criteria for ME/CFS. ME/CFS patients were younger, more often female, more fatigued and had a worse trajectory than those without ME/CFS.

@im_vakil Superb at such a young age. I'm damn sure she would be in Indian Women's Cricket Team.

Look her finger 🤞🔥

@Astrotherapist1 Ma'am are we seeing massive unemployment and job losses in near future like post 2027? War has already impacted the global economy.

Just today i wrote this prediction and we can start seeing the impact.

@jadethebpdcoach How much does it cost to get treated at Mayo Clinic?

It is confirmed, along with a BPD diagnosis now in remission, I have epilepsy originating in the left temporal lobe. I have been to dozens of doctors, psychiatrists, and therapists since I was a teenager. People with excellent credentials, years of experience. None come close to the level of care I’ve received here on my first day at the #mayoclinic Thank God for this place. I hope if you have a complicated medical history, you get the chance to come here. You will not regret it.

@LexTemperatus @anishmoonka Can the gut microbiome changes trigger sympathetic overactivity, dysregulate nervous system or worsen the stress response?

@anishmoonka Improving diet and gut health helps, but if your nervous system stays dysregulated, the effect won’t stick.

Your gut makes 95% of your body's serotonin, the same chemical that antidepressants are designed to increase. Your brain makes the other 5%. This 2016 study took stool samples from 34 people with major depression, wiped the gut bacteria out of a group of rats with antibiotics, and transplanted the depressed patients' bacteria into them. The rats stopped chasing rewards they had once enjoyed. They got more anxious. The chemical levels in their blood shifted to look like the depressed patients'. These rats weren't drugged or put under stress. They just received bacteria from depressed people, and their behavior changed on its own. Your gut wall is lined with about 500 million nerve cells, more than your spinal cord. This network operates so independently that it can process what's happening in your digestive tract and respond to it without ever checking in with your brain. Scientists call it the "second brain." The main wire connecting the two is the vagus nerve, and roughly 80% of the signals traveling on it run upward, from the gut to the brain. Your gut has more to say to your head than your head has to say to your gut. The serotonin part comes down to food. You eat turkey, eggs, or cheese, and your body releases a nutrient called tryptophan. Normally, that gets converted into serotonin. But certain gut bacteria grab that tryptophan first and burn through it before your body can use it to make serotonin. Less raw material for serotonin means less serotonin gets built. When researchers moved depressed patients' bacteria into rats, the same thing happened. This wasn't a one-off. A separate team published the same result in Molecular Psychiatry that year using mice born and raised in sterile labs with zero bacteria. Those mice have 2.8x less serotonin than normal mice. A 2011 Karolinska Institute study found that if you wait too long to introduce bacteria into these sterile mice, some of the brain changes can become permanently locked in. There's a window during which gut microbes help wire the developing brain, and once it closes, the wiring holds. The obvious next step is to test the reverse: pushing healthy bacteria into sick people. A 2025 review in Nutrients examined 19 clinical trials testing probiotics (specific bacterial strains taken as supplements) on people diagnosed with depression. All 19 showed reduced symptoms. The field now calls these mood-targeting bacteria "psychobiotics," a term coined in 2013 by researchers at this same University College Cork lab. The trillion bacteria in your gut do more than digest food. They manufacture brain chemicals and fire signals up a nerve highway to your skull every second you're alive. This study showed that you can transplant depression between species by moving bacteria. 19 out of 19 clinical trials say the reverse works too.

@LauraDelano Thanks, Laura. It's a massive struggle to come off an anti-depressant.

New! Online now: The gut microbiota alleviates depression by remodeling gut-brain energy metabolism dlvr.it/TRp62v