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Very happy to share our latest preprint, where we address the relationship between systemic and gut IgA. See link below and details in 🧵. Huge thanks to everyone involved!
biorxiv.org/content/10.110…
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Rasmus Iversen
136 posts
Rasmus Iversen
@RasmusIv
Immunologist and B-cell enthusiast at Oslo University Hospital.
Oslo, Norway Beigetreten Ağustos 2018
281 Folgt354 Follower
Rasmus Iversen retweetet
My lab is looking for an antibody engineer-protein biochemist to study ~500 patient derived monoclonal antibodies. Towards novel insights into autoAb-mediated neurological diseases #encephalitis #nmo #protein #antibody
Come n work at wonderful @MayoClinic Florida🏖️
Pls email me
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Collectively, our results suggest that systemic and gut IgA responses against bacteria originate from discrete anatomical sites with inductive sites in the upper aerodigestive tract likely playing a prominent role in generation of systemic IgA.
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Notably, while IgA plasma cells in the bone marrow were almost exclusively of the IgA1 subclass, gut plasma cells showed an equal distribution between IgA1 and IgA2.
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Very happy to share our latest preprint, where we address the relationship between systemic and gut IgA. See link below and details in 🧵. Huge thanks to everyone involved!
biorxiv.org/content/10.110…
English
I am looking for a PhD candidate to join my lab in Oslo! We are trying to understand the role of antigen-specific B cells in autoimmunity. See details and apply here 👇
2411.webcruiter.no/Main2/Recruit/…
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Very excited to share our paper on enzyme-activating BCRs and their role in gluten-sensitive autoimmunity!
rdcu.be/ecXfG
bsky.app/profile/rasmus…
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Rasmus Iversen retweetet
We have an open 2-year postdoc position focusing on computational approaches to identify antigen-specific immune receptors from adaptive immune repertoire data. Application deadline: Nov 6. jobbnorge.no/en/available-j…
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Rasmus Iversen retweetet
So excited! Hot off the press in @Nature
We present a human autoimmune organoid model capable of mimicking celiac disease. | driven by Antonio Santos! | Calvin Kuo Lab @StanfordMed
nature.com/articles/s4158…
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Rasmus Iversen retweetet
Our paper on the linguistics-based formalization of antibody language is out in @NatComputSci. Work led by @MaiSpaceHa Rahmad Akbar and @PRobertImmodels . Summary thread: x.com/PRobertImmodel….
Nature Computational Science@NatComputSci
📢 @maispaceha, @PRobertImmodels, @BartlomiejSwia4, @SandveGeir, @victorgreiff et al. explore the potential of linguistic formalization of antibody language to improve rule mining in deep LMs for antibody sequence analysis. nature.com/articles/s4358… ➡️rdcu.be/dKOdq
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Happy to share this story on autoreactive naive B cells of relevance to celiac disease. Out now in the Journal of Autoimmunity. More details in 🧵 sciencedirect.com/science/articl…
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Collectively, our study highlights the role of efficient T cell-B cell collaboration in development of celiac disease and production of disease-specific autoantibodies.
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The selected B cells are the ones that can interact productively with gluten-specific T cells. This requires that the B cells bind active TG2, which can form complexes with gluten. Hence, only some epitopes are permissive, and these end up dominating the autoantibody response.
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Our paper on circulating autoreactive B cells in celiac disease is now out in @CellReports 🎉. Big thanks to everyone involved!
#secsectitle0260" target="_blank" rel="nofollow noopener">cell.com/cell-reports/f…
Rasmus Iversen@RasmusIv
Very happy to share this story on autoreactive B cells in celiac disease together with @IdaLindeman @LeneHoydahl @ChristophAsb @LouiseFRisnes @JCoDiRC. Here, we identify a population of circulating IgA-switched B cells specific to the self-antigen transglutaminase 2 (TG2).
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Rasmus Iversen retweetet
I am so happy to share that our study has been published today in @Nature ! 🎉This has been an absolutely fantastic teamwork between @emilyethornton, @haemyisu @powrie_lab and @teichlab [Link: rdcu.be/dDzwx]
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Rasmus Iversen retweetet
New opening for a PhD student in my lab, co-supervised with @F_Lund_Johansen . This position is ERC-funded and focuses on novel experimental technologies for antibody-antigen binding screening 📷 jobbnorge.no/en/available-j…
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